Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 232603881 . C A CCDS33398.1:NM_002601.2:c.68cGg>cTg_NP_002592.1:p.23R>L Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7qjk 1 O43924 100.0 2e-110 X-RAY
 2022-01-26 ARG A:24 BBB:23 73.0 0.324 E -116.3 140.2 73.0 0.324 0.0 9VO
HOH
 9.680
9.227
 N
N
 C2
O
ARG B:24 AAA:23 72.0 0.32 E -116.9 142.0 NA NA NA
ARG C:24 CCC:23 3.0 NA E -120.9 132.8 NA NA NA
ARG D:24 DDD:23 14.0 NA E -122.4 145.8 NA NA NA
1ksg 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:25 B:23 54.0 0.24 E -115.0 162.9 4.0 0.018 0.222 A:Q9D0J4:0.222
 HOH
 2.685
 NH1
 O
1ksh 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:25 B:23 57.0 0.253 E -119.9 157.5 16.0 0.071 0.182 A:Q9D0J4:0.182
 HOH
 2.856
 NH2
 O
1ksj 2 O43924 100.0 2e-110 X-RAY
 2002-05-08 ARG B:25 B:23 62.0 0.276 E -119.2 157.9 14.0 0.062 0.214 A:Q9D0J4:0.213
 HOH
 2.799
 NH2
 O
3t5g 2 O43924 100.0 2e-110 X-RAY
 2011-10-26 ARG B:25 B:23 65.0 0.289 E -123.8 147.3 65.0 0.289 0.0 FAR
HOH
 7.484
3.178
 N
CD
 C1
O
3t5i 1 O43924 100.0 2e-110 X-RAY
 2011-11-02 ARG A:25 B:23 67.0 0.298 E -121.1 148.8 NA NA NA
ARG B:25 A:23 62.0 0.276 E -119.2 152.8 62.0 0.276 0.0 FAR
HOH
 7.445
2.566
 N
NH2
 C1
O
ARG C:25 C:23 60.0 0.267 E -128.8 145.8 NA NA NA
ARG D:25 D:23 62.0 0.276 E -123.0 152.0 NA NA NA
4jhp 1 O43924 100.0 2e-110 X-RAY
 2013-04-17 ARG A:25 B:23 74.0 0.329 E -118.3 147.2 74.0 0.329 0.0 HOH
 3.385
 CG
 O
4jv6 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:25 B:23 69.0 0.307 E -129.9 147.1 69.0 0.307 0.0 18F
18F
HOH
 8.965
7.460
3.105
 N
O
CD
 CAN
CAT
O
4jv8 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:25 B:23 65.0 0.289 E -126.1 151.2 65.0 0.289 0.0 1M1
1M1
HOH
 8.541
7.541
2.710
 N
O
NH1
 CAF
CAH
O
4jvb 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:25 B:23 57.0 0.253 E -125.9 149.0 57.0 0.253 0.0 1M0
HOH
 7.481
3.016
 O
NH1
 CBQ
O
4jvf 1 O43924 100.0 2e-110 X-RAY
 2013-05-22 ARG A:25 B:23 64.0 0.284 E -125.5 150.9 64.0 0.284 0.0 17X
HOH
 7.661
9.166
 N
C
 CAZ
O
5nal 1 O43924 100.0 3e-110 X-RAY
 2017-05-10 ARG A:23 B:23 68.0 0.302 E -129.8 150.5 68.0 0.302 0.0 8RQ
HOH
 7.942
5.904
 O
NH1
 CBM
O
5tb5 2 O43924 100.0 3e-110 X-RAY
 2016-11-02 ARG B:23 B:23 71.0 0.316 E -117.7 148.4 71.0 0.316 0.0 FAR
EDO
HOH
 9.212
9.517
3.683
 N
N
CD
 C1
O1
O
ARG D:23 D:23 69.0 0.307 E -131.5 144.1 NA NA NA
5x72 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ARG A:23 A:23 71.0 0.316 E -138.4 143.6 71.0 0.316 0.0 P59
P69
HOH
 8.521
7.438
3.327
 N
O
NH1
 CAQ
CAU
O
5x73 1 O43924 100.0 3e-110 X-RAY
 2017-10-04 ARG A:23 A:23 61.0 0.271 E -139.8 147.8 61.0 0.271 0.0 P59
P59
 8.525
8.473
 N
O
 CAV
CAT
