Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812399 . C A CCDS2543.1:NM_000030.2:c.528taC>taA_NP_000021.1:p.176Y>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 TYR A:176 A:176 73.0 0.317 T -81.5 27.8 73.0 0.317 0.0 HOH
 4.078
 O
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 TYR A:176 A:176 75.0 0.326 T -104.2 25.9 75.0 0.326 0.0
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TYR A:176 A:176 87.0 0.378 T -83.9 10.4 87.0 0.378 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TYR A:176 A:176 119.0 0.517 T -80.9 5.9 119.0 0.517 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 TYR A:178 A:176 76.0 0.33 T -105.3 17.7 76.0 0.33 0.0 HOH
 2.480
 O
 O
TYR C:178 C:176 77.0 0.335 T -108.5 24.6 77.0 0.335 0.0 HOH
 2.588
 O
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 TYR A:176 A:176 78.0 0.339 T -88.3 28.4 78.0 0.339 0.0 HOH
 2.777
 CE1
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 TYR A:178 A:176 74.0 0.322 T -98.5 15.7 74.0 0.322 0.0 HOH
 2.634
 O
 O
TYR B:178 C:176 85.0 0.37 T -103.0 17.8 85.0 0.37 0.0 BME
HOH
 4.182
2.687
 O
O
 S2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 TYR A:178 A:176 82.0 0.357 T -98.5 17.7 82.0 0.357 0.0
TYR B:178 B:176 88.0 0.383 T -99.3 17.2 88.0 0.383 0.0
TYR C:178 C:176 83.0 0.361 T -98.0 17.0 NA NA NA
TYR D:178 D:176 83.0 0.361 T -98.2 17.3 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 TYR A:176 A:176 77.0 0.335 T -133.8 13.6 77.0 0.335 0.0 HOH
 8.701
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 TYR A:187 A:176 56.0 0.243 T -95.5 15.4 56.0 0.243 0.0 HOH
 2.733
 O
 O
TYR B:187 B:176 84.0 0.365 T -97.6 15.9 84.0 0.365 0.0 HOH
 2.878
 O
 O
TYR C:187 E:176 81.0 0.352 T -93.3 17.2 NA NA NA
TYR D:187 G:176 85.0 0.37 T -100.2 17.7 NA NA NA
TYR E:187 M:176 81.0 0.352 T -102.4 18.1 NA NA NA
TYR F:187 N:176 76.0 0.33 T -99.8 12.5 NA NA NA
TYR G:187 S:176 83.0 0.361 T -99.4 14.1 NA NA NA
TYR H:187 T:176 67.0 0.291 T -93.7 15.7 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 TYR A:178 A:176 70.0 0.304 T -107.8 15.6 70.0 0.304 0.0
TYR B:178 C:176 66.0 0.287 T -109.8 14.7 66.0 0.287 0.0 HOH
 3.497
 CZ
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 TYR A:176 A:176 84.0 0.365 T -85.9 11.3 84.0 0.365 0.0 HOH
 2.651
 N
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 TYR A:176 A:176 90.0 0.391 G 71.0 5.7 90.0 0.391 0.0
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 TYR A:171 A:176 75.0 0.326 T -90.5 12.8 75.0 0.326 0.0 HOH
 2.487
 O
 O
TYR B:171 B:176 73.0 0.317 T -99.7 14.0 73.0 0.317 0.0 HOH
 2.282
 O
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 TYR A:171 A:176 67.0 0.291 T -88.5 11.3 67.0 0.291 0.0 HOH
 2.509
 O
 O
TYR B:171 B:176 71.0 0.309 T -95.3 15.3 71.0 0.309 0.0 HOH
 2.401
 O
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 TYR A:176 A:176 77.0 0.335 T -99.5 16.2 77.0 0.335 0.0 HOH
 2.562
 O
 O
TYR B:176 B:176 73.0 0.317 T -107.1 18.6 73.0 0.317 0.0 HOH
 2.598
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 TYR A:176 A:176 82.0 0.357 T -91.4 9.4