Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735635 . G A CCDS2362.1:NM_005214.4:c.436Gga>Aga_NP_005205.2:p.146G>R Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 GLY A:111 A:111 5.0 0.067 91.9 136.2 5.0 0.067 0.0 GOL
HOH
 6.304
2.789
 N
O
 O1
O
GLY B:111 B:111 6.0 0.08 96.4 145.3 6.0 0.08 0.0 HOH
 2.945
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 GLY C:112 C:146 11.0 0.147 121.9 142.5 NA NA NA
GLY F:112 F:146 11.0 0.147 118.2 141.0 NA NA NA
GLY I:112 I:146 10.0 0.133 119.2 145.4 NA NA NA
GLY L:112 L:146 11.0 0.147 128.9 150.3 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 GLY C:111 C:111 13.0 0.173 76.9 133.6 13.0 0.173 0.0
GLY D:111 D:111 13.0 0.173 71.0 141.8 13.0 0.173 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 GLY C:111 Y:111 3.0 0.04 93.4 142.3 3.0 0.04 0.0 HOH
 4.124
 O
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 GLY E:111 c:111 6.0 0.08 100.8 145.7 NA NA NA
GLY F:111 C:111 8.0 0.107 101.7 145.9 8.0 0.107 0.0 HOH
 4.370
 N
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 GLY C:111 C:111 7.0 0.093 83.3 133.4 7.0 0.093 0.0 NAG
 7.298
 N
 O7
GLY D:111 D:111 6.0 0.08 119.0 156.4 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 GLY A:112 D:111 66.0 0.88 110.4 152.6 5.0 0.067 0.813 A:P16410:0.813
 HOH
 2.716
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 GLY A:110 A:112 12.0 0.16 129.6 143.1 12.0 0.16 0.0 NAG
 4.811
 N
 H83
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 GLY B:110 A:111 28.0 0.373 -62.9 156.6 22.0 0.293 0.08 A:None:0.08
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 GLY A:109 C:111 7.0 0.093 91.6 154.6 7.0 0.093 0.0 HOH
 2.768
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 GLY A:109 A:111 5.0 0.067 101.8 144.4 5.0 0.067 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 GLY A:110 A:111 7.0 0.093 114.4 150.3 NA NA NA
GLY C:110 C:111 8.0 0.107 112.4 149.9 NA NA NA
GLY E:110 E:111 8.0 0.107 113.1 150.4 NA NA NA
GLY G:110 G:111 7.0 0.093 113.0 147.5 7.0 0.093 0.0 NAG
 6.983
 N
 C1
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 GLY A:111 A:111 4.0 0.053 97.4 146.8 4.0 0.053 0.0 HOH
 2.897
 O
 O
GLY C:111 C:111 3.0 0.04 93.8 153.1 NA NA NA
GLY E:111 E:111 7.0 0.093 95.2 140.0 NA NA NA
GLY G:111 G:111 7.0 0.093 116.4 127.7 7.0 0.093 0.0
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 GLY E:110 c:111 6.0 0.08 95.4 141.5 NA NA NA
GLY F:110 C:111 11.0 0.147 110.7 150.0 11.0 0.147 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 GLY E:110 C:111 4.0 0.053 98.2 152.4 NA NA NA
GLY F:110 c:111 5.0 0.067 97.7 149.3 5.0 0.067 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 GLY A:116 A:144 4.0 0.053 97.6 140.9 4.0 0.053 0.0 HOH
 2.960
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 GLY A:146 A:146 7.0 0.093 93.1 149.8