Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812418 . G A CCDS2543.1:NM_000030.2:c.547Gat>Aat_NP_000021.1:p.183D>N Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ASP A:183 A:183 8.0 0.053 E -95.3 105.6 8.0 0.053 0.0 PLP
AOA
HOH
 2.827
9.817
2.924
 OD2
OD2
O
 N1
O2
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ASP A:183 A:183 7.0 0.047 E -90.6 102.9 7.0 0.047 0.0 PLP
HOH
 2.903
3.228
 OD1
O
 C2A
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:183 A:183 8.0 0.053 E -86.0 96.9 8.0 0.053 0.0 PMP
HOH
 2.921
2.538
 OD2
O
 N1
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:183 A:183 7.0 0.047 E -92.9 94.6 7.0 0.047 0.0 PLP
 3.038
 OD2
 N1
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ASP A:185 A:183 0.0 0.0 E -81.8 115.0 0.0 0.0 0.0 HOH
 2.848
 OD1
 O
ASP C:185 C:183 0.0 0.0 E -87.9 111.6 0.0 0.0 0.0 HOH
 3.089
 OD1
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ASN A:183 A:183 7.0 0.044 E -86.9 106.7 7.0 0.044 0.0 PLP
DIO
HOH
 3.156
9.917
6.680
 ND2
ND2
ND2
 N1
C2'
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ASP A:185 A:183 1.0 0.007 E -92.0 112.8 1.0 0.007 0.0 SO4
BME
HOH
 7.624
9.154
2.759
 OD2
O
OD1
 O3
O1
O
ASP B:185 C:183 1.0 0.007 E -87.8 113.2 1.0 0.007 0.0 SO4
HOH
 7.501
2.815
 OD2
OD1
 O3
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ASP A:185 A:183 0.0 0.0 E -101.3 107.9 0.0 0.0 0.0
ASP B:185 B:183 0.0 0.0 E -104.1 109.3 0.0 0.0 0.0
ASP C:185 C:183 1.0 0.007 E -102.2 106.8 NA NA NA
ASP D:185 D:183 1.0 0.007 E -102.7 108.2 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ASP A:183 A:183 1.0 0.007 E -93.0 118.2 1.0 0.007 0.0 AOA
HOH
 9.752
3.228
 OD2
OD1
 O2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ASN A:194 A:183 8.0 0.05 E -84.7 116.9 8.0 0.05 0.0 PLP
HOH
 3.044
2.957
 ND2
OD1
 N1
O
ASN B:194 B:183 8.0 0.05 E -86.8 116.7 8.0 0.05 0.0 PLP
HOH
 3.111
2.953
 ND2
OD1
 N1
O
ASN C:194 E:183 8.0 0.05 E -88.6 120.9 NA NA NA
ASN D:194 G:183 9.0 0.056 E -86.2 114.2 NA NA NA
ASN E:194 M:183 8.0 0.05 E -86.0 115.2 NA NA NA
ASN F:194 N:183 9.0 0.056 E -90.7 118.8 NA NA NA
ASN G:194 S:183 10.0 0.062 E -89.3 114.5 NA NA NA
ASN H:194 T:183 8.0 0.05 E -93.0 116.0 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ASP A:185 A:183 1.0 0.007 E -86.4 115.7 1.0 0.007 0.0 SO4
BME
HOH
 7.260
8.910
2.754
 OD2
OD2
O
 O4
C1
O
ASP B:185 C:183 1.0 0.007 E -93.8 110.2 1.0 0.007 0.0 SO4
HOH
 7.004
2.964
 OD2
OD1
 O3
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ASP A:183 A:183 6.0 0.04 E -84.9 106.4 6.0 0.04 0.0 PLP
GOL
HOH
 2.843
9.362
5.820
 OD2
OD2
OD2
 N1
O1
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ASP A:183 A:183 9.0 0.06 E -89.6 112.3 9.0 0.06 0.0 PLP
HOH
 2.684
6.575
 OD2
OD2
 N1
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ASP A:178 A:183 6.0 0.04 E -94.9 113.9 6.0 0.04 0.0 PLP
HOH
 2.595
3.039
 OD1
O
 H2A2
O
ASP B:178 B:183 5.0 0.033 E -89.7 112.6 5.0 0.033 0.0 PLP
HOH
 2.285
3.025
 OD1
O
 H2A2
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ASP A:178 A:183 6.0 0.04 E -92.1 115.1 6.0 0.04 0.0 PLR
HOH
 2.669
3.039
 OD2
O
 N1
O
ASP B:178 B:183 6.0 0.04 E -90.4 115.4 6.0 0.04 0.0 PLR
HOH
 2.336
3.105
 OD1
O
 H2A2
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ASP A:183 A:183 5.0 0.033 E -87.2 112.1 5.0 0.033 0.0 PLP
HOH
 2.696
3.075
 OD2
O
 N1
O
ASP B:183 B:183 6.0 0.04 E -87.7 114.4 6.0 0.04 0.0 PLP
HOH
 2.840
3.092
 OD2
O
 N1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ASP A:183 A:183 5.0 0.033 E -84.7 116.4