Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922380 . C A CCDS33380.1:NM_002181.3:c.352Gtg>Ttg_NP_002172.2:p.118V>L Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 VAL A:103 B:118 0.0 0.0 H -66.6 -45.0 0.0 0.0 0.0 HOH
 4.168
 CB
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 VAL A:103 B:118 0.0 0.0 H -63.5 -45.1 0.0 0.0 0.0 HOH
 4.243
 CB
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 VAL A:103 B:118 0.0 0.0 H -66.1 -45.1 0.0 0.0 0.0 HOH
 4.237
 CB
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 VAL A:103 B:118 0.0 0.0 H -61.9 -46.0 0.0 0.0 0.0 HOH
 4.410
 CB
 O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:94 A:118 0.0 0.0 H -65.2 -45.2 0.0 0.0 0.0 HOH
 3.313
 HB
 O
VAL B:94 B:118 0.0 0.0 H -64.2 -47.4 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:94 B:118 0.0 0.0 H -64.9 -47.6 0.0 0.0 0.0 HOH
 3.354
 HB
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:94 A:118 0.0 0.0 H -60.0 -45.8 0.0 0.0 0.0 HOH
 4.476
 CB
 O
VAL B:94 B:118 0.0 0.0 H -59.9 -51.2 NA NA NA
VAL C:94 C:118 0.0 0.0 H -62.6 -46.1 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:94 B:118 0.0 0.0 H -73.4 -44.6 0.0 0.0 0.0 HOH
 7.837
 O
 O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 VAL B:93 B:113 0.0 0.0 H -69.7 -41.5 0.0 0.0 0.0
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:90 C:113 0.0 0.0 H -75.2 -41.0 0.0 0.0 0.0
VAL F:90 F:113 0.0 0.0 H -75.2 -41.0 0.0 0.0 0.0
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:90 C:113 0.0 0.0 H -75.2 -41.0 0.0 0.0 0.0
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:90 C:113 0.0 0.0 H -75.2 -41.0 0.0 0.0 0.0
VAL F:90 F:113 0.0 0.0 H -75.2 -41.0 0.0 0.0 0.0
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 VAL C:90 C:113 0.0 0.0 H -75.3 -43.8 0.0 0.0 0.0
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 VAL B:91 C:113 0.0 0.0 H -74.2 -42.7 0.0 0.0 0.0
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 VAL B:91 C:113 3.0 0.019 H -79.4 -31.9 3.0 0.019 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 VAL A:91 A:113 0.0 0.0 H -57.8 -46.9 0.0 0.0 0.0 HOH
 4.267
 CB
 O
VAL B:91 B:113 0.0 0.0 H -60.8 -45.9 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 VAL C:85 H:113 0.0 0.0 H -68.3 -43.7 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 VAL A:85 A:113 0.0 0.0 H -56.6 -51.7 0.0 0.0 0.0 HOH
 4.149
 CB
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 VAL A:85 A:113 0.0 0.0 H -60.1 -45.2 0.0 0.0 0.0 GOL
HOH
 8.078
3.299
 HG13
HB
 H2
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 VAL B:201 B:113 4.0 0.026 H -96.0 -22.0 4.0 0.026 0.0
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 VAL A:81 A:114 0.0 0.0 H -64.9 -47.8 0.0 0.0 0.0 HOH
 4.053
 N
 H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 VAL A:93 A:114 0.0 0.0 H -58.4 -49.8 0.0 0.0 0.0 HOH
 4.149
 CB
 O
VAL B:93 B:114 0.0 0.0 H -60.9 -48.5 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 VAL B:89 H:114 0.0 0.0 H -65.2 -47.8 0.0 0.0 0.0
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 VAL A:77 A:114 0.0 0.0 H -65.6 -46.4 0.0 0.0 0.0 HOH
 4.318
 CB
 O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 VAL A:77 A:114 0.0 0.0 H -66.1 -47.9 0.0 0.0 0.0 HOH
 5.827
 N
 O
VAL B:77 B:114 0.0 0.0 H -66.4 -47.9 0.0 0.0 0.0 HOH
 5.684
 N
 O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 VAL A:79 A:114 0.0 0.0 H -69.3 -50.9 0.0 0.0 0.0 HOH
 4.008
 CB
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 VAL A:75 A:114 0.0 0.0 H -71.5 -60.8 0.0 0.0 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 VAL A:75 A:114 0.0 0.0 H -55.3 -59.3 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 VAL A:118 A:118 0.0 0.0 H -63.9 -46.9