Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808427 . A C CCDS2543.1:NM_000030.2:c.145Atg>Ctg_NP_000021.1:p.49M>L Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 MET A:49 A:49 77.0 0.416 T -129.5 18.9 71.0 0.384 0.032 A:P21549:0.032
 PLP
AOA
GOL
HOH
 8.776
6.125
5.581
2.988
 SD
SD
O
N
 O1P
O3
C3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 MET A:49 A:49 74.0 0.4 T -126.6 22.9 63.0 0.341 0.059 A:P21549:0.059
 PLP
HOH
 8.737
6.965
 SD
SD
 O3P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 MET A:49 A:49 77.0 0.416 T -134.3 39.0 57.0 0.308 0.108 A:P21549:0.108
 PMP
HOH
 8.617
9.702
 SD
O
 O1P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 MET A:49 A:49 77.0 0.416 T -134.9 33.8 77.0 0.416 0.0 PLP
 8.601
 SD
 O3P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 MET A:51 A:49 75.0 0.405 T -134.9 22.8 49.0 0.265 0.14 C:P21549:0.141
 HOH
 2.745
 N
 O
MET C:51 C:49 77.0 0.416 T -134.0 26.0 51.0 0.276 0.14 A:P21549:0.141
 BTB
HOH
 8.380
2.683
 CE
N
 O8
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 MET A:49 A:49 76.0 0.411 T -131.2 45.4 52.0 0.281 0.13 A:P21549:0.13
 PLP
DIO
HOH
 8.509
4.481
4.574
 SD
SD
CG
 O1P
C1
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 MET A:51 A:49 75.0 0.405 T -133.4 26.8 58.0 0.314 0.091 B:P21549:0.092
 SO4
BTB
BME
HOH
 8.243
9.818
5.537
2.858
 SD
CE
SD
N
 O2
O4
O1
O
MET B:51 C:49 76.0 0.411 T -130.9 23.3 57.0 0.308 0.103 A:P21549:0.103
 SO4
BME
BTB
HOH
 8.508
5.674
7.851
2.895
 SD
CE
CE
N
 O1
C2
O6
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 MET A:51 A:49 81.0 0.438 T -137.5 19.7 57.0 0.308 0.13 B:P21549:0.13
 GOL
 3.210
 SD
 O1
MET B:51 B:49 82.0 0.443 T -138.5 19.5 64.0 0.346 0.097 A:P21549:0.097
 GOL
GOL
 4.418
8.800
 SD
O
 C2
O1
MET C:51 C:49 80.0 0.432 T -137.5 21.1 NA NA NA
MET D:51 D:49 82.0 0.443 T -140.3 22.1 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 MET A:49 A:49 76.0 0.411 T -138.9 27.2 76.0 0.411 0.0 HOH
 2.985
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 MET A:60 A:49 79.0 0.427 T -125.1 27.1 56.0 0.303 0.124 B:P21549:0.124
 BTB
PLP
HOH
 9.779
8.489
2.729
 CE
SD
O
 O3
O2P
O
MET B:60 B:49 76.0 0.411 T -123.8 23.6 52.0 0.281 0.13 A:P21549:0.13
 PLP
BTB
HOH
 8.581
9.778
2.548
 SD
CE
O
 O1P
O4
O
MET C:60 E:49 77.0 0.416 T -125.9 27.1 NA NA NA
MET D:60 G:49 76.0 0.411 T -122.0 20.0 NA NA NA
MET E:60 M:49 77.0 0.416 T -123.3 29.3 NA NA NA
MET F:60 N:49 76.0 0.411 T -122.4 26.8 NA NA NA
MET G:60 S:49 77.0 0.416 T -127.5 27.4 NA NA NA
MET H:60 T:49 75.0 0.405 T -121.6 22.6 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 MET A:51 A:49 72.0 0.389 T -124.3 24.2 46.0 0.249 0.14 B:P21549:0.141
 SO4
HOH
 8.424
5.973
 SD
O
 O4
O
MET B:51 C:49 74.0 0.4 T -136.8 26.3 49.0 0.265 0.135 A:P21549:0.135
 SO4
BME
HOH
 8.609
6.630
6.302
 SD
SD
SD
 O2
S2
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 MET A:49 A:49 73.0 0.395 T -136.6 12.6 52.0 0.281 0.114 A:P21549:0.114
 PLP
GOL
HOH
 8.721
4.559
3.120
 SD
SD
N
 O2P
O3
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 MET A:49 A:49 64.0 0.346 T -119.5 20.9 52.0 0.281 0.065 A:P21549:0.065
 PLP
HOH
 8.704
2.959
 SD
O
 O1P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 MET A:44 A:49 78.0 0.422 T -126.7 23.6 56.0 0.303 0.119 B:P21549:0.119
 PLP
HOH
 8.078
1.974
 HG3
H
 O2P
O
MET B:44 B:49 72.0 0.389 T -127.5 27.7 48.0 0.259 0.13 A:P21549:0.13
 PLP
HOH
 7.929
1.991
 HG3
H
 O1P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 MET A:44 A:49 78.0 0.422 T -128.4 24.0 55.0 0.297 0.125 B:P21549:0.124
 PLR
HOH
 8.073
2.059
 HG3
H
 O3P
O
MET B:44 B:49 74.0 0.4 T -128.5 28.4 48.0 0.259 0.141 A:P21549:0.141
 PLR
HOH
 8.031
2.078
 HG3
H
 O1P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 MET A:49 A:49 76.0 0.411 T -131.1 29.0 54.0 0.292 0.119 B:P21549:0.119
 BTB
GOL
PLP
HOH
 9.260
4.623
8.423
2.592
 CE
O
SD
O
 O1
O1
O2P
O
MET B:49 B:49 76.0 0.411 T -126.9 26.4 51.0 0.276 0.135 A:P21549:0.135
 PLP
GOL
SO4
BTB
HOH
 8.532
6.480
8.275
9.693
2.760
 SD
O
O
CE
O
 O1P
C3
O2
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 MET A:49 A:49 72.0 0.389 T -124.7 19.0