Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922369 . C A CCDS33380.1:NM_002181.3:c.363caG>caT_NP_002172.2:p.121Q>H Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 GLN A:106 B:121 68.0 0.378 H -67.0 -42.2 68.0 0.378 0.0 HOH
 2.707
 O
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLN A:106 B:121 68.0 0.378 H -67.6 -42.1 68.0 0.378 0.0 HOH
 2.725
 O
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLN A:106 B:121 66.0 0.367 H -65.9 -42.9 66.0 0.367 0.0 HOH
 2.694
 O
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLN A:106 B:121 69.0 0.383 H -55.2 -47.3 69.0 0.383 0.0 HOH
 2.494
 OE1
 O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLN A:97 A:121 79.0 0.439 H -75.1 -43.7 79.0 0.439 0.0 HOH
 2.328
 HE22
 O
GLN B:97 B:121 84.0 0.467 H -73.2 -39.0 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLN A:97 B:121 22.0 0.122 H -75.8 -39.1 22.0 0.122 0.0 HOH
 2.235
 HE22
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLN A:97 A:121 76.0 0.422 H -72.4 -41.7 76.0 0.422 0.0 HOH
 3.321
 OE1
 O
GLN B:97 B:121 76.0 0.422 H -66.4 -50.7 NA NA NA
GLN C:97 C:121 77.0 0.428 H -71.7 -57.8 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLN A:97 B:121 22.0 0.122 H -79.4 -52.2 22.0 0.122 0.0 HOH
 5.531
 O
 O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 GLN B:96 B:116 82.0 0.456 T -103.2 -55.2 82.0 0.456 0.0
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLN C:93 C:116 66.0 0.367 H -71.5 -45.3 36.0 0.2 0.167 B:Q13635:0.167
GLN F:93 F:116 65.0 0.361 H -71.6 -45.2 35.0 0.194 0.167 E:Q13635:0.167
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLN C:93 C:116 67.0 0.372 H -71.5 -45.2 35.0 0.194 0.178 B:Q13635:0.178
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLN C:93 C:116 66.0 0.367 H -71.5 -45.3 36.0 0.2 0.167 B:Q13635:0.167
GLN F:93 F:116 65.0 0.361 H -71.6 -45.2 35.0 0.194 0.167 E:Q13635:0.167
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 GLN C:93 C:116 79.0 0.439 H -81.8 -59.5 22.0 0.122 0.317 A:Q13635:0.317
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 GLN B:94 C:116 80.0 0.444 H -71.7 -49.4 27.0 0.15 0.294 A:Q13635:0.294
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 GLN B:94 C:116 74.0 0.411 H -65.8 -57.6 64.0 0.356 0.055 A:Q13635:0.056
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 GLN A:94 A:116 87.0 0.483 H -71.3 -44.2 87.0 0.483 0.0 HOH
 2.710
 O
 O
GLN B:94 B:116 81.0 0.45 H -71.4 -48.3 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 GLN C:88 H:116 68.0 0.378 H -67.8 -48.1 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 GLN A:88 A:116 77.0 0.428 H -65.4 -48.7 77.0 0.428 0.0 HOH
 2.710
 O
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 GLN A:88 A:116 73.0 0.406 H -70.1 -42.3 73.0 0.406 0.0 GOL
HOH
 1.953
2.481
 HE21
HE22
 O3
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 GLN B:204 B:116 65.0 0.361 S -83.4 139.8 65.0 0.361 0.0
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 GLN A:84 A:117 66.0 0.367 H -72.7 -43.1 66.0 0.367 0.0 HOH
 2.442
 OE1
 H1
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 GLN A:96 A:117 82.0 0.456 H -71.0 -43.0 82.0 0.456 0.0 HOH
 2.444
 O
 O
GLN B:96 B:117 67.0 0.372 H -60.7 -45.5 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 GLN B:92 H:117 86.0 0.478 H -69.1 -44.1 86.0 0.478 0.0
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLN A:80 A:117 88.0 0.489 H -72.6 -43.5 88.0 0.489 0.0 HOH
 2.900
 O
 O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLN A:80 A:117 81.0 0.45 H -71.0 -47.3 81.0 0.45 0.0 HOH
 6.987
 N
 O
GLN B:80 B:117 84.0 0.467 H -70.5 -47.1 84.0 0.467 0.0 HOH
 7.124
 N
 O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 GLN A:82 A:117 77.0 0.428 H -72.3 -42.6 77.0 0.428 0.0 HOH
 3.576
 OE1
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 GLN A:78 A:117 81.0 0.45 H -86.6 -48.8 81.0 0.45 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 GLN A:78 A:117 80.0 0.444 H -73.2 -53.7 80.0 0.444 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 GLN A:121 A:121 72.0 0.4 H -74.4 -36.3