Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808673 . T A CCDS2543.1:NM_000030.2:c.252tgT>tgA_NP_000021.1:p.84C>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 CYS A:84 A:84 27.0 0.2 H -57.8 -28.8 1.0 0.007 0.193 A:P21549:0.193
 PLP
HOH
 5.034
3.905
 N
N
 O3P
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 CYS A:84 A:84 25.0 0.185 H -72.0 -35.5 0.0 0.0 0.185 A:P21549:0.185
 PLP
HOH
 4.806
6.722
 N
SG
 O1P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:84 A:84 29.0 0.215 H -68.4 -35.1 0.0 0.0 0.215 A:P21549:0.215
 PMP
HOH
 4.790
7.543
 N
N
 O3P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:84 A:84 28.0 0.207 H -68.2 -45.9 0.0 0.0 0.207 A:P21549:0.207
 PLP
 4.986
 N
 O1P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 CYS A:86 A:84 26.0 0.193 H -76.7 -33.1 0.0 0.0 0.193 C:P21549:0.193
 HOH
 4.263
 N
 O
CYS C:86 C:84 27.0 0.2 H -68.4 -47.5 0.0 0.0 0.2 A:P21549:0.2
 HOH
 6.103
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 CYS A:84 A:84 27.0 0.2 H -71.5 -46.4 1.0 0.007 0.193 A:P21549:0.193
 PLP
HOH
 4.959
7.360
 N
CB
 O2P
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 CYS A:86 A:84 29.0 0.215 H -68.4 -34.7 0.0 0.0 0.215 B:P21549:0.215
 SO4
BME
HOH
 5.251
7.276
4.070
 N
CB
N
 O3
S2
O
CYS B:86 C:84 33.0 0.244 H -63.8 -36.1 1.0 0.007 0.237 A:P21549:0.237
 SO4
BME
HOH
 5.232
6.574
3.986
 N
SG
N
 O3
C2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 CYS A:86 A:84 26.0 0.193 H -70.1 -40.9 0.0 0.0 0.193 B:P21549:0.193
CYS B:86 B:84 26.0 0.193 H -70.6 -41.2 0.0 0.0 0.193 A:P21549:0.193
CYS C:86 C:84 27.0 0.2 H -71.4 -41.6 NA NA NA
CYS D:86 D:84 25.0 0.185 H -71.2 -40.8 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 CYS A:84 A:84 25.0 0.185 H -58.7 -32.4 25.0 0.185 0.0 HOH
 6.078
 SG
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 CYS A:95 A:84 27.0 0.2 H -68.1 -36.9 0.0 0.0 0.2 B:P21549:0.2
 PLP
HOH
 4.980
3.791
 N
SG
 O2P
O
CYS B:95 B:84 26.0 0.193 H -68.6 -37.0 0.0 0.0 0.193 A:P21549:0.193
 PLP
HOH
 4.987
3.534
 N
SG
 O3P
O
CYS C:95 E:84 25.0 0.185 H -62.4 -42.7 NA NA NA
CYS D:95 G:84 26.0 0.193 H -67.1 -39.7 NA NA NA
CYS E:95 M:84 25.0 0.185 H -63.9 -43.0 NA NA NA
CYS F:95 N:84 25.0 0.185 H -65.8 -41.8 NA NA NA
CYS G:95 S:84 26.0 0.193 H -60.1 -44.7 NA NA NA
CYS H:95 T:84 27.0 0.2 H -65.9 -41.7 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 CYS A:86 A:84 30.0 0.222 H -68.7 -28.6 0.0 0.0 0.222 B:P21549:0.222
 SO4
 4.602
 N
 O3
CYS B:86 C:84 29.0 0.215 H -77.6 -30.5 0.0 0.0 0.215 A:P21549:0.215
 SO4
HOH
 5.118
9.648
 N
N
 O2
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 CYS A:84 A:84 26.0 0.193 H -74.0 -30.7 0.0 0.0 0.193 A:P21549:0.193
 PLP
HOH
 4.801
4.083
 N
N
 O1P
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 CYS A:84 A:84 27.0 0.2 H -67.8 -36.1 0.0 0.0 0.2 A:P21549:0.2
 PLP
HOH
 4.772
6.376
 N
SG
 O3P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 CYS A:79 A:84 25.0 0.185 H -69.9 -36.9 0.0 0.0 0.185 B:P21549:0.185
 PLP
HOH
 4.531
4.223
 H
HA
 O2P
O
CYS B:79 B:84 24.0 0.178 H -67.4 -37.1 0.0 0.0 0.178 A:P21549:0.178
 PLP
HOH
 4.457
4.174
 H
HA
 O3P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 CYS A:79 A:84 25.0 0.185 H -68.8 -35.4 0.0 0.0 0.185 B:P21549:0.185
 PLR
HOH
 4.513
4.174
 H
HA
 O2P
O
CYS B:79 B:84 25.0 0.185 H -68.4 -33.9 0.0 0.0 0.185 A:P21549:0.185
 PLR
HOH
 4.401
4.207
 H
HA
 O2P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 CYS A:84 A:84 26.0 0.193 H -70.1 -35.5 0.0 0.0 0.193 B:P21549:0.193
 PLP
HOH
 5.031
4.403
 N
N
 O2P
O
CYS B:84 B:84 25.0 0.185 H -69.3 -35.9 0.0 0.0 0.185 A:P21549:0.185
 PLP
HOH
 5.028
4.231
 N
N
 O3P
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 CYS A:84 A:84 27.0 0.2 H -68.3 -36.4