Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219925018 . C A CCDS33380.1:NM_002181.3:c.172Gag>Tag_NP_002172.2:p.58E>* Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 GLU A:43 B:58 25.0 0.132 T -54.6 -43.3 25.0 0.132 0.0 ZN
SO4
HOH
 6.766
9.721
2.712
 OE2
C
OE1
 ZN
O2
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLU A:43 B:58 25.0 0.132 T -52.1 -43.4 25.0 0.132 0.0 ZN
SO4
HOH
 6.808
9.753
2.710
 OE2
C
OE1
 ZN
O2
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLU A:43 B:58 25.0 0.132 T -52.9 -46.5 25.0 0.132 0.0 ZN
HOH
 6.802
2.806
 OE2
OE1
 ZN
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLU A:43 B:58 25.0 0.132 T -54.5 -39.8 25.0 0.132 0.0 ZN
SO4
CO3
HOH
 6.860
9.722
4.669
2.695
 OE2
C
OE1
OE1
 ZN
O2
O3
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:34 A:58 26.0 0.137 T -46.4 -42.4 26.0 0.137 0.0 ZN
HOH
 6.800
2.135
 OE2
H
 ZN
O
GLU B:34 B:58 25.0 0.132 T -47.4 -47.4 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:34 B:58 28.0 0.147 T -52.7 -41.6 28.0 0.147 0.0 ZN
HOH
 6.683
2.046
 OE2
H
 ZN
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:34 A:58 23.0 0.121 T -61.6 -52.7 23.0 0.121 0.0 ZN
HOH
 6.662
2.754
 OE2
OE1
 ZN
O
GLU B:34 B:58 24.0 0.126 T -47.0 -44.5 NA NA NA
GLU C:34 C:58 27.0 0.142 T -51.3 -45.0 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:34 B:58 27.0 0.142 T -61.0 -37.0 27.0 0.142 0.0 ZN
 7.247
 OE2
 ZN
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 GLU B:33 B:53 27.0 0.142 T -67.3 -33.2 27.0 0.142 0.0 ZN
 7.890
 OE2
 ZN
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:30 C:53 25.0 0.132 T -77.2 -15.8 25.0 0.132 0.0 ZN
 9.845
 OE2
 ZN
GLU F:30 F:53 26.0 0.137 T -77.2 -15.7 26.0 0.137 0.0 ZN
 9.844
 OE2
 ZN
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:30 C:53 27.0 0.142 T -77.2 -15.7 27.0 0.142 0.0 ZN
 9.845
 OE2
 ZN
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:30 C:53 25.0 0.132 T -77.2 -15.8 25.0 0.132 0.0 ZN
 9.845
 OE2
 ZN
GLU F:30 F:53 26.0 0.137 T -77.2 -15.7 26.0 0.137 0.0 ZN
 9.844
 OE2
 ZN
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 GLU C:30 C:53 47.0 0.247 T -63.7 -31.0 47.0 0.247 0.0 ZN
 6.731
 OE2
 ZN
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 GLU B:31 C:53 43.0 0.226 T -65.4 -18.0 43.0 0.226 0.0
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 GLU B:31 C:53 47.0 0.247 S -74.2 -1.3 47.0 0.247 0.0 ZN
 7.276
 OE1
 ZN
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 GLU A:31 A:53 25.0 0.132 T -47.9 -50.8 25.0 0.132 0.0 ZN
HOH
 6.825
2.536
 OE2
OE1
 ZN
O
GLU B:31 B:53 17.0 0.089 T -50.8 -47.3 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 GLU C:25 H:53 24.0 0.126 T -56.1 -42.4 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 GLU A:25 A:53 26.0 0.137 T -47.9 -43.5 26.0 0.137 0.0 ZN
SO4
HOH
 6.680
4.773
2.804
 OE2
OE1
OE1
 ZN
O4
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 GLU A:25 A:53 21.0 0.111 T -53.4 -41.8 21.0 0.111 0.0 DMS
DMS
ZN
MG
HOH
 3.094
3.353
6.981
6.986
2.170
 OE1
H
OE2
OE2
H
 H23
H23
ZN
MG
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 GLU B:141 B:53 36.0 0.189 T -61.6 -47.2 36.0 0.189 0.0 ZN
 7.473
 OE2
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 GLU A:21 A:54 22.0 0.116 T -52.2 -47.1 22.0 0.116 0.0 ZN
HOH
 6.771
1.918
 OE2
OE1
 ZN
H1
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 GLU A:33 A:54 27.0 0.142 T -51.8 -42.1 27.0 0.142 0.0 ZN
HOH
 7.005
2.723
 OE2
OE1
 ZN
O
GLU B:33 B:54 30.0 0.158 T -50.6 -45.6 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 GLU B:29 H:54 38.0 0.2 T -54.0 -38.2 38.0 0.2 0.0 ZN
 6.790
 OE2
 ZN
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:17 A:54 29.0 0.153 T -54.8 -43.8 29.0 0.153 0.0 ZN
HOH
 6.749
2.723
 OE2
OE1
 ZN
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:17 A:54 26.0 0.137 T -54.3 -43.8 26.0 0.137 0.0 ZN
HOH
 6.738
2.738
 OE2
N
 ZN
O
GLU B:17 B:54 25.0 0.132 T -52.8 -46.3 25.0 0.132 0.0 ZN
HOH
 6.728
2.713
 OE2
N
 ZN
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 GLU A:19 A:54 23.0 0.121 T -40.4 -47.2 23.0 0.121 0.0 ZN
HOH
 6.913
6.868
 OE2
N
 ZN
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 GLU A:15 A:54 31.0 0.163 T -56.8 -41.7 31.0 0.163 0.0 ZN
 6.718
 OE2
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 GLU A:15 A:54 25.0 0.132 T -62.3 -34.1 25.0 0.132 0.0 ZN
 6.512
 OE2
 ZN

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 GLU A:58 A:58 30.0 0.158 T -47.8 -45.6