Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 232602771 . T A CCDS33398.1:NM_002601.2:c.217Aaa>Taa_NP_002592.1:p.73K>* Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7qjk 1 O43924 100.0 2e-110 X-RAY
 2022-01-26 LYS A:74 BBB:73 19.0 NA E -139.8 99.6 19.0 NA NA
LYS B:74 AAA:73 66.0 0.33 E -140.5 90.2 NA NA NA
LYS C:74 CCC:73 68.0 0.34 E -141.2 90.9 NA NA NA
LYS D:74 DDD:73 81.0 0.405 E -137.2 85.8 NA NA NA
1ksg 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 LYS B:75 B:73 112.0 0.56 E -139.0 48.0 112.0 0.56 0.0 HOH
 7.108
 N
 O
1ksh 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 LYS B:75 B:73 111.0 0.555 E -129.6 52.9 111.0 0.555 0.0 HOH
 3.931
 CA
 O
1ksj 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 LYS B:75 B:73 103.0 0.515 E -132.4 56.9 103.0 0.515 0.0 HOH
 3.425
 CG
 O
3t5g 2 O43924 100.0 2e-110 X-RAY
 2011-10-26 LYS B:75 B:73 64.0 0.32 E -143.7 73.3 64.0 0.32 0.0 HOH
 3.639
 CA
 O
3t5i 1 O43924 100.0 2e-110 X-RAY
 2011-11-02 LYS A:75 B:73 76.0 0.38 E -147.7 78.1 NA NA NA
LYS B:75 A:73 87.0 0.435 E -149.2 70.8 87.0 0.435 0.0 HOH
 3.843
 CD
 O
LYS C:75 C:73 80.0 0.4 E -151.8 73.7 NA NA NA
LYS D:75 D:73 88.0 0.44 E -141.8 68.8 NA NA NA
4jhp 1 O43924 100.0 2e-110 X-RAY
 2013-04-17 LYS A:75 B:73 71.0 0.355 E -140.7 79.4 71.0 0.355 0.0 HOH
 3.425
 NZ
 O
4jv6 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 LYS A:75 B:73 82.0 0.41 E -142.8 72.0 82.0 0.41 0.0 HOH
 3.661
 CD
 O
4jv8 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 LYS A:75 B:73 76.0 0.38 E -148.7 71.7 76.0 0.38 0.0 HOH
 2.676
 CG
 O
4jvb 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 LYS A:75 B:73 87.0 0.435 E -144.4 76.1 87.0 0.435 0.0 HOH
 3.387
 CE
 O
4jvf 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 LYS A:75 B:73 92.0 0.46 E -141.8 74.3 92.0 0.46 0.0 HOH
 2.434
 NZ
 O
5nal 1 O43924 100.0 3e-110 X-RAY
 2017-05-10 LYS A:73 B:73 82.0 0.41 E -138.3 72.3 82.0 0.41 0.0 HOH
 6.494
 CA
 O
5tb5 2 O43924 100.0 3e-110 X-RAY
 2016-11-02 LYS B:73 B:73 103.0 0.515 E -144.9 67.0 103.0 0.515 0.0 HOH
 4.041
 CE
 O
LYS D:73 D:73 111.0 0.555 E -135.9 75.4 NA NA NA
5x72 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 LYS A:73 A:73 70.0 0.35 E -150.3 75.7 70.0 0.35 0.0 HOH
 6.671
 CA
 O
5x73 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 LYS A:73 A:73 79.0 0.395 E -141.4 88.1 79.0 0.395 0.0 HOH
 7.443
 CD
 O
5yav 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 LYS A:73 B:73 101.0 0.505 E -142.3 72.7 101.0 0.505 0.0 HOH
 7.360
 O
 O
5yaw 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 LYS A:73 B:73 80.0 0.4 E -153.9 77.7 80.0 0.4 0.0 HOH
 2.892
 NZ
 O
7q9r 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 LYS A:73 BBB:73 94.0 0.47 E -137.8 77.8 94.0 0.47 0.0 SO4
HOH
 6.199
4.854
 CA
CD
 O2
O
7q9s 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 LYS A:73 BBB:73 76.0 0.38 E -147.3 73.5 76.0 0.38 0.0 EDO
HOH
 4.621
2.732
 NZ
NZ
 O2
O
LYS B:73 AAA:73 74.0 0.37 E -147.0 75.3 NA NA NA
7q9u 2 O43924 100.0 3e-110 X-RAY
 2022-01-26 LYS C:73 DDD:73 91.0 0.455 E -129.9 69.5 NA NA NA
LYS D:73 CCC:73 99.0 0.495 E -129.9 69.6 NA NA NA
5x74 1 O43924 99.33 9e-110 X-RAY
 2017-10-04 LYS A:73 A:73 72.0 0.36 E -148.4 76.4 72.0 0.36 0.0 HOH
 7.293
 CE
 O
5e8f 1 O43924 100.0 2e-109 X-RAY
 2015-11-18 LYS A:72 A:73 82.0 0.41 E -154.8 80.3 82.0 0.41 0.0 HOH
 4.933
 N
 O
LYS B:72 C:73 75.0 0.375 E -149.1 74.8 NA NA NA
5f2u 1 O43924 100.0 2e-109 X-RAY
 2016-04-13 LYS A:72 A:73 73.0 0.365 E -152.2 77.2 73.0 0.365 0.0 HOH
 6.464
 CA
 O
LYS B:72 B:73 68.0 0.34 E -145.2 76.1 NA NA NA
5ml2 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 LYS A:72 B:73 91.0 0.455 E -152.2 74.9 91.0 0.455 0.0 HOH
 3.439
 CE
 O
5ml3 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 LYS A:72 B:73 75.0 0.375 E -146.0 68.7 75.0 0.375 0.0 HOH
 3.086
 CE
 O
5ml4 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 LYS A:72 B:73 75.0 0.375 E -137.2 78.7 75.0 0.375 0.0 HOH
 6.792
 CA
 O
5ml6 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 LYS A:72 B:73 81.0 0.405 E -144.9 76.5 81.0 0.405 0.0 HOH
 4.108
 NZ
 O
5ml8 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 LYS A:72 B:73 82.0 0.41 E -134.6 70.6 82.0 0.41 0.0 HOH
 6.882
 CA
 O
7q9q 1 O43924 100.0 2e-109 X-RAY
 2022-01-19 LYS A:76 BBB:73 75.0 0.375 E -147.9 77.9 75.0 0.375 0.0 HOH
 2.798
 NZ
 O
5t4x 1 O55057 98.0 3e-109 X-RAY
 2018-01-10 LYS A:93 A:73 90.0 0.45 E -141.1 74.1 90.0 0.45 0.0 HOH
 4.238
 CD
 O
5tar 2 O43924 100.0 7e-109 X-RAY
 2016-11-02 LYS B:71 B:73 104.0 0.52 E -136.4 65.5 104.0 0.52 0.0 HOH
 7.191
 O
 O
5e80 1 O43924 99.33 1e-108 X-RAY
 2016-05-04 LYS A:72 B:73 85.0 0.425 E -139.0 77.9 85.0 0.425 0.0 HOH
 5.390
 N
 O
LYS B:72 A:73 89.0 0.445 E -134.6 76.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o43924-f1 1 O43924 100.0 1e-110 LYS A:73 A:73 93.0 0.465 E -139.8 68.9