Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241810799 . T A CCDS2543.1:NM_000030.2:c.457Tta>Ata_NP_000021.1:p.153L>I Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 LEU A:153 A:153 1.0 0.006 E -131.2 134.1 1.0 0.006 0.0 PLP
HOH
 7.955
3.726
 O
CD2
 C2A
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 LEU A:153 A:153 2.0 0.012 E -132.1 129.7 2.0 0.012 0.0 PLP
HOH
 8.240
7.300
 O
O
 C2A
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 LEU A:153 A:153 12.0 NA E -129.2 123.5 12.0 NA NA PMP
HOH
 8.524
2.714
 O
CA
 C2A
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 LEU A:153 A:153 21.0 NA E -120.0 130.6 21.0 NA NA PLP
 8.319
 O
 C2A
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 LEU A:155 A:153 1.0 0.006 E -131.0 132.9 1.0 0.006 0.0 HOH
 3.597
 CA
 O
LEU C:155 C:153 1.0 0.006 E -130.0 134.2 1.0 0.006 0.0 HOH
 3.734
 CA
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 LEU A:153 A:153 6.0 0.035 E -125.3 132.6 6.0 0.035 0.0 PLP
HOH
 8.051
5.938
 O
C
 C2A
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 LEU A:155 A:153 1.0 0.006 E -131.5 141.9 1.0 0.006 0.0 BME
HOH
 9.090
3.308
 CD1
CA
 C1
O
LEU B:155 C:153 1.0 0.006 E -133.4 138.0 1.0 0.006 0.0 HOH
 3.566
 CA
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 LEU A:155 A:153 0.0 0.0 E -132.6 144.2 0.0 0.0 0.0
LEU B:155 B:153 0.0 0.0 E -131.9 143.7 0.0 0.0 0.0
LEU C:155 C:153 0.0 0.0 E -131.2 143.9 NA NA NA
LEU D:155 D:153 0.0 0.0 E -131.2 143.0 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 LEU A:153 A:153 0.0 0.0 E -142.6 133.4 0.0 0.0 0.0 HOH
 3.612
 CA
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 LEU A:164 A:153 0.0 0.0 E -126.2 138.3 0.0 0.0 0.0 PLP
HOH
 8.373
3.559
 O
CA
 C2A
O
LEU B:164 B:153 1.0 0.006 E -130.4 140.1 1.0 0.006 0.0 PLP
HOH
 8.435
3.449
 O
CA
 C2A
O
LEU C:164 E:153 1.0 0.006 E -128.9 136.7 NA NA NA
LEU D:164 G:153 1.0 0.006 E -130.4 140.4 NA NA NA
LEU E:164 M:153 0.0 0.0 E -133.4 141.5 NA NA NA
LEU F:164 N:153 0.0 0.0 E -131.3 140.8 NA NA NA
LEU G:164 S:153 0.0 0.0 E -132.6 137.9 NA NA NA
LEU H:164 T:153 0.0 0.0 E -132.9 137.1 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 LEU A:155 A:153 1.0 0.006 E -139.8 137.2 1.0 0.006 0.0 HOH
 6.056
 C
 O
LEU B:155 C:153 0.0 0.0 E -132.8 142.6 0.0 0.0 0.0 HOH
 5.761
 C
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 LEU A:153 A:153 2.0 0.012 E -138.7 132.6 2.0 0.012 0.0 PLP
HOH
 8.194
5.217
 O
CD1
 C2A
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 LEU A:153 A:153 0.0 0.0 E -129.5 135.9 0.0 0.0 0.0 PLP
HOH
 8.017
3.327
 O
CA
 C2A
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 LEU A:148 A:153 0.0 0.0 E -134.4 132.2 0.0 0.0 0.0 PLP
HOH
 7.811
2.644
 O
HA
 H2A2
O
LEU B:148 B:153 0.0 0.0 E -130.9 131.1 0.0 0.0 0.0 PLP
HOH
 7.550
2.784
 O
HA
 H2A2
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 LEU A:148 A:153 0.0 0.0 E -137.8 133.9 0.0 0.0 0.0 PLR
HOH
 7.994
2.573
 O
HA
 H2A2
O
LEU B:148 B:153 1.0 0.006 E -129.2 133.2 1.0 0.006 0.0 PLR
HOH
 7.727
2.724
 O
HA
 H2A2
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 LEU A:153 A:153 0.0 0.0 E -134.3 134.3 0.0 0.0 0.0 PLP
HOH
 8.345
3.569
 O
CA
 C2A
O
LEU B:153 B:153 0.0 0.0 E -131.1 137.7 0.0 0.0 0.0 PLP
GOL
HOH
 8.317
9.852
3.470
 O
CD1
CA
 C2A
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 LEU A:153 A:153 0.0 0.0 E -128.8 142.7