Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 232602765 . G A CCDS33398.1:NM_002601.2:c.223Cgc>Tgc_NP_002592.1:p.75R>C Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7qjk 1 O43924 100.0 2e-110 X-RAY
 2022-01-26 ARG A:76 BBB:75 30.0 0.133 E -147.7 161.2 30.0 0.133 0.0 9VO
SO4
HOH
 9.663
8.983
8.157
 C
NH2
CA
 C13
O1
O
ARG B:76 AAA:75 37.0 0.164 E -155.5 151.7 NA NA NA
ARG C:76 CCC:75 41.0 0.182 E -157.3 153.6 NA NA NA
ARG D:76 DDD:75 39.0 0.173 E -162.8 162.4 NA NA NA
1ksg 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:77 B:75 58.0 0.258 E -142.2 175.4 58.0 0.258 0.0 HOH
 2.673
 NH1
 O
1ksh 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:77 B:75 43.0 0.191 E -157.8 165.2 43.0 0.191 0.0 HOH
 3.043
 NH2
 O
1ksj 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:77 B:75 53.0 0.236 E -149.0 162.3 53.0 0.236 0.0 HOH
 2.775
 CD
 O
3t5g 2 O43924 100.0 2e-110 X-RAY
 2011-10-26 ARG B:77 B:75 34.0 0.151 E -155.7 162.4 34.0 0.151 0.0 FAR
HOH
 9.549
2.797
 O
NH2
 C14
O
3t5i 1 O43924 100.0 2e-110 X-RAY
 2011-11-02 ARG A:77 B:75 48.0 0.213 E -151.0 164.7 NA NA NA
ARG B:77 A:75 38.0 0.169 E -155.8 160.9 38.0 0.169 0.0 FAR
HOH
 9.486
3.032
 O
NH1
 C15
O
ARG C:77 C:75 35.0 0.156 E -153.4 162.3 NA NA NA
ARG D:77 D:75 49.0 0.218 E -156.6 162.9 NA NA NA
4jhp 1 O43924 100.0 2e-110 X-RAY
 2013-04-17 ARG A:77 B:75 41.0 0.182 E -150.2 160.8 41.0 0.182 0.0 HOH
 2.959
 NH1
 O
4jv6 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:77 B:75 49.0 0.218 E -156.3 165.5 49.0 0.218 0.0 18F
HOH
 9.348
2.909
 C
NH1
 CAF
O
4jv8 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:77 B:75 36.0 0.16 E -155.5 167.9 36.0 0.16 0.0 1M1
HOH
 9.808
2.790
 O
NH1
 CAL
O
4jvb 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:77 B:75 47.0 0.209 E -152.5 168.1 47.0 0.209 0.0 1M0
HOH
 9.377
2.672
 O
NH2
 CBD
O
4jvf 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:77 B:75 52.0 0.231 E -153.7 170.8 52.0 0.231 0.0 17X
HOH
 9.449
2.808
 O
NH1
 CAW
O
5nal 1 O43924 100.0 3e-110 X-RAY
 2017-05-10 ARG A:75 B:75 27.0 0.12 E -156.8 166.3 27.0 0.12 0.0 8RQ
HOH
 8.918
2.771
 O
NH1
 CL1
O
5tb5 2 O43924 100.0 3e-110 X-RAY
 2016-11-02 ARG B:75 B:75 41.0 0.182 E -155.4 161.3 41.0 0.182 0.0 FAR
EDO
HOH
 6.674
7.763
3.122
 O
C
NH1
 C14
C2
O
ARG D:75 D:75 20.0 0.089 E -161.0 164.2 NA NA NA
5x72 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ARG A:75 A:75 36.0 0.16 E -151.1 165.2 36.0 0.16 0.0 P59
HOH
 9.792
2.777
 O
NH1
 CAB
O
5x73 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ARG A:75 A:75 46.0 0.204 E -154.4 158.4 46.0 0.204 0.0 P59
HOH
 9.982
4.409
 O
NH2
 CAB
O
5yav 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ARG A:75 B:75 59.0 0.262 E -157.3 167.3 59.0 0.262 0.0 8SF
