Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241812461 . G A CCDS2543.1:NM_000030.2:c.590cGg>cAg_NP_000021.1:p.197R>Q Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ARG A:197 A:197 226.0 1.0 T -50.5 -18.1 118.0 0.524 0.476 A:P21549:0.48
 HOH
 2.913
 N
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ARG A:197 A:197 93.0 NA T -57.8 -21.8 77.0 NA NA A:P21549:NA
 HOH
 5.112
 CB
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:197 A:197 187.0 0.831 T -52.7 -38.9 165.0 0.733 0.098 A:P21549:0.098
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:197 A:197 89.0 NA G -75.2 -20.4 89.0 NA NA
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ARG A:199 A:197 192.0 0.853 T -58.8 -39.2 137.0 0.609 0.244 C:P21549:0.244
 HOH
 2.919
 N
 O
ARG C:199 C:197 183.0 0.813 T -52.9 -34.9 180.0 0.8 0.013 A:P21549:0.013
 HOH
 2.651
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ARG A:197 A:197 154.0 0.684 G -61.7 -8.7 149.0 0.662 0.022 A:P21549:0.022
 HOH
 8.440
 N
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ARG A:199 A:197 185.0 0.822 T -69.5 -31.7 182.0 0.809 0.013 B:P21549:0.013
 BME
HOH
 6.633
2.704
 NH2
NH2
 S2
O
ARG B:199 C:197 196.0 0.871 T -61.2 -34.7 178.0 0.791 0.08 A:P21549:0.08
 HOH
 2.783
 O
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ARG A:199 A:197 192.0 0.853 H -60.5 -47.8 165.0 0.733 0.12 B:P21549:0.12
ARG B:199 B:197 202.0 0.898 H -67.4 -41.5 167.0 0.742 0.156 A:P21549:0.156
ARG C:199 C:197 195.0 0.867 H -61.5 -46.7 NA NA NA
ARG D:199 D:197 93.0 NA H -64.2 -44.9 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ARG A:197 A:197 161.0 0.716 T -44.4 -41.0 161.0 0.716 0.0 GOL
HOH
 3.820
2.806
 CG
NH2
 O3
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ARG A:208 A:197 190.0 0.844 T -56.9 -34.6 120.0 0.533 0.311 B:P21549:0.311
 HOH
 2.892
 N
 O
ARG B:208 B:197 180.0 0.8 T -69.5 -25.8 110.0 0.489 0.311 A:P21549:0.311
 HOH
 2.673
 NE
 O
ARG C:208 E:197 188.0 0.836 T -59.1 -30.6 NA NA NA
ARG D:208 G:197 188.0 0.836 T -65.1 -30.8 NA NA NA
ARG E:208 M:197 185.0 0.822 T -64.6 -25.9 NA NA NA
ARG F:208 N:197 183.0 0.813 T -63.2 -29.8 NA NA NA
ARG G:208 S:197 184.0 0.818 T -61.7 -30.0 NA NA NA
ARG H:208 T:197 183.0 0.813 T -59.9 -31.3 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ARG A:199 A:197 193.0 0.858 T -59.1 -37.5 186.0 0.827 0.031 B:P21549:0.031
 HOH
 3.146
 NE
 O
ARG B:199 C:197 186.0 0.827 T -46.0 -34.4 174.0 0.773 0.054 A:P21549:0.053
 HOH
 8.427
 NH2
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ARG A:197 A:197 184.0 0.818 T -60.2 -29.4 111.0 0.493 0.325 A:P21549:0.324
 HOH
 3.277
 CD
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ARG A:197 A:197 164.0 0.729 T -52.8 -30.1 137.0 0.609 0.12 A:P21549:0.12
 HOH
 2.441
 N
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ARG A:192 A:197 187.0 0.831 T -62.4 -35.7 165.0 0.733 0.098 B:P21549:0.098
 HOH
 2.067
 HH11
 O
ARG B:192 B:197 158.0 0.702 T -53.6 -43.5 156.0 0.693 0.009 A:P21549:0.009
 HOH
 2.077
 H
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ARG A:192 A:197 188.0 0.836 T -61.1 -36.7 166.0 0.738 0.098 B:P21549:0.098
 HOH
 1.909
 HH11
 O
ARG B:192 B:197 160.0 0.711 T -50.9 -42.7 160.0 0.711 0.0 HOH
 2.100
 H
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ARG A:197 A:197 163.0 0.724 T -61.8 -33.8 116.0 0.516 0.208 B:P21549:0.209
 GOL
HOH
 6.601
2.831
 N
N
 O3
O
ARG B:197 B:197 201.0 0.893 T -60.8 -35.6 131.0 0.582 0.311 A:P21549:0.311
 SO4
HOH
 2.554
2.881
 NH1
N
 O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ARG A:197 A:197 197.0 0.876 T -65.4 -36.5