Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241810073 . A C CCDS2543.1:NM_000030.2:c.371cAc>cCc_NP_000021.1:p.124H>P Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 HIS A:124 A:124 56.0 0.287 B -120.3 96.4 56.0 0.287 0.0 HOH
 3.456
 ND1
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 HIS A:124 A:124 54.0 0.277 E -110.5 102.7 54.0 0.277 0.0
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:124 A:124 49.0 0.251 E -105.0 86.2 49.0 0.251 0.0 HOH
 9.111
 O
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:124 A:124 54.0 0.277 E -117.2 90.0 54.0 0.277 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 HIS A:126 A:124 47.0 0.241 E -120.6 102.1 47.0 0.241 0.0 HOH
 2.618
 NE2
 O
HIS C:126 C:124 49.0 0.251 E -119.8 96.5 49.0 0.251 0.0 HOH
 2.894
 ND1
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 HIS A:124 A:124 19.0 NA E -113.3 95.2 19.0 NA NA HOH
 2.752
 O
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 HIS A:126 A:124 52.0 0.267 E -127.6 94.6 52.0 0.267 0.0 BME
HOH
 6.738
2.599
 C
NE2
 C1
O
HIS B:126 C:124 50.0 0.256 E -120.8 91.0 50.0 0.256 0.0 HOH
 2.909
 NE2
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 HIS A:126 A:124 49.0 0.251 E -133.8 96.1 49.0 0.251 0.0
HIS B:126 B:124 43.0 0.221 E -134.6 94.4 43.0 0.221 0.0
HIS C:126 C:124 45.0 0.231 E -135.3 96.1 NA NA NA
HIS D:126 D:124 47.0 0.241 E -134.6 94.8 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 HIS A:124 A:124 46.0 0.236 E -118.5 102.5 46.0 0.236 0.0 HOH
 2.905
 ND1
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 HIS A:135 A:124 47.0 0.241 E -129.9 98.1 47.0 0.241 0.0 HOH
 2.873
 ND1
 O
HIS B:135 B:124 48.0 0.246 E -125.7 95.8 48.0 0.246 0.0 HOH
 2.801
 NE2
 O
HIS C:135 E:124 43.0 0.221 E -126.3 97.0 NA NA NA
HIS D:135 G:124 41.0 0.21 E -128.5 95.1 NA NA NA
HIS E:135 M:124 48.0 0.246 E -126.5 96.9 NA NA NA
HIS F:135 N:124 47.0 0.241 E -124.7 96.8 NA NA NA
HIS G:135 S:124 47.0 0.241 E -125.4 94.4 NA NA NA
HIS H:135 T:124 48.0 0.246 E -132.7 95.7 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 HIS A:126 A:124 48.0 0.246 E -112.5 101.3 48.0 0.246 0.0
HIS B:126 C:124 54.0 0.277 E -113.4 97.6 54.0 0.277 0.0 HOH
 7.942
 NE2
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 HIS A:124 A:124 51.0 0.262 E -123.6 94.4 51.0 0.262 0.0
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 HIS A:124 A:124 37.0 0.19 E -115.0 103.6 37.0 0.19 0.0
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 HIS A:119 A:124 47.0 0.241 E -120.8 94.0 47.0 0.241 0.0 HOH
 1.806
 HD1
 O
HIS B:119 B:124 33.0 0.169 E -125.6 93.4 33.0 0.169 0.0 HOH
 2.727
 HB3
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 HIS A:119 A:124 48.0 0.246 E -126.0 95.2 48.0 0.246 0.0 HOH
 1.834
 HD1
 O
HIS B:119 B:124 35.0 0.179 E -125.3 92.2 35.0 0.179 0.0 HOH
 2.479
 HB3
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 HIS A:124 A:124 38.0 0.195 E -125.1 96.7 38.0 0.195 0.0 HOH
 2.765
 NE2
 O
HIS B:124 B:124 34.0 0.174 E -120.6 94.5 34.0 0.174 0.0 HOH
 2.809
 NE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 HIS A:124 A:124 39.0 0.2 E -127.6 91.7