Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241813445 . G A CCDS2543.1:NM_000030.2:c.646Ggg>Agg_NP_000021.1:p.216G>R Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 GLY A:216 A:216 30.0 0.4 T 123.0 -23.1 11.0 0.147 0.253 A:P21549:0.253
 PLP
HOH
 5.621
2.937
 N
CA
 O2P
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 GLY A:216 A:216 31.0 0.413 S 126.8 -9.2 14.0 0.187 0.226 A:P21549:0.227
 PLP
HOH
 5.830
2.978
 N
N
 O2P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 GLY A:216 A:216 32.0 0.427 S 112.0 2.1 14.0 0.187 0.24 A:P21549:0.24
 PMP
HOH
 5.891
3.142
 N
N
 O2P
O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 GLY A:216 A:216 32.0 0.427 S 104.8 1.7 14.0 0.187 0.24 A:P21549:0.24
 PLP
 6.108
 N
 O2P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 GLY A:218 A:216 32.0 0.427 T 128.6 -24.1 12.0 0.16 0.267 C:P21549:0.267
 HOH
 2.960
 N
 O
GLY C:218 C:216 32.0 0.427 S 129.4 -19.0 13.0 0.173 0.254 A:P21549:0.253
 HOH
 2.725
 N
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 GLY A:216 A:216 30.0 0.4 S 115.9 -2.5 14.0 0.187 0.213 A:P21549:0.213
 PLP
HOH
 5.869
2.883
 N
N
 O3P
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 GLY A:218 A:216 31.0 0.413 S 136.8 -12.3 15.0 0.2 0.213 B:P21549:0.213
 SO4
BME
BