Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241810839 . T A CCDS2543.1:NM_000030.2:c.497cTt>cAt_NP_000021.1:p.166L>H Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 LEU A:166 A:166 4.0 0.024 -128.6 -10.7 4.0 0.024 0.0 HOH
 4.884
 O
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 LEU A:166 A:166 9.0 0.053 -126.0 -21.5 9.0 0.053 0.0 HOH
 5.966
 CD1
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 LEU A:166 A:166 12.0 0.071 -107.6 -36.5 12.0 0.071 0.0 HOH
 8.109
 CD2
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 LEU A:166 A:166 18.0 NA -103.5 -44.2 18.0 NA NA HOH
 8.342
 N
 O
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 LEU A:168 A:166 6.0 0.035 -117.7 -18.8 6.0 0.035 0.0 HOH
 2.949
 N
 O
LEU C:168 C:166 6.0 0.035 -119.9 -20.8 6.0 0.035 0.0 HOH
 2.911
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 LEU A:166 A:166 11.0 0.065 -121.4 -32.8 11.0 0.065 0.0 HOH
 8.716
 CD1
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 LEU A:168 A:166 8.0 0.047 -116.0 -16.7 8.0 0.047 0.0 BME
HOH
 3.277
2.953
 N
N
 C1
O
LEU B:168 C:166 7.0 0.041 -113.5 -23.8 7.0 0.041 0.0 HOH
 2.656
 O
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 LEU A:168 A:166 7.0 0.041 -109.3 -19.1 7.0 0.041 0.0
LEU B:168 B:166 7.0 0.041 -107.1 -19.8 7.0 0.041 0.0
LEU C:168 C:166 7.0 0.041 -108.4 -18.5 NA NA NA
LEU D:168 D:166 8.0 0.047 -109.0 -19.2 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 LEU A:166 A:166 3.0 0.018 -110.7 -2.7 3.0 0.018 0.0 HOH
 3.488
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 LEU A:177 A:166 6.0 0.035 -118.8 -20.5 6.0 0.035 0.0 HOH
 2.708
 O
 O
LEU B:177 B:166 7.0 0.041 -115.1 -20.6 7.0 0.041 0.0 HOH
 2.551
 O
 O
LEU C:177 E:166 6.0 0.035 -119.5 -22.8 NA NA NA
LEU D:177 G:166 7.0 0.041 -115.6 -24.7 NA NA NA
LEU E:177 M:166 5.0 0.029 -115.4 -20.2 NA NA NA
LEU F:177 N:166 7.0 0.041 -113.2 -22.1 NA NA NA
LEU G:177 S:166 7.0 0.041 -111.8 -23.2 NA NA NA
LEU H:177 T:166 7.0 0.041 -113.1 -22.7 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 LEU A:168 A:166 9.0 0.053 -116.8 -13.5 9.0 0.053 0.0 HOH
 3.112
 N
 O
LEU B:168 C:166 8.0 0.047 -116.7 -18.4 8.0 0.047 0.0 HOH
 3.084
 N
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 LEU A:166 A:166 4.0 0.024 -125.8 -18.8 4.0 0.024 0.0 HOH
 3.159
 N
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 LEU A:166 A:166 2.0 0.012 66.5 -38.9 2.0 0.012 0.0 HOH
 3.122
 O
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 LEU A:161 A:166 6.0 0.035 -110.9 -19.7 6.0 0.035 0.0 PLP
HOH
 9.837
2.308
 HD21
H
 H2A2
O
LEU B:161 B:166 6.0 0.035 -118.0 -22.6 6.0 0.035 0.0 PLP
HOH
 9.731
2.143
 HD11
H
 H2A2
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 LEU A:161 A:166 6.0 0.035 -111.5 -17.2 6.0 0.035 0.0 HOH
 2.299
 H
 O
LEU B:161 B:166 6.0 0.035 -119.3 -22.0 6.0 0.035 0.0 PLR
HOH
 9.835
2.116
 HD11
H
 H2A2
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 LEU A:166 A:166 8.0 0.047 -120.2 -19.7 8.0 0.047 0.0 HOH
 2.863
 N
 O
LEU B:166 B:166 6.0 0.035 -116.8 -21.9 6.0 0.035 0.0 GOL
HOH
 8.496
2.553
 N
O
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 LEU A:166 A:166 5.0 0.029 -113.4 -17.4