Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 232597709 . C A CCDS33398.1:NM_002601.2:c.406Gac>Tac_NP_002592.1:p.136D>Y Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7qjk 1 O43924 100.0 2e-110 X-RAY
 2022-01-26 ASP A:137 BBB:136 71.0 0.473 T 61.7 -97.1 71.0 0.473 0.0
ASP B:137 AAA:136 73.0 0.487 T 58.7 -97.1 NA NA NA
ASP C:137 CCC:136 55.0 0.367 T 57.1 -94.7 NA NA NA
ASP D:137 DDD:136 85.0 0.567 T 35.6 61.0 NA NA NA
1ksg 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ASP B:138 B:136 96.0 0.64 T 61.6 -108.6 96.0 0.64 0.0 HOH
 7.435
 O
 O
1ksh 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ASP B:138 B:136 79.0 0.527 T 68.5 -103.1 79.0 0.527 0.0 HOH
 3.043
 OD1
 O
1ksj 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ASP B:138 B:136 84.0 0.56 T 68.2 -94.7 84.0 0.56 0.0 HOH
 5.328
 CB
 O
3t5g 2 O43924 100.0 2e-110 X-RAY
 2011-10-26 ASP B:138 B:136 72.0 0.48 T 59.7 -116.7 72.0 0.48 0.0 HOH
 3.686
 CB
 O
3t5i 1 O43924 100.0 2e-110 X-RAY
 2011-11-02 ASP A:138 B:136 71.0 0.473 T 57.2 -114.8 NA NA NA
ASP B:138 A:136 78.0 0.52 T 61.3 -114.1 78.0 0.52 0.0 HOH
 2.817
 OD1
 O
ASP C:138 C:136 75.0 0.5 T 63.6 -118.4 NA NA NA
ASP D:138 D:136 81.0 0.54 T 61.9 -119.5 NA NA NA
4jhp 1 O43924 100.0 2e-110 X-RAY
 2013-04-17 ASP A:138 B:136 60.0 0.4 T 60.0 -103.1 60.0 0.4 0.0 HOH
 2.765
 OD1
 O
4jv6 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ASP A:138 B:136 72.0 0.48 T 53.7 -112.2 72.0 0.48 0.0 HOH
 2.621
 OD1
 O
4jv8 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ASP A:138 B:136 82.0 0.547 T 59.5 -114.8 82.0 0.547 0.0 HOH
 2.609
 OD1
 O
4jvb 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ASP A:138 B:136 81.0 0.54 T 61.0 -114.4 81.0 0.54 0.0 HOH
 2.720
 OD1
 O
4jvf 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ASP A:138 B:136 74.0 0.493 T 52.4 -114.4 74.0 0.493 0.0 HOH
 5.952
 OD2
 O
5nal 1 O43924 100.0 3e-110 X-RAY
 2017-05-10 ASP A:136 B:136 78.0 0.52 T 60.2 -108.8 78.0 0.52 0.0 HOH
 6.721
 O
 O
5tb5 2 O43924 100.0 3e-110 X-RAY
 2016-11-02 ASP B:136 B:136 68.0 0.453 T 57.6 -116.6 68.0 0.453 0.0 HOH
 5.065
 CB
 O
ASP D:136 D:136 68.0 0.453 T 45.7 -117.1 NA NA NA
5x72 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ASP A:136 A:136 80.0 0.533 T 57.2 -113.3 80.0 0.533 0.0 HOH
 3.193
 OD2
 O
5x73 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ASP A:136 A:136 73.0 0.487 T 55.0 -110.9 73.0 0.487 0.0 HOH
 3.143
 OD1
 O
5yav 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ASP A:136 B:136 72.0 0.48 T 54.5 -100.0 72.0 0.48 0.0 HOH
 6.818
 O
 O
5yaw 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ASP A:136 B:136 82.0 0.547 T 58.0 -113.6 82.0 0.547 0.0 HOH
 2.629
 OD2
 O
7q9r 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ASP A:136 BBB:136 74.0 0.493 T 55.3 -113.7 74.0 0.493 0.0 HOH
 3.207
 C
 O
7q9s 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ASP A:136 BBB:136 81.0 0.54 T 59.8 -116.0 81.0 0.54 0.0 HOH
 2.713
 OD2
 O
ASP B:136 AAA:136 81.0 0.54 T 59.8 -113.0 NA NA NA
7q9u 2 O43924 100.0 3e-110 X-RAY
 2022-01-26 ASP C:136 DDD:136 77.0 0.513 T 62.3 -104.2 NA NA NA
ASP D:136 CCC:136 69.0 0.46 T 61.8 -104.1 NA NA NA
5x74 1 O43924 99.33 9e-110 X-RAY
 2017-10-04 ASP A:136 A:136 68.0 0.453 T 57.4 -113.9 68.0 0.453 0.0 HOH
 6.790
 O
 O
5e8f 1 O43924 100.0 2e-109 X-RAY
 2015-11-18 ASP A:135 A:136 74.0 0.493 T 59.1 -105.0 74.0 0.493 0.0 HOH
 3.509
 CB
 O
ASP B:135 C:136 70.0 0.467 T 55.2 -106.6 NA NA NA
5f2u 1 O43924 100.0 2e-109 X-RAY
 2016-04-13 ASP A:135 A:136 74.0 0.493 T 57.6 -104.8 74.0 0.493 0.0 HOH
 4.578
 CB
 O
ASP B:135 B:136 78.0 0.52 T 56.9 -106.5 NA NA NA
5ml2 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ASP A:135 B:136 78.0 0.52 T 58.4 -113.4 78.0 0.52 0.0 HOH
 2.790
 OD1
 O
5ml3 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ASP A:135 B:136 76.0 0.507 T 59.7 -114.8 76.0 0.507 0.0 HOH
 2.773
 OD1
 O
5ml4 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ASP A:135 B:136 76.0 0.507 T 57.9 -110.0 76.0 0.507 0.0 HOH
 6.674
 O
 O
5ml6 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ASP A:135 B:136 70.0 0.467 T 61.6 -112.2 70.0 0.467 0.0 HOH
 2.352
 OD1
 O
5ml8 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ASP A:135 B:136 77.0 0.513 T 56.6 -111.9 77.0 0.513 0.0 HOH
 6.831
 O
 O
7q9q 1 O43924 100.0 2e-109 X-RAY
 2022-01-19 ASP A:139 BBB:136 74.0 0.493 T 68.3 -109.5 74.0 0.493 0.0 HOH
 2.205
 OD2
 O
5t4x 1 O55057 98.0 3e-109 X-RAY
 2018-01-10 ASP A:156 A:136 74.0 0.493 T 60.1 -109.0 74.0 0.493 0.0 HOH
 2.677
 OD2
 O
5tar 2 O43924 100.0 7e-109 X-RAY
 2016-11-02 ASP B:134 B:136 83.0 0.553 T 61.9 -117.2 83.0 0.553 0.0 HOH
 6.830
 O
 O
5e80 1 O43924 99.33 1e-108 X-RAY
 2016-05-04 ASP A:135 B:136 76.0 0.507 T 57.8 -121.7 76.0 0.507 0.0 HOH
 3.708
 CB
 O
ASP B:135 A:136 81.0 0.54 T 59.9 -98.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o43924-f1 1 O43924 100.0 1e-110 ASP A:136 A:136 61.0 0.407 T 53.8 -114.5