Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812405 . C A CCDS2543.1:NM_000030.2:c.534tgC>tgA_NP_000021.1:p.178C>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 CYS A:178 A:178 1.0 0.007 -109.0 141.6 1.0 0.007 0.0 HOH
 5.962
 N
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 CYS A:178 A:178 5.0 0.037 -86.3 161.7 5.0 0.037 0.0
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:178 A:178 0.0 0.0 -79.3 154.0 0.0 0.0 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:178 A:178 1.0 0.007 -70.6 154.7 1.0 0.007 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 CYS A:180 A:178 2.0 0.015 -114.4 149.6 2.0 0.015 0.0 HOH
 4.013
 CB
 O
CYS C:180 C:178 2.0 0.015 -107.0 147.8 2.0 0.015 0.0 HOH
 3.886
 CB
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 CYS A:178 A:178 3.0 0.022 -81.3 162.3 3.0 0.022 0.0 HOH
 4.330
 CB
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 CYS A:180 A:178 2.0 0.015 -122.5 142.1 2.0 0.015 0.0 HOH
 4.091
 CA
 O
CYS B:180 C:178 2.0 0.015 -117.9 141.8 2.0 0.015 0.0 BME
HOH
 4.947
4.222
 N
CB
 O1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 CYS A:180 A:178 8.0 0.059 -153.3 147.4 8.0 0.059 0.0
CYS B:180 B:178 6.0 0.044 -152.9 147.0 6.0 0.044 0.0
CYS C:180 C:178 8.0 0.059 -153.3 147.7 NA NA NA
CYS D:180 D:178 6.0 0.044 -152.9 147.0 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 CYS A:178 A:178 5.0 0.037 -106.9 131.8 5.0 0.037 0.0 HOH
 9.617
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 CYS A:189 A:178 4.0 0.03 -114.5 136.2 4.0 0.03 0.0 HOH
 3.660
 O
 O
CYS B:189 B:178 2.0 0.015 -115.7 141.2 2.0 0.015 0.0 HOH
 3.248
 O
 O
CYS C:189 E:178 3.0 0.022 -118.8 138.8 NA NA NA
CYS D:189 G:178 2.0 0.015 -111.7 140.2 NA NA NA
CYS E:189 M:178 2.0 0.015 -115.5 139.7 NA NA NA
CYS F:189 N:178 2.0 0.015 -114.3 137.9 NA NA NA
CYS G:189 S:178 2.0 0.015 -110.8 143.7 NA NA NA
CYS H:189 T:178 2.0 0.015 -115.4 140.5 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 CYS A:180 A:178 2.0 0.015 -118.3 147.6 2.0 0.015 0.0
CYS B:180 C:178 3.0 0.022 -134.2 140.8 3.0 0.022 0.0 HOH
 9.755
 O
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 CYS A:178 A:178 1.0 0.007 -109.5 133.8 1.0 0.007 0.0 HOH
 2.310
 SG
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 CYS A:178 A:178 1.0 0.007 -109.9 147.4 1.0 0.007 0.0 HOH
 9.670
 O
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 CYS A:173 A:178 2.0 0.015 -108.8 141.5 2.0 0.015 0.0 HOH
 2.890
 HB2
 O
CYS B:173 B:178 2.0 0.015 -114.7 142.7 2.0 0.015 0.0 HOH
 2.777
 HB2
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 CYS A:173 A:178 2.0 0.015 -110.5 141.1 2.0 0.015 0.0 HOH
 2.820
 HB2
 O
CYS B:173 B:178 3.0 0.022 -118.4 142.3 3.0 0.022 0.0 HOH
 2.882
 HB2
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 CYS A:178 A:178 3.0 0.022 -122.1 140.6 3.0 0.022 0.0 HOH
 3.903
 CA
 O
CYS B:178 B:178 3.0 0.022 -117.9 140.5 3.0 0.022 0.0 HOH
 3.314
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 CYS A:178 A:178 2.0 0.015 -101.4 140.0