Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219924961 . G A CCDS33380.1:NM_002181.3:c.229Cgc>Tgc_NP_002172.2:p.77R>C Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ARG A:62 B:77 68.0 0.302 G -72.4 -4.3 68.0 0.302 0.0 SO4
GOL
HOH
 6.566
3.244
2.985
 NH1
N
NE
 O2
C1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:62 B:77 67.0 0.298 G -71.7 -5.0 67.0 0.298 0.0 SO4
HOH
 6.559
3.020
 NH1
NE
 O2
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:62 B:77 73.0 0.324 G -71.5 -4.8 73.0 0.324 0.0 HOH
 2.965
 NH2
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 ARG A:62 B:77 68.0 0.302 G -68.4 -17.7 68.0 0.302 0.0 SO4
HOH
 6.697
3.113
 NH1
N
 O1
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:53 A:77 66.0 0.293 G -74.1 -11.1 66.0 0.293 0.0 HOH
 2.698
 HD3
 O
ARG B:53 B:77 87.0 0.387 G -65.8 -25.3 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:53 B:77 77.0 0.342 G -67.1 -18.5 77.0 0.342 0.0 HOH
 1.869
 HE
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:53 A:77 39.0 0.173 G -57.5 -23.9 39.0 0.173 0.0 HOH
 3.643
 NE
 O
ARG B:53 B:77 58.0 0.258 G -61.6 -7.5 NA NA NA
ARG C:53 C:77 68.0 0.302 G -70.4 -22.0 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:53 B:77 65.0 0.289 G -80.9 -6.2 65.0 0.289 0.0
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ARG B:52 B:72 146.0 0.649 G -80.3 13.8 146.0 0.649 0.0
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:49 C:72 68.0 0.302 G -70.1 -16.5 68.0 0.302 0.0
ARG F:49 F:72 67.0 0.298 G -70.1 -16.5 67.0 0.298 0.0
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:49 C:72 70.0 0.311 G -70.1 -16.5 70.0 0.311 0.0
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:49 C:72 68.0 0.302 G -70.1 -16.5 68.0 0.302 0.0
ARG F:49 F:72 67.0 0.298 G -70.1 -16.5 67.0 0.298 0.0
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ARG C:49 C:72 83.0 0.369 G -88.9 4.2 83.0 0.369 0.0
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ARG B:50 C:72 97.0 0.431 G -61.4 -18.3 97.0 0.431 0.0
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ARG B:50 C:72 72.0 0.32 H -53.4 -38.7 72.0 0.32 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ARG A:50 A:72 68.0 0.302 S -67.1 -22.7 68.0 0.302 0.0 HOH
 2.658
 NH2
 O
ARG B:50 B:72 55.0 0.244 G -79.4 -14.8 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ARG C:44 H:72 85.0 0.378 T -71.3 -11.1 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ARG A:44 A:72 80.0 0.356 G -75.7 -15.5 80.0 0.356 0.0 HOH
 2.964
 N
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ARG A:44 A:72 72.0 0.32 H -70.9 -29.6 72.0 0.32 0.0 HOH
 2.034
 HE
 O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ARG B:160 B:72 60.0 0.267 G -76.1 -6.2 60.0 0.267 0.0
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ARG A:40 A:73 50.0 0.222 G -68.8 -13.9 50.0 0.222 0.0 HOH
 2.561
 HH21
 O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ARG A:52 A:73 76.0 0.338 G -69.4 -20.9 76.0 0.338 0.0 HOH
 2.848
 NH2
 O
ARG B:52 B:73 76.0 0.338 G -64.2 -19.3 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ARG B:48 H:73 54.0 0.24 G -68.5 -15.9 54.0 0.24 0.0
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:36 A:73 48.0 0.213 T -100.0 0.4 48.0 0.213 0.0 HOH
 3.192
 NH2
 O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:36 A:73 59.0 0.262 G -80.5 -11.0 59.0 0.262 0.0 HOH
 6.968
 O
 O
ARG B:36 B:73 65.0 0.289 G -68.8 -12.1 65.0 0.289 0.0 HOH
 5.268
 NE
 O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ARG A:38 A:73 86.0 0.382 G -57.9 -26.2 86.0 0.382 0.0 HOH
 2.779
 N
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ARG A:34 A:73 85.0 0.378 G -74.5 1.5 85.0 0.378 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ARG A:34 A:73 103.0 0.458 G -70.4 -1.9 103.0 0.458 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ARG A:77 A:77 60.0 0.267 G -66.1 -17.7