Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735619 . C A CCDS2362.1:NM_005214.4:c.420taC>taA_NP_005205.2:p.140Y>* Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 TYR A:105 A:105 110.0 0.478 E -131.1 138.4 110.0 0.478 0.0 GOL
HOH
 3.118
3.108
 CD1
OH
 O1
O
TYR B:105 B:105 75.0 0.326 E -123.5 145.3 75.0 0.326 0.0 HOH
 3.139
 CA
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 TYR C:106 C:140 57.0 0.248 E -126.0 142.4 NA NA NA
TYR F:106 F:140 57.0 0.248 E -125.6 140.9 NA NA NA
TYR I:106 I:140 59.0 0.257 E -127.4 140.5 NA NA NA
TYR L:106 L:140 60.0 0.261 E -132.3 140.2 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 TYR C:105 C:105 125.0 0.543 171.3 105.7 125.0 0.543 0.0
TYR D:105 D:105 126.0 0.548 177.7 123.5 78.0 0.339 0.209 B:P42081:0.209
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 TYR C:105 Y:105 99.0 0.43 E -130.1 140.1 44.0 0.191 0.239 A:None:0.239
 HOH
 2.782
 OH
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 TYR E:105 c:105 75.0 0.326 E -130.3 140.2 NA NA NA
TYR F:105 C:105 65.0 0.283 E -128.6 139.2 41.0 0.178 0.105 B:None:0.104
 HOH
 3.712
 CD1
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 TYR C:105 C:105 92.0 0.4 E -126.8 140.5 48.0 0.209 0.191 A:P33681:0.191
TYR D:105 D:105 85.0 0.37 E -132.1 132.9 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 TYR A:106 D:105 208.0 0.904 -117.0 131.5 41.0 0.178 0.726 A:P16410:0.726
 HOH
 2.909
 OH
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 TYR A:104 A:105 200.0 0.87 -160.6 108.0 200.0 0.87 0.0 FUL
 7.281
 OH
 H61
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 TYR B:104 A:105 65.0 0.283 E -121.3 137.8 41.0 0.178 0.105 A:None:0.104
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 TYR A:103 C:105 117.0 0.509 E -156.7 164.7 9.0 0.039 0.47 B:None:0.47
 HOH
 2.899
 OH
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 TYR A:103 A:105 97.0 0.422 E -126.7 158.3 2.0 0.009 0.413 B:None:0.209
C:None:0.274
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 TYR A:104 A:105 78.0 0.339 E -123.8 135.1 NA NA NA
TYR C:104 C:105 77.0 0.335 E -124.1 136.8 NA NA NA
TYR E:104 E:105 79.0 0.343 E -122.2 136.1 NA NA NA
TYR G:104 G:105 82.0 0.357 E -124.8 135.4 82.0 0.357 0.0
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 TYR A:105 A:105 67.0 0.291 E -124.0 140.6 67.0 0.291 0.0 HOH
 3.752
 CA
 O
TYR C:105 C:105 77.0 0.335 E -113.7 139.1 NA NA NA
TYR E:105 E:105 102.0 0.443 E -104.5 136.9 NA NA NA
TYR G:105 G:105 100.0 0.435 E -120.6 135.5 100.0 0.435 0.0 HOH
 7.927
 O
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 TYR E:104 c:105 77.0 0.335 E -121.0 136.5 NA NA NA
TYR F:104 C:105 71.0 0.309 E -125.2 143.1 48.0 0.209 0.1 A:None:0.1
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 TYR E:104 C:105 71.0 0.309 E -126.3 138.6 NA NA NA
TYR F:104 c:105 67.0 0.291 E -128.8 137.0 47.0 0.204 0.087 B:None:0.087
 HOH
 7.409
 C
 O
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 TYR A:110 A:138 54.0 0.235 E -127.7 145.7 54.0 0.235 0.0 HOH
 2.919
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 TYR A:140 A:140 33.0 0.143 E -119.6 139.0