Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922271 . G A CCDS33380.1:NM_002181.3:c.461aCc>aTc_NP_002172.2:p.154T>I Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 THR A:139 B:154 2.0 0.014 E -141.6 -179.2 2.0 0.014 0.0 HOH
 6.381
 OG1
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 THR A:139 B:154 2.0 0.014 E -140.8 179.8 2.0 0.014 0.0 HOH
 6.356
 OG1
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 THR A:139 B:154 3.0 0.021 E -141.2 -178.5 3.0 0.021 0.0 SO4
HOH
 3.963
3.435
 CG2
CG2
 O1
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 THR A:139 B:154 2.0 0.014 E -135.5 -179.5 2.0 0.014 0.0 SO4
HOH
 7.859
3.600
 OG1
CG2
 O3
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:130 A:154 3.0 0.021 E -136.4 177.9 1.0 0.007 0.014 D:Q4KMG0:0.014
 HOH
 3.043
 HG21
 O
THR B:130 B:154 3.0 0.021 E -137.3 -179.0 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:130 B:154 2.0 0.014 E -137.2 179.0 1.0 0.007 0.007 B:Q9BWV1:0.007
 HOH
 3.063
 HG21
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:130 A:154 1.0 0.007 E -147.8 -180.0 1.0 0.007 0.0 HOH
 3.386
 CG2
 O
THR B:130 B:154 1.0 0.007 E -149.2 179.3 NA NA NA
THR C:130 C:154 2.0 0.014 E -134.0 179.6 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:130 B:154 0.0 0.0 E -141.9 -172.6 0.0 0.0 0.0
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 THR B:129 B:149 3.0 0.021 E -139.1 -176.9 2.0 0.014 0.007 A:Q13635:0.007
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:126 C:149 3.0 0.021 E -115.5 177.5 0.0 0.0 0.021 A:Q13635:0.021
 CA
 9.883
 CG2
 CA
THR F:126 F:149 3.0 0.021 E -115.5 177.4 0.0 0.0 0.021 D:Q13635:0.021
 CA
 9.883
 CG2
 CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:126 C:149 4.0 0.029 E -115.5 177.4 0.0 0.0 0.029 A:Q13635:0.029
 CA
 9.884
 CG2
 CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:126 C:149 3.0 0.021 E -115.5 177.5 0.0 0.0 0.021 A:Q13635:0.021
 CA
 9.883
 CG2
 CA
THR F:126 F:149 3.0 0.021 E -115.5 177.4 0.0 0.0 0.021 D:Q13635:0.021
 CA
 9.883
 CG2
 CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 THR C:126 C:149 2.0 0.014 E -136.2 -172.2 0.0 0.0 0.014 B:Q13635:0.014
 ZN
 9.996
 N
 ZN
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 THR B:127 C:149 6.0 0.043 E -135.2 176.6 0.0 0.0 0.043 C:Q13635:0.043
 CA
 9.849
 OG1
 CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 THR B:127 C:149 4.0 0.029 E -111.1 175.1 4.0 0.029 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 THR A:127 A:149 1.0 0.007 E -135.5 178.5 1.0 0.007 0.0 SO4
HOH
 7.831
3.678
 OG1
CG2
 O1
O
THR B:127 B:149 2.0 0.014 E -142.6 178.4 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 THR C:121 H:149 2.0 0.014 E -141.9 177.5 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 THR A:121 A:149 1.0 0.007 E -140.0 -179.4 0.0 0.0 0.007 C:None:0.007
 HOH
 3.592
 CG2
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 THR A:121 A:149 2.0 0.014 E -140.8 -179.4 2.0 0.014 0.0 CL
HOH
 7.290
2.829
 OG1
HG21
 CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 THR B:237 B:149 2.0 0.014 E -170.1 179.3 0.0 0.0 0.014 A:Q13635+U6GSR1:0.014
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 THR A:117 A:150 1.0 0.007 E -151.6 178.5 1.0 0.007 0.0 SO4
HOH
 4.143
2.893
 CG2
CG2
 O1
H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 THR A:129 A:150 3.0 0.021 E -135.7 176.3 1.0 0.007 0.014 D:Q4KMG0:0.014
 HOH
 3.897
 CG2
 O
THR B:129 B:150 3.0 0.021 E -136.4 -178.3 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 THR B:125 H:150 2.0 0.014 E -142.5 173.1 2.0 0.014 0.0 SO4
 4.362
 CG2
 O3
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 THR A:113 A:150 3.0 0.021 E -140.2 -177.1 3.0 0.021 0.0 ASG
ACT
HOH
 7.669
4.073
3.695
 OG1
CG2
CG2
 OSB
O
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 THR A:113 A:150 1.0 0.007 E -139.7 -179.1 1.0 0.007 0.0 SGN
IDS
SGN
 8.450
6.060
6.886
 CG2
CG2
OG1
 O4
O2S
O2S
THR B:113 B:150 4.0 0.029 E -138.5 -179.2 4.0 0.029 0.0 SGN
IDS
SGN
IDS
HOH
 7.642
7.158
4.760
9.819
7.284
 OG1
CG2
CG2
CG2
OG1
 O1S
O6A
O4S
C1
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 THR A:115 A:150 1.0 0.007 E -134.6 -176.2 1.0 0.007 0.0 HOH
 3.855
 CG2
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 THR A:111 A:150 2.0 0.014 E -141.8 174.5 0.0 0.0 0.014 B:Q96QV1:0.014
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 THR A:111 A:150 1.0 0.007 E -148.5 179.8 0.0 0.0 0.007 B:Q96QV1:0.007

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 THR A:154 A:154 2.0 0.014 E -138.3 174.0