Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808744 . G A CCDS2543.1:NM_000030.2:c.323tGg>tAg_NP_000021.1:p.108W>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 TRP A:108 A:108 37.0 0.145 H -66.8 -38.9 22.0 0.086 0.059 A:P21549:0.059
 PLP
AOA
GOL
HOH
 3.336
4.229
5.744
6.546
 CH2
CZ2
N
CD1
 C5
O2
O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 TRP A:108 A:108 38.0 0.149 H -67.7 -36.4 18.0 0.071 0.078 A:P21549:0.078
 PLP
HOH
 3.161
4.713
 CH2
CZ2
 C5
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:108 A:108 48.0 0.188 H -61.1 -45.2 30.0 0.118 0.07 A:P21549:0.071
 PMP
HOH
 2.993
6.271
 CD2
CD1
 N1
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:108 A:108 70.0 0.275 360.0 -52.4 50.0 0.196 0.079 A:P21549:0.078
 PLP
 3.103
 NE1
 C2A
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 TRP A:110 A:108 11.0 0.043 H -67.4 -42.9 1.0 0.004 0.039 C:P21549:0.039
 HOH
 3.852
 CZ3
 O
TRP C:110 C:108 14.0 0.055 H -76.1 -40.7 5.0 0.02 0.035 A:P21549:0.035
 HOH
 3.529
 CZ2
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 TRP A:108 A:108 46.0 0.18 H -75.0 -26.2 29.0 0.114 0.066 A:P21549:0.067
 PLP
DIO
HOH
 3.226
4.207
3.830
 CZ3
CZ2
CB
 C6
O1'
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 TRP A:110 A:108 25.0 0.098 H -65.7 -44.5 6.0 0.024 0.074 B:P21549:0.075
 SO4
HOH
 4.636
3.207
 CH2
NE1
 O3
O
TRP B:110 C:108 26.0 0.102 H -70.0 -43.3 7.0 0.027 0.075 A:P21549:0.075
 SO4
BME
HOH
 4.607
9.006
3.280
 CZ3
CZ2
NE1
 O3
O1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 TRP A:110 A:108 13.0 0.051 H -59.3 -39.3 5.0 0.02 0.031 B:P21549:0.031
 GOL
GOL
 4.367
7.611
 CH2
N
 C1
C2
TRP B:110 B:108 13.0 0.051 H -59.1 -39.7 5.0 0.02 0.031 A:P21549:0.031
 GOL
 5.027
 CH2
 C2
TRP C:110 C:108 12.0 0.047 H -59.8 -39.5 NA NA NA
TRP D:110 D:108 12.0 0.047 H -60.7 -38.5 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 TRP A:108 A:108 15.0 0.059 H -64.4 -49.7 15.0 0.059 0.0 AOA
GOL
HOH
 4.109
5.880
6.324
 CZ2
N
CD1
 O2
O3
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 TRP A:119 A:108 43.0 0.169 H -71.1 -43.4 25.0 0.098 0.071 B:P21549:0.071
 PLP
HOH
 3.291
3.074
 CZ3
O
 C6
O
TRP B:119 B:108 47.0 0.184 H -71.0 -40.0 29.0 0.114 0.07 A:P21549:0.071
 PLP
HOH
 3.325
3.118
 CD2
O
 N1
O
TRP C:119 E:108 44.0 0.173 H -71.2 -40.9 NA NA NA
TRP D:119 G:108 45.0 0.176 H -69.1 -44.0 NA NA NA
TRP E:119 M:108 43.0 0.169 H -66.9 -43.0 NA NA NA
TRP F:119 N:108 43.0 0.169 H -75.5 -40.2 NA NA NA
TRP G:119 S:108 46.0 0.18 H -72.8 -46.2 NA NA NA
TRP H:119 T:108 47.0 0.184 H -67.9 -42.5 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 TRP A:110 A:108 21.0 0.082 H -77.4 -33.6 3.0 0.012 0.07 B:P21549:0.071
 SO4
BME
HOH
 5.120
3.865
3.683
 CH2
CZ2
N
 O4
C1
O
TRP B:110 C:108 22.0 0.086 H -72.3 -32.4 4.0 0.016 0.07 A:P21549:0.071
 SO4
HOH
 4.767
3.361
 CH2
NE1
 O4
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 TRP A:108 A:108 43.0 0.169 H -67.9 -44.6 26.0 0.102 0.067 A:P21549:0.067
 PLP
GOL
HOH
 3.238
4.261
2.982
 NE1
CZ2
CB
 C2A
O2
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 TRP A:108 A:108 35.0 0.137 H -68.0 -43.0 21.0 0.082 0.055 A:P21549:0.055
 PLP
HOH
 3.217
3.416
 NE1
CB
 C2A
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 TRP A:103 A:108 36.0 0.141 H -69.1 -41.6 20.0 0.078 0.063 B:P21549:0.063
 PLP
HOH
 2.630
2.923
 HH2
HZ2
 H5A1
O
TRP B:103 B:108 36.0 0.141 H -74.9 -47.9 19.0 0.075 0.066 A:P21549:0.067
 PLP
HOH
 2.543
2.758
 HH2
HB2
 H5A1
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 TRP A:103 A:108 40.0 0.157 H -69.8 -41.8 23.0 0.09 0.067 B:P21549:0.067
 PLR
HOH
 2.733
2.908
 HH2
HB2
 H5A1
O
TRP B:103 B:108 41.0 0.161 H -73.5 -47.0 23.0 0.09 0.071 A:P21549:0.071
 PLR
HOH
 2.462
2.800
 HH2
HB2
 H5A1
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 TRP A:108 A:108 35.0 0.137 H -71.8 -42.4 20.0 0.078 0.059 B:P21549:0.059
 PLP
HOH
 3.286
3.761
 CH2
N
 C5
O
TRP B:108 B:108 38.0 0.149 H -67.5 -40.4 22.0 0.086 0.063 A:P21549:0.063
 PLP
HOH
 3.251
3.771
 CD2
CZ2
 N1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 TRP A:108 A:108 43.0 0.169 H -71.5 -38.2