Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 241813426 | . | G | A | CCDS2543.1:NM_000030.2:c.627aaG>aaA_NP_000021.1:p.209K>K | Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1h0c | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2003-06-12 | LYS | A:209 | A:209 | 27.0 | 0.135 | S | -97.3 | -123.4 | 16.0 | 0.08 | 0.055 |
A:P21549:0.055 |
PLP AOA GOL HOH |
1.338 3.446 9.995 2.888 |
NZ NZ O N |
C4A O1 O3 O |
|
| 5og0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-09-27 | LYS | A:209 | A:209 | 20.0 | 0.1 | S | -100.6 | -119.8 | 13.0 | 0.065 | 0.035 |
A:P21549:0.035 |
PLP HOH |
1.490 2.974 |
NZ N |
C4A O |
|
| 6rv0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | LYS | A:209 | A:209 | 13.0 | 0.065 | S | -100.3 | -113.7 | 13.0 | 0.065 | 0.0 |
PMP HOH |
3.300 4.878 |
CE N |
O3 O |
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| 6rv1 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | LYS | A:209 | A:209 | 23.0 | 0.115 | S | -101.1 | -110.0 | 15.0 | 0.075 | 0.04 |
A:P21549:0.04 |
PLP |
1.294 |
NZ |
C4A |
|
| 3r9a | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2011-05-11 | LLP | A:211 | A:209 | NA | NA | NA | NA | NA | NA | NA | NA |
HOH |
2.824 |
OP1 |
O |
||
| LLP | C:211 | C:209 | NA | NA | NA | NA | NA | NA | NA | NA |
HOH |
3.075 |
C2' |
O |
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| 5ofy | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-27 | LYS | A:209 | A:209 | 19.0 | 0.095 | S | -87.5 | -119.7 | 18.0 | 0.09 | 0.005 |
A:P21549:0.005 |
PLP DIO HOH |
1.448 3.802 3.266 |
NZ NZ C |
C4A C2' O |
|
| 4kyo | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2014-11-19 | LYS | A:211 | A:209 | 16.0 | 0.08 | S | -99.8 | -110.0 | 13.0 | 0.065 | 0.015 |
B:P21549:0.015 |
SO4 HOH |
5.184 2.861 |
NZ NZ |
O4 O |
|
| LYS | B:211 | C:209 | 16.0 | 0.08 | S | -93.1 | -113.1 | 15.0 | 0.075 | 0.005 |
A:P21549:0.005 |
SO4 BME HOH |
5.275 9.631 2.598 |
CE NZ NZ |
O1 O1 O |
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| 4i8a | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-05-01 | LLP | A:211 | A:209 | NA | NA | NA | NA | NA | NA | NA | NA |
GOL |
4.402 |
C4' |
C1 |
||
| LLP | B:211 | B:209 | NA | NA | NA | NA | NA | NA | NA | NA |
GOL |
3.778 |
CE |
C3 |
|||||||||
| LLP | C:211 | C:209 | NA | NA | NA | NA | NA | NA | NA | NA | |||||||||||||
| LLP | D:211 | D:209 | NA | NA | NA | NA | NA | NA | NA | NA | |||||||||||||
| 1j04 | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2003-11-11 | LLP | A:209 | A:209 | NA | NA | NA | NA | NA | NA | NA | NA |
AOA HOH |
3.554 2.883 |
C4' N |
O2 O |
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| 5luc | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-20 | LYS | A:220 | A:209 | 18.0 | 0.09 | S | -99.5 | -117.4 | 17.0 | 0.085 | 0.005 |
B:P21549:0.005 |
PLP HOH |
1.407 3.037 |
NZ N |
C4A O |
