Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808663 . C A CCDS2543.1:NM_000030.2:c.242tCg>tAg_NP_000021.1:p.81S>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 SER A:81 A:81 49.0 0.426 -82.3 -174.8 2.0 0.017 0.409 A:P21549:0.409
 PLP
AOA
HOH
 2.647
9.169
3.106
 OG
OG
CA
 O3P
C1
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 SER A:81 A:81 54.0 0.47 -80.3 178.9 2.0 0.017 0.453 A:P21549:0.452
 PLP
HOH
 2.493
3.074
 OG
CA
 O1P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 SER A:81 A:81 52.0 0.452 -80.6 -177.5 1.0 0.009 0.443 A:P21549:0.443
 PMP
HOH
 2.457
3.186
 OG
CA
 O3P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 SER A:81 A:81 52.0 0.452 -88.0 -175.2 1.0 0.009 0.443 A:P21549:0.443
 PLP
 2.415
 OG
 O1P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 SER A:83 A:81 45.0 0.391 -60.3 171.0 0.0 0.0 0.391 C:P21549:0.391
 HOH
 3.063
 CB
 O
SER C:83 C:81 44.0 0.383 -71.3 170.6 0.0 0.0 0.383 A:P21549:0.383
 HOH
 2.729
 CB
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 SER A:81 A:81 50.0 0.435 -71.3 -175.3 2.0 0.017 0.418 A:P21549:0.417
 PLP
DIO
HOH
 2.470
8.867
3.143
 OG
OG
CA
 O2P
C2
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 SER A:83 A:81 70.0 0.609 -61.9 174.2 4.0 0.035 0.574 B:P21549:0.574
 SO4
BME
HOH
 2.443
6.394
3.305
 OG
OG
CA
 O2
S2
O
SER B:83 C:81 70.0 0.609 -70.2 171.8 2.0 0.017 0.592 A:P21549:0.591
 SO4
BME
BME
HOH
 3.159
7.475
8.616
3.303
 CB
OG
N
OG
 O4
O1
C2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 SER A:83 A:81 38.0 0.33 -91.5 -171.7 1.0 0.009 0.321 B:P21549:0.322
 GOL
 9.801
 CB
 O3
SER B:83 B:81 40.0 0.348 -89.1 -173.1 0.0 0.0 0.348 A:P21549:0.348
SER C:83 C:81 41.0 0.357 -86.6 -172.6 NA NA NA
SER D:83 D:81 39.0 0.339 -88.9 -174.0 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 SER A:81 A:81 39.0 0.339 -72.3 179.9 39.0 0.339 0.0 AOA
HOH
 9.918
3.093
 OG
CA
 C1
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 SER A:92 A:81 52.0 0.452 -81.2 -175.3 2.0 0.017 0.435 B:P21549:0.435
 PLP
HOH
 2.711
3.483
 OG
CA
 O2P
O
SER B:92 B:81 52.0 0.452 -77.5 -174.3 2.0 0.017 0.435 A:P21549:0.435
 PLP
HOH
 2.917
3.092
 OG
CB
 O3P
O
SER C:92 E:81 51.0 0.443 -77.1 -176.3 NA NA NA
SER D:92 G:81 52.0 0.452 -78.8 -177.7 NA NA NA
SER E:92 M:81 51.0 0.443 -74.5 -173.9 NA NA NA
SER F:92 N:81 53.0 0.461 -78.1 -172.2 NA NA NA
SER G:92 S:81 51.0 0.443 -74.9 -174.9 NA NA NA
SER H:92 T:81 52.0 0.452 -78.0 -171.4 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 SER A:83 A:81 74.0 0.643 -55.1 174.8 4.0 0.035 0.608 B:P21549:0.609
 SO4
BME
 2.973
9.028
 OG
OG
 O1
S2
SER B:83 C:81 75.0 0.652 -59.4 176.5 6.0 0.052 0.6 A:P21549:0.6
 SO4
HOH
 2.790
9.675
 OG
C
 O2
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 SER A:81 A:81 52.0 0.452 -60.8 -177.7 2.0 0.017 0.435 A:P21549:0.435
 PLP
GOL
HOH
 2.610
8.792
2.923
 OG
CB
CA
 O1P
O1
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 SER A:81 A:81 50.0 0.435 -68.8 176.2 2.0 0.017 0.418 A:P21549:0.417
 PLP
HOH
 2.259
3.122
 OG
CA
 O3P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 SER A:76 A:81 51.0 0.443 -72.5 -179.0 2.0 0.017 0.426 B:P21549:0.426
 PLP
HOH
 1.940
2.418
 HG
HA
 O2P
O
SER B:76 B:81 50.0 0.435 -71.3 -175.6 1.0 0.009 0.426 A:P21549:0.426
 PLP
HOH
 1.890
2.378
 HG
HA
 O3P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 SER A:76 A:81 51.0 0.443 -73.6 -179.1 2.0 0.017 0.426 B:P21549:0.426
 PLR
HOH
 1.838
2.432
 HG
HA
 O2P
O
SER B:76 B:81 50.0 0.435 -72.7 -177.1 1.0 0.009 0.426 A:P21549:0.426
 PLR
HOH
 1.928
2.320
 HG
HA
 O2P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 SER A:81 A:81 52.0 0.452 -71.1 -174.7 2.0 0.017 0.435 B:P21549:0.435
 PLP
HOH
 2.887
3.318
 OG
CA
 O2P
O
SER B:81 B:81 50.0 0.435 -70.5 -176.3 2.0 0.017 0.418 A:P21549:0.417
 PLP
HOH
 2.723
3.317
 OG
CA
 O3P
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 SER A:81 A:81 50.0 0.435 -66.5 176.9