Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812428 . C A CCDS2543.1:NM_000030.2:c.557gCa>gAa_NP_000021.1:p.186A>E Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ALA A:186 A:186 2.0 0.017 T -95.4 -18.6 2.0 0.017 0.0 PLP
AOA
HOH
 3.390
7.297
3.056
 CB
CB
N
 O3
O2
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ALA A:186 A:186 1.0 0.009 T -87.0 -24.4 1.0 0.009 0.0 PLP
HOH
 3.606
2.756
 CB
N
 O3
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ALA A:186 A:186 3.0 0.026 T -100.7 15.4 3.0 0.026 0.0 PMP
HOH
 3.308
2.791
 CB
N
 O3
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ALA A:186 A:186 3.0 0.026 T -94.4 17.2 3.0 0.026 0.0 PLP
 3.170
 CB
 O3
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ALA A:188 A:186 0.0 0.0 T -93.9 -13.2 0.0 0.0 0.0 HOH
 3.064
 N
 O
ALA C:188 C:186 0.0 0.0 T -85.3 -19.8 0.0 0.0 0.0 HOH
 2.839
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ALA A:186 A:186 2.0 0.017 T -65.8 -40.2 2.0 0.017 0.0 PLP
DIO
HOH
 3.131
8.149
5.422
 CB
CB
O
 O3
C2'
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ALA A:188 A:186 2.0 0.017 T -90.0 -16.2 2.0 0.017 0.0 SO4
HOH
 7.919
3.015
 N
N
 O4
O
ALA B:188 C:186 1.0 0.009 T -94.6 -20.1 1.0 0.009 0.0 SO4
HOH
 7.971
3.106
 N
N
 O1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ALA A:188 A:186 0.0 0.0 -96.8 7.9 0.0 0.0 0.0
ALA B:188 B:186 0.0 0.0 -98.1 8.4 0.0 0.0 0.0
ALA C:188 C:186 0.0 0.0 -95.5 7.6 NA NA NA
ALA D:188 D:186 0.0 0.0 -98.1 8.4 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ALA A:186 A:186 1.0 0.009 T -90.2 -20.1 1.0 0.009 0.0 AOA
HOH
 7.389
2.951
 CB
N
 O2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ALA A:197 A:186 1.0 0.009 T -95.0 -12.4 1.0 0.009 0.0 PLP
HOH
 3.202
3.033
 CB
N
 O3
O
ALA B:197 B:186 1.0 0.009 T -90.1 -19.3 1.0 0.009 0.0 PLP
HOH
 3.336
3.027
 CB
N
 O3
O
ALA C:197 E:186 2.0 0.017 T -94.9 -12.2 NA NA NA
ALA D:197 G:186 1.0 0.009 T -90.6 -15.8 NA NA NA
ALA E:197 M:186 1.0 0.009 T -93.5 -11.3 NA NA NA
ALA F:197 N:186 1.0 0.009 T -92.3 -15.4 NA NA NA
ALA G:197 S:186 2.0 0.017 T -90.8 -18.0 NA NA NA
ALA H:197 T:186 2.0 0.017 T -91.9 -20.0 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ALA A:188 A:186 1.0 0.009 T -99.3 -12.7 1.0 0.009 0.0 SO4
BME
HOH
 7.642
6.430
3.310
 N
CB
N
 O4
O1
O
ALA B:188 C:186 1.0 0.009 T -93.6 -23.7 1.0 0.009 0.0 SO4
HOH
 7.853
4.024
 N
N
 O3
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ALA A:186 A:186 1.0 0.009 T -83.8 -18.7 1.0 0.009 0.0 PLP
GOL
HOH
 3.436
7.469
3.588
 CB
CB
C
 O3
O1
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ALA A:186 A:186 2.0 0.017 T -80.1 -29.3 2.0 0.017 0.0 PLP
HOH
 3.647
3.547
 CB
O
 O3
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ALA A:181 A:186 1.0 0.009 T -93.4 -19.8 1.0 0.009 0.0 PLP
HOH
 2.438
2.147
 HB2
H
 H2A1
O
ALA B:181 B:186 1.0 0.009 T -93.4 -15.9 1.0 0.009 0.0 PLP
HOH
 2.459
2.285
 HB2
H
 O3
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ALA A:181 A:186 1.0 0.009 T -93.2 -17.5 1.0 0.009 0.0 PLR
HOH
 2.507
2.069
 HB2
H
 H2A1
O
ALA B:181 B:186 1.0 0.009 T -92.2 -14.3 1.0 0.009 0.0 PLR
HOH
 2.522
2.263
 HB2
H
 H2A1
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ALA A:186 A:186 1.0 0.009 T -89.7 -19.7 1.0 0.009 0.0 PLP
HOH
 3.532
3.018
 CB
N
 O3
O
ALA B:186 B:186 1.0 0.009 T -94.7 -16.2 1.0 0.009 0.0 PLP
HOH
 3.539
2.987
 CB
N
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ALA A:186 A:186 1.0 0.009 T -94.5 -11.2