|
| LYS | B:220 | B:209 | 18.0 | 0.09 | S | -95.4 | -118.9 | 18.0 | 0.09 | 0.0 |
PLP HOH |
1.397 3.069 |
NZ N |
C4A O |
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| LYS | C:220 | E:209 | 19.0 | 0.095 | S | -96.9 | -117.2 | NA | NA | NA | |||||||||||||
| LYS | D:220 | G:209 | 18.0 | 0.09 | S | -96.8 | -114.5 | NA | NA | NA | |||||||||||||
| LYS | E:220 | M:209 | 18.0 | 0.09 | S | -98.3 | -111.8 | NA | NA | NA | |||||||||||||
| LYS | F:220 | N:209 | 18.0 | 0.09 | S | -96.8 | -112.6 | NA | NA | NA | |||||||||||||
| LYS | G:220 | S:209 | 18.0 | 0.09 | S | -100.7 | -116.0 | NA | NA | NA | |||||||||||||
| LYS | H:220 | T:209 | 18.0 | 0.09 | S | -99.8 | -116.9 | NA | NA | NA | |||||||||||||
| 4kxk | 1 | P21549 | 99.49 | 0.0 |
X-RAY |
2014-11-19 | LYS | A:211 | A:209 | 13.0 | 0.065 | S | -95.4 | -108.6 | 13.0 | 0.065 | 0.0 |
SO4 BME HOH |
4.820 3.205 6.712 |
NZ NZ O |
O4 C1 O |
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| LYS | B:211 | C:209 | 15.0 | 0.075 | S | -96.7 | -111.3 | 14.0 | 0.07 | 0.005 |
A:P21549:0.005 |
SO4 HOH |
5.371 3.336 |
NZ NZ |
O3 O |
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| 4cbr | 1 | P21549 | 99.23 | 0.0 |
X-RAY |
2014-07-09 | LYS | A:209 | A:209 | 17.0 | 0.085 | S | -94.1 | -120.5 | 15.0 | 0.075 | 0.01 |
A:P21549:0.01 |
PLP GOL HOH |
1.358 3.544 2.990 |
NZ CE N |
C4A O1 O |
|
| 4cbs | 1 | P21549 | 98.72 | 0.0 |
X-RAY |
2014-07-09 | LYS | A:209 | A:209 | 22.0 | 0.11 | S | -97.8 | -118.9 | 14.0 | 0.07 | 0.04 |
A:P21549:0.04 |
PLP HOH |
1.386 3.074 |
NZ NZ |
C4A O |
|
| 5f9s | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2016-12-21 | LYS | A:204 | A:209 | 21.0 | 0.105 | S | -95.5 | -120.9 | 15.0 | 0.075 | 0.03 |
B:P21549:0.03 |
PLP HOH |
1.474 2.468 |
NZ HE3 |
C4A O |
|
| LYS | B:204 | B:209 | 19.0 | 0.095 | S | -94.9 | -118.8 | 14.0 | 0.07 | 0.025 |
A:P21549:0.025 |
PLP HOH |
1.458 2.486 |
NZ HE3 |
C4A O |
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| 5hhy | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | LYS | A:204 | A:209 | 19.0 | 0.095 | S | -99.6 | -119.5 | 18.0 | 0.09 | 0.005 |
B:P21549:0.005 |
PLR HOH |
1.794 2.400 |
HZ1 H |
H4A2 O |
|
| LYS | B:204 | B:209 | 18.0 | 0.09 | S | -96.5 | -117.0 | 17.0 | 0.085 | 0.005 |
A:P21549:0.005 |
PLR HOH |
1.533 2.346 |
HZ3 HB2 |
H4A2 O |
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| 2yob | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-10-30 | LYS | A:209 | A:209 | 19.0 | 0.095 | S | -93.3 | -114.9 | 13.0 | 0.065 | 0.03 |
B:P21549:0.03 |
PLP HOH |
1.388 3.132 |
NZ N |
C4A O |
|
| LYS | B:209 | B:209 | 22.0 | 0.11 | S | -94.6 | -120.4 | 17.0 | 0.085 | 0.025 |
A:P21549:0.025 |
PLP HOH |
1.379 3.095 |
NZ CB |
C4A O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p21549-f1 | 1 | P21549 | 100.0 | 0.0 | LYS | A:209 | A:209 | 15.0 | 0.075 | S | -97.3 | -123.8 | |