Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812431 . C A CCDS2543.1:NM_000030.2:c.560tCc>tAc_NP_000021.1:p.187S>Y Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 SER A:187 A:187 0.0 0.0 T -89.3 -30.9 0.0 0.0 0.0 PLP
HOH
 5.883
3.331
 N
N
 C2A
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 SER A:187 A:187 0.0 0.0 T -92.6 -29.4 0.0 0.0 0.0 PLP
HOH
 5.806
2.953
 N
N
 C2A
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 SER A:187 A:187 0.0 0.0 T -130.6 -43.7 0.0 0.0 0.0 PMP
HOH
 6.108
3.675
 N
N
 C2A
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 SER A:187 A:187 0.0 0.0 T -129.8 -43.0 0.0 0.0 0.0 PLP
 6.057
 N
 C2A
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 SER A:189 A:187 0.0 0.0 T -95.2 -37.4 0.0 0.0 0.0 HOH
 3.720
 N
 O
SER C:189 C:187 0.0 0.0 T -92.2 -31.1 0.0 0.0 0.0 HOH
 3.495
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 SER A:187 A:187 0.0 0.0 T -89.7 -35.5 0.0 0.0 0.0 PLP
HOH
 5.694
6.149
 N
C
 O3
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 SER A:189 A:187 0.0 0.0 T -101.8 -27.3 0.0 0.0 0.0 BME
HOH
 7.391
3.838
 CB
N
 O1
O
SER B:189 C:187 0.0 0.0 T -90.5 -31.7 0.0 0.0 0.0 HOH
 3.698
 N
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 PHE A:189 A:187 1.0 0.005 S -74.5 -15.5 1.0 0.005 0.0
PHE B:189 B:187 1.0 0.005 S -73.1 -16.5 1.0 0.005 0.0
PHE C:189 C:187 1.0 0.005 S -75.5 -13.4 NA NA NA
PHE D:189 D:187 1.0 0.005 S -74.1 -14.4 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 SER A:187 A:187 0.0 0.0 T -92.3 -34.8 0.0 0.0 0.0 HOH
 3.297
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 SER A:198 A:187 0.0 0.0 T -95.1 -33.8 0.0 0.0 0.0 PLP
HOH
 6.188
3.695
 N
N
 C2A
O
SER B:198 B:187 0.0 0.0 T -97.8 -27.3 0.0 0.0 0.0 PLP
HOH
 6.294
3.687
 N
N
 C2A
O
SER C:198 E:187 0.0 0.0 T -96.7 -32.2 NA NA NA
SER D:198 G:187 0.0 0.0 T -98.0 -31.9 NA NA NA
SER E:198 M:187 0.0 0.0 T -95.6 -33.4 NA NA NA
SER F:198 N:187 0.0 0.0 T -91.8 -31.1 NA NA NA
SER G:198 S:187 0.0 0.0 T -91.3 -32.7 NA NA NA
SER H:198 T:187 0.0 0.0 T -90.0 -33.6 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 SER A:189 A:187 0.0 0.0 T -100.8 -26.8 0.0 0.0 0.0 BME
HOH
 9.791
3.930
 N
N
 C1
O
SER B:189 C:187 0.0 0.0 T -89.2 -29.7 0.0 0.0 0.0 HOH
 6.271
 N
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 SER A:187 A:187 0.0 0.0 T -97.6 -28.2 0.0 0.0 0.0 PLP
HOH
 6.413
3.931
 N
N
 O3
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 SER A:187 A:187 0.0 0.0 T -85.9 -27.1 0.0 0.0 0.0 PLP
HOH
 6.401
4.200
 N
N
 C2A
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 SER A:182 A:187 0.0 0.0 T -90.4 -29.2 0.0 0.0 0.0 PLP
HOH
 4.797
2.788
 H
H
 H2A2
O
SER B:182 B:187 0.0 0.0 T -94.4 -31.3 0.0 0.0 0.0 PLP
HOH
 4.764
2.879
 H
H
 H2A2
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 SER A:182 A:187 0.0 0.0 T -95.0 -26.2 0.0 0.0 0.0 PLR
HOH
 4.823
2.880
 H
H
 H2A2
O
SER B:182 B:187 0.0 0.0 T -95.7 -28.8 0.0 0.0 0.0 PLR
HOH
 4.712
2.865
 H
H
 H2A2
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 SER A:187 A:187 0.0 0.0 T -95.2 -24.0 0.0 0.0 0.0 PLP
HOH
 5.928
3.592
 N
N
 C2A
O
SER B:187 B:187 0.0 0.0 T -96.7 -30.0 0.0 0.0 0.0 PLP
HOH
 6.055
3.587
 N
N
 C2A
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 SER A:187 A:187 0.0 0.0 T -101.9 -33.4