HOH
 8.859
2.853
 O
NH1
 H9
O
5yaw 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ARG A:75 B:75 32.0 0.142 E -157.1 157.8 32.0 0.142 0.0 8SL
HOH
 6.299
3.106
 O
NH1
 C26
O
7q9r 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ARG A:75 BBB:75 36.0 0.16 E -146.5 162.8 36.0 0.16 0.0 EDO
SO4
SO4
HOH
 6.098
7.430
9.702
2.761
 O
CB
N
NH1
 O1
O1
O2
O
7q9s 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ARG A:75 BBB:75 51.0 0.227 E -151.6 163.9 51.0 0.227 0.0 9TI
EDO
EDO
FAR
HOH
 8.683
7.797
9.602
9.428
2.915
 C
CB
N
O
NH1
 C8
C1
O2
C14
O
ARG B:75 AAA:75 48.0 0.213 E -149.5 164.4 NA NA NA
7q9u 2 O43924 100.0 3e-110 X-RAY
 2022-01-26 ARG C:75 DDD:75 35.0 0.156 E -152.7 162.8 NA NA NA
ARG D:75 CCC:75 35.0 0.156 E -154.0 159.8 NA NA NA
5x74 1 O43924 99.33 9e-110 X-RAY
 2017-10-04 ARG A:75 A:75 38.0 0.169 E -154.1 161.2 38.0 0.169 0.0 JAY
HOH
 9.778
2.726
 O
NH1
 CAB
O
5e8f 1 O43924 100.0 2e-109 X-RAY
 2015-11-18 ARG A:74 A:75 38.0 0.169 E -157.5 161.4 38.0 0.169 0.0 GER
HOH
 6.696
2.892
 O
NH1
 C20
O
ARG B:74 C:75 35.0 0.156 E -147.3 166.5 NA NA NA
5f2u 1 O43924 100.0 2e-109 X-RAY
 2016-04-13 ARG A:74 A:75 46.0 0.204 E -148.8 167.5 46.0 0.204 0.0 HOH
 2.912
 NH1
 O
ARG B:74 B:75 43.0 0.191 E -151.9 164.0 NA NA NA
5ml2 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:74 B:75 37.0 0.164 E -154.5 164.2 37.0 0.164 0.0 NH6
HOH
 9.045
2.879
 O
NH1
 CL
O
5ml3 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:74 B:75 44.0 0.196 E -154.6 166.4 44.0 0.196 0.0 DL3
HOH
 8.835
2.879
 O
NH1
 CL
O
5ml4 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:74 B:75 45.0 0.2 E -151.5 167.3 45.0 0.2 0.0 RRQ
HOH
 8.901
2.758
 O
NH1
 CL
O
5ml6 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:74 B:75 30.0 0.133 E -154.8 165.7 30.0 0.133 0.0 9GD
HOH
 8.868
2.814
 O
NH1
 CL
O
5ml8 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:74 B:75 36.0 0.16 E -157.5 166.7 36.0 0.16 0.0 V98
HOH
 9.130
2.908
 O
NH1
 CL
O
7q9q 1 O43924 100.0 2e-109 X-RAY
 2022-01-19 ARG A:78 BBB:75 51.0 0.227 E -157.4 158.9 51.0 0.227 0.0 EDO
GER
EDO
EDO
HOH
 7.865
6.568
8.787
9.134
2.974
 C
O
NH1
O
NH1
 C2
C19
O1
O2
O
5t4x 1 O55057 98.0 3e-109 X-RAY
 2018-01-10 ARG A:95 A:75 38.0 0.169 E -144.6 162.8 38.0 0.169 0.0 HOH
 4.402
 NH2
 O
5tar 2 O43924 100.0 7e-109 X-RAY
 2016-11-02 ARG B:73 B:75 39.0 0.173 E -156.8 166.5 39.0 0.173 0.0 FAR
EDO
HOH
 9.824
7.770
2.804
 O
C
NH1
 C14
C1
O
5e80 1 O43924 99.33 1e-108 X-RAY
 2016-05-04 ARG A:74 B:75 44.0 0.196 E -156.4 170.5 44.0 0.196 0.0 5KP
HOH
 9.570
9.095
 O
NE
 CAQ
O
ARG B:74 A:75 42.0 0.187 E -153.7 163.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o43924-f1 1 O43924 100.0 1e-110 ARG A:75 A:75 45.0 0.2 E -149.9 158.0