Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808669 . A C CCDS2543.1:NM_000030.2:c.248cAc>cCc_NP_000021.1:p.83H>P Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 HIS A:83 A:83 63.0 0.323 H -49.1 -48.4 8.0 0.041 0.282 A:P21549:0.282
 PLP
AOA
GOL
HOH
 2.511
6.930
6.968
2.763
 ND1
CE1
NE2
CB
 O3P
C1
O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 HIS A:83 A:83 63.0 0.323 H -49.5 -35.4 7.0 0.036 0.287 A:P21549:0.287
 PLP
HOH
 2.580
6.212
 N
N
 O1P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:83 A:83 69.0 0.354 H -40.3 -39.7 7.0 0.036 0.318 A:P21549:0.318
 PMP
HOH
 2.618
6.554
 N
N
 O3P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:83 A:83 69.0 0.354 H -50.2 -36.3 9.0 0.046 0.308 A:P21549:0.308
 PLP
 2.892
 N
 O1P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 HIS A:85 A:83 19.0 NA H -93.9 -1.0 8.0 NA NA C:P21549:NA
 HOH
 2.679
 O
 O
HIS C:85 C:83 33.0 NA H -69.0 -24.9 12.0 NA NA A:P21549:NA
 HOH
 2.914
 CB
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 HIS A:83 A:83 68.0 0.349 H -56.6 -29.0 10.0 0.051 0.298 A:P21549:0.297
 PLP
DIO
HOH
 2.870
7.490
6.542
 N
CE1
N
 O2P
C2
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 HIS A:85 A:83 36.0 0.185 T -92.3 9.8 24.0 0.123 0.062 B:P21549:0.062
 SO4
BME
HOH
 2.708
8.901
2.808
 ND1
C
O
 O3
S2
O
HIS B:85 C:83 41.0 0.21 T -90.2 5.7 31.0 0.159 0.051 A:P21549:0.051
 SO4
HOH
 2.769
2.863
 ND1
O
 O3
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 HIS A:85 A:83 51.0 0.262 H -60.8 -37.7 4.0 0.021 0.241 B:P21549:0.241
 GOL
GOL
 7.336
8.083
 CE1
NE2
 C1
O1
HIS B:85 B:83 48.0 0.246 H -63.9 -36.0 3.0 0.015 0.231 A:P21549:0.231
 GOL
 7.945
 CE1
 C2
HIS C:85 C:83 49.0 0.251 H -62.9 -36.1 NA NA NA
HIS D:85 D:83 51.0 0.262 H -62.9 -36.5 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 HIS A:83 A:83 52.0 0.267 H -54.7 -47.1 52.0 0.267 0.0 AOA
GOL
HOH
 8.015
7.203
6.355
 CE1
NE2
N
 O2
O2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 HIS A:94 A:83 67.0 0.344 H -57.9 -37.7 9.0 0.046 0.298 B:P21549:0.297
 PLP
HOH
 2.842
2.975
 ND1
O
 O2P
O
HIS B:94 B:83 67.0 0.344 H -56.9 -38.1 9.0 0.046 0.298 A:P21549:0.297
 PLP
HOH
 2.813
3.054
 N
O
 O3P
O
HIS C:94 E:83 67.0 0.344 H -53.8 -42.8 NA NA NA
HIS D:94 G:83 66.0 0.338 H -58.7 -35.7 NA NA NA
HIS E:94 M:83 67.0 0.344 H -60.6 -40.7 NA NA NA
HIS F:94 N:83 68.0 0.349 H -61.2 -37.0 NA NA NA
HIS G:94 S:83 67.0 0.344 H -60.9 -39.5 NA NA NA
HIS H:94 T:83 68.0 0.349 H -62.0 -36.5 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 HIS A:85 A:83 35.0 0.179 T -103.4 16.9 24.0 0.123 0.056 B:P21549:0.056
 SO4
BME
HOH
 2.748
6.056
6.143
 N
CE1
NE2
 O3
C1
O
HIS B:85 C:83 35.0 0.179 T -98.2 23.9 23.0 0.118 0.061 A:P21549:0.062
 SO4
HOH
 2.454
2.944
 ND1
NE2
 O3
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 HIS A:83 A:83 61.0 0.313 H -47.3 -38.5 5.0 0.026 0.287 A:P21549:0.287
 PLP
GOL
HOH
 2.635
6.831
2.824
 N
CE1
O
 O1P
C1
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 HIS A:83 A:83 70.0 0.359 H -31.4 -44.4 11.0 0.056 0.303 A:P21549:0.303
 PLP
HOH
 2.965
6.443
 N
N
 O3P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 HIS A:78 A:83 69.0 0.354 H -52.5 -38.3 8.0 0.041 0.313 B:P21549:0.313
 PLP
HOH
 2.011
2.602
 HD1
HB3
 O2P
O
HIS B:78 B:83 68.0 0.349 H -54.9 -38.9 8.0 0.041 0.308 A:P21549:0.308
 PLP
HOH
 2.052
2.610
 H
HB3
 O3P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 HIS A:78 A:83 67.0 0.344 H -52.1 -39.2 8.0 0.041 0.303 B:P21549:0.303
 PLR
HOH
 2.039
2.633
 HD1
HB3
 O2P
O
HIS B:78 B:83 69.0 0.354 H -57.0 -38.0 8.0 0.041 0.313 A:P21549:0.313
 PLR
HOH
 1.978
2.531
 H
HB3
 O2P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 HIS A:83 A:83 67.0 0.344 H -53.8 -36.7 8.0 0.041 0.303 B:P21549:0.303
 PLP
HOH
 2.828
3.019
 N
O
 O2P
O
HIS B:83 B:83 66.0 0.338 H -55.8 -37.3 8.0 0.041 0.297 A:P21549:0.297
 PLP
HOH
 2.826
2.939
 ND1
O
 O3P
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 HIS A:83 A:83 64.0 0.328 H -64.9 -32.3