5yav 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ARG A:23 B:23 64.0 0.284 E -127.6 149.7 64.0 0.284 0.0 8SF
HOH
 8.105
7.114
 N
NH2
 H8
O
5yaw 1 O43924 100.0 3e-110 X-RAY
 2018-09-05 ARG A:23 B:23 68.0 0.302 E -126.2 157.0 68.0 0.302 0.0 8SL
HOH
 9.337
3.450
 N
CD
 C07
O
7q9r 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ARG A:23 BBB:23 76.0 0.338 E -122.2 145.4 76.0 0.338 0.0 FAR
HOH
 8.315
3.488
 O
NH2
 C4
O
7q9s 1 O43924 100.0 3e-110 X-RAY
 2022-01-19 ARG A:23 BBB:23 75.0 0.333 E -122.6 132.4 75.0 0.333 0.0 9TI
FAR
HOH
 7.276
7.838
3.689
 N
N
NH1
 C13
C4
O
ARG B:23 AAA:23 67.0 0.298 E -117.0 130.8 NA NA NA
7q9u 2 O43924 100.0 3e-110 X-RAY
 2022-01-26 ARG C:23 DDD:23 73.0 0.324 E -114.2 156.3 NA NA NA
ARG D:23 CCC:23 70.0 0.311 E -112.3 154.7 NA NA NA
5x74 1 O43924 99.33 9e-110 X-RAY
 2017-10-04 ARG A:23 A:23 57.0 0.253 E -131.9 149.1 57.0 0.253 0.0 JAY
HOH
 8.114
6.610
 O
O
 CBI
O
5e8f 1 O43924 100.0 2e-109 X-RAY
 2015-11-18 ARG A:22 A:23 69.0 0.307 E -134.7 137.3 69.0 0.307 0.0 GER
HOH
 7.401
4.682
 N
NH1
 C1
O
ARG B:22 C:23 69.0 0.307 E -119.8 140.9 NA NA NA
5f2u 1 O43924 100.0 2e-109 X-RAY
 2016-04-13 ARG A:22 A:23 69.0 0.307 E -115.2 133.2 69.0 0.307 0.0 HOH
 4.760
 NH1
 O
ARG B:22 B:23 71.0 0.316 E -116.7 135.1 NA NA NA
5ml2 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:22 B:23 77.0 0.342 E -130.8 149.8 77.0 0.342 0.0 NH6
HOH
 8.284
3.404
 N
CD
 CAN
O
5ml3 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:22 B:23 62.0 0.276 E -132.9 151.4 62.0 0.276 0.0 DL3
HOH
 7.999
2.718
 O
NH1
 CAK
O
5ml4 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:22 B:23 69.0 0.307 E -128.3 151.8 69.0 0.307 0.0 RRQ
HOH
 8.252
3.277
 N
NH1
 CAG
O
5ml6 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:22 B:23 63.0 0.28 E -132.5 149.4 63.0 0.28 0.0 9GD
HOH
 8.298
5.544
 N
NH2
 CAU
O
5ml8 1 O43924 100.0 2e-109 X-RAY
 2017-02-01 ARG A:22 B:23 63.0 0.28 E -130.8 152.6 63.0 0.28 0.0 V98
HOH
 8.363
9.794
 O
N
 CAK
O
7q9q 1 O43924 100.0 2e-109 X-RAY
 2022-01-19 ARG A:26 BBB:23 69.0 0.307 E -118.2 143.5 69.0 0.307 0.0 CMT
EDO
GER
HOH
 8.750
9.378
7.769
2.643
 O
N
O
NE
 SG
O1
C1
O
5t4x 1 O55057 98.0 3e-109 X-RAY
 2018-01-10 ARG A:43 A:23 81.0 0.36 E -123.8 155.0 81.0 0.36 0.0 HOH
 2.989
 NH1
 O
5tar 2 O43924 100.0 7e-109 X-RAY
 2016-11-02 ARG B:21 B:23 63.0 0.28 E -121.3 153.8 63.0 0.28 0.0 FAR
EDO
HOH
 8.480
9.476
3.245
 O
N
NH1
 C1
O2
O
5e80 1 O43924 99.33 1e-108 X-RAY
 2016-05-04 ARG A:22 B:23 71.0 0.316 E -120.7 153.6 71.0 0.316 0.0 5KP
HOH
 7.890
2.768
 O
NE
 CAU
O
ARG B:22 A:23 66.0 0.293 E -126.1 149.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o43924-f1 1 O43924 100.0 1e-110 ARG A:23 A:23 77.0 0.342 E -121.4 148.1