Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241808752 . C A CCDS2543.1:NM_000030.2:c.331Cga>Aga_NP_000021.1:p.111R>R Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ARG A:111 A:111 96.0 0.427 H -64.0 -36.6 15.0 0.067 0.36 A:P21549:0.36
 PLP
AOA
GOL
HOH
 6.852
8.247
2.843
4.790
 NH1
NH1
NE
NH2
 O3P
C1
O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ARG A:111 A:111 98.0 0.436 H -65.8 -38.5 14.0 0.062 0.374 A:P21549:0.373
 PLP
HOH
 7.423
4.355
 NH1
N
 C5A
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:111 A:111 99.0 0.44 H -67.7 -53.9 22.0 0.098 0.342 A:P21549:0.342
 PMP
HOH
 6.790
9.908
 NH1
N
 O1P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:111 A:111 131.0 0.582 H -77.0 -53.4 48.0 0.213 0.369 A:P21549:0.369
 PLP
 6.706
 NH1
 O3P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ARG A:113 A:111 118.0 0.524 H -60.8 -42.2 19.0 0.084 0.44 C:P21549:0.44
 BTB
HOH
 7.141
2.915
 NH2
NH2
 O8
O
ARG C:113 C:111 120.0 0.533 H -59.2 -45.8 17.0 0.076 0.457 A:P21549:0.458
 HOH
 2.751
 NE
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ARG A:111 A:111 101.0 0.449 H -65.9 -46.1 20.0 0.089 0.36 A:P21549:0.36
 PLP
DIO
HOH
 6.728
8.594
7.300
 NH1
NH1
NH2
 O1P
O1'
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ARG A:113 A:111 122.0 0.542 H -57.4 -42.2 17.0 0.076 0.466 B:P21549:0.467
 SO4
BTB
HOH
 5.807
6.965
4.156
 NH1
NH2
NE
 O3
O6
O
ARG B:113 C:111 125.0 0.556 H -66.7 -38.7 21.0 0.093 0.463 A:P21549:0.462
 SO4
BTB
BME
HOH
 6.041
7.872
9.518
2.817
 NH1
NH2
NH2
NH1
 O3
C7
O1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ARG A:113 A:111 99.0 0.44 H -63.5 -47.4 21.0 0.093 0.347 B:P21549:0.347
 GOL
GOL
 7.998
3.543
 NH1
NH2
 C1
O3
ARG B:113 B:111 101.0 0.449 H -62.3 -46.9 19.0 0.084 0.365 A:P21549:0.364
 GOL
 8.664
 NH1
 C2
ARG C:113 C:111 102.0 0.453 H -63.1 -45.6 NA NA NA
ARG D:113 D:111 99.0 0.44 H -62.1 -46.4 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ARG A:111 A:111 99.0 0.44 H -67.8 -40.3 99.0 0.44 0.0 AOA
GOL
HOH
 9.036
3.092
6.341
 NH1
NE
N
 O1
O2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ARG A:122 A:111 104.0 0.462 H -60.1 -40.4 18.0 0.08 0.382 B:P21549:0.382
 PLP
BTB
HOH
 7.089
7.271
2.957
 NH1
NH2
NE
 O2P
C7
O
ARG B:122 B:111 104.0 0.462 H -63.9 -38.9 20.0 0.089 0.373 A:P21549:0.373
 BTB
PLP
HOH
 7.414
6.984
3.039
 NH2
NH1
NE
 C7
O3P
O
ARG C:122 E:111 106.0 0.471 H -67.7 -38.0 NA NA NA
ARG D:122 G:111 103.0 0.458 H -68.7 -35.9 NA NA NA
ARG E:122 M:111 104.0 0.462 H -66.3 -41.4 NA NA NA
ARG F:122 N:111 100.0 0.444 H -62.8 -39.9 NA NA NA
ARG G:122 S:111 105.0 0.467 H -63.9 -40.5 NA NA NA
ARG H:122 T:111 104.0 0.462 H -63.5 -43.2 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ARG A:113 A:111 124.0 0.551 H -63.4 -45.4 21.0 0.093 0.458 B:P21549:0.458
 SO4
BME
HOH
 6.332
8.211
6.826
 NH1
NH1
N
 O2
C2
O
ARG B:113 C:111 125.0 0.556 H -59.9 -44.6 21.0 0.093 0.463 A:P21549:0.462
 SO4
HOH
 6.357
7.202
 NH1
N
 O2
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ARG A:111 A:111 95.0 0.422 H -58.0 -39.1 15.0 0.067 0.355 A:P21549:0.356
 PLP
GOL
HOH
 7.149
7.998
2.430
 NH1
NH2
NH2
 O1P
C3
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ARG A:111 A:111 93.0 0.413 H -66.0 -40.0 15.0 0.067 0.346 A:P21549:0.347
 PLP
HOH
 7.064
6.880
 NH1
N
 O4P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ARG A:106 A:111 97.0 0.431 H -67.0 -38.4 17.0 0.076 0.355 B:P21549:0.356
 PLP
HOH
 5.887
2.024
 HG3
HE
 H6
O
ARG B:106 B:111 100.0 0.444 H -66.9 -37.0 19.0 0.084 0.36 A:P21549:0.36
 PLP
HOH
 5.886
1.799
 HG3
HE
 H5A2
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ARG A:106 A:111 98.0 0.436 H -68.5 -38.9 18.0 0.08 0.356 B:P21549:0.356
 PLR
HOH
 5.787
1.974
 HG3
HE
 H5A1
O
ARG B:106 B:111 98.0 0.436 H -67.6 -37.1 19.0 0.084 0.352 A:P21549:0.351
 PLR
HOH
 5.710
1.772
 HG3
HE
 H5A2
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ARG A:111 A:111 97.0 0.431 H -64.8 -36.7 13.0 0.058 0.373 B:P21549:0.373
 PLP
BTB
GOL
HOH
 6.850
7.380
8.437
2.972
 NH1
NH2
NE
NH2
 O2P
O1
O3
O
ARG B:111 B:111 101.0 0.449 H -70.0 -37.5 14.0 0.062 0.387 A:P21549:0.387
 BTB
PLP
HOH
 7.052
6.976
2.864
 NH2
NH1
NE
 O1
O3P
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ARG A:111 A:111 103.0 0.458 H -68.0 -39.2