Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808596 . G A CCDS2543.1:NM_000030.2:c.175Gag>Aag_NP_000021.1:p.59E>K Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 GLU A:59 A:59 60.0 0.316 H -59.6 -39.7 22.0 0.116 0.2 A:P21549:0.2
 GOL
HOH
 4.243
2.548
 OE2
OE2
 O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 GLU A:59 A:59 71.0 0.374 H -69.3 -37.6 30.0 0.158 0.216 A:P21549:0.216
 HOH
 4.006
 OE2
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 GLU A:59 A:59 65.0 0.342 H -64.4 -41.3 18.0 0.095 0.247 A:P21549:0.247
 HOH
 5.147
 OE2
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 GLU A:59 A:59 60.0 NA H -47.4 -56.8 27.0 NA NA A:P21549:NA
 HOH
 6.313
 CG
 O
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 GLU A:61 A:59 65.0 0.342 H -69.5 -36.0 27.0 0.142 0.2 C:P21549:0.2
 HOH
 3.599
 N
 O
GLU C:61 C:59 85.0 0.447 H -61.5 -43.7 47.0 0.247 0.2 A:P21549:0.2
 HOH
 2.683
 OE2
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 GLU A:59 A:59 73.0 0.384 H -67.1 -37.0 34.0 0.179 0.205 A:P21549:0.205
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 GLU A:61 A:59 64.0 0.337 H -65.0 -46.3 26.0 0.137 0.2 B:P21549:0.2
 BME
HOH
 3.724
2.593
 OE2
OE2
 C2
O
GLU B:61 C:59 65.0 0.342 H -69.3 -41.2 30.0 0.158 0.184 A:P21549:0.184
 BME
HOH
 3.409
2.778
 OE2
OE2
 C2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 GLU A:61 A:59 64.0 0.337 H -63.5 -49.7 27.0 0.142 0.195 B:P21549:0.195
GLU B:61 B:59 62.0 0.326 H -63.2 -50.7 25.0 0.132 0.194 A:P21549:0.195
GLU C:61 C:59 62.0 0.326 H -62.6 -49.8 NA NA NA
GLU D:61 D:59 88.0 0.463 H -63.5 -49.3 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 GLU A:59 A:59 79.0 0.416 H -70.4 -38.6 79.0 0.416 0.0 HOH
 4.959
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 GLU A:70 A:59 84.0 0.442 H -59.9 -44.8 45.0 0.237 0.205 B:P21549:0.205
 HOH
 2.770
 OE2
 O
GLU B:70 B:59 59.0 0.311 H -66.6 -39.5 22.0 0.116 0.195 A:P21549:0.195
 HOH
 2.723
 OE2
 O
GLU C:70 E:59 84.0 0.442 H -63.6 -41.8 NA NA NA
GLU D:70 G:59 55.0 0.289 H -66.8 -38.3 NA NA NA
GLU E:70 M:59 61.0 0.321 H -67.8 -39.1 NA NA NA
GLU F:70 N:59 77.0 0.405 H -65.2 -41.8 NA NA NA
GLU G:70 S:59 59.0 0.311 H -66.1 -36.9 NA NA NA
GLU H:70 T:59 77.0 0.405 H -63.2 -43.2 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 GLU A:61 A:59 58.0 0.305 H -71.5 -42.5 23.0 0.121 0.184 B:P21549:0.184
 HOH
 4.213
 OE2
 O
GLU B:61 C:59 54.0 0.284 H -65.8 -41.6 20.0 0.105 0.179 A:P21549:0.179
 HOH
 6.414
 CG
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 GLU A:59 A:59 65.0 0.342 H -67.3 -38.4 23.0 0.121 0.221 A:P21549:0.221
 HOH
 2.697
 OE2
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 GLU A:59 A:59 62.0 0.326 H -70.7 -36.6 21.0 0.111 0.215 A:P21549:0.216
 HOH
 3.192
 OE2
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 GLU A:54 A:59 60.0 0.316 H -68.7 -39.0 21.0 0.111 0.205 B:P21549:0.205
 HOH
 2.714
 OE2
 O
GLU B:54 B:59 60.0 0.316 H -71.1 -38.0 25.0 0.132 0.184 A:P21549:0.184
 HOH
 2.741
 HG2
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 GLU A:54 A:59 58.0 0.305 H -71.0 -34.6 19.0 0.1 0.205 B:P21549:0.205
 HOH
 2.699
 OE2
 O
GLU B:54 B:59 61.0 0.321 H -69.5 -37.1 25.0 0.132 0.189 A:P21549:0.189
 HOH
 2.742
 HG2
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 GLU A:59 A:59 58.0 0.305 H -71.0 -39.4 25.0 0.132 0.173 B:P21549:0.174
 HOH
 2.595
 OE2
 O
GLU B:59 B:59 57.0 0.3 H -61.0 -45.1 14.0 0.074 0.226 A:P21549:0.226
 SO4
HOH
 9.543
2.533
 N
OE2
 O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 GLU A:59 A:59 59.0 0.311 H -60.5 -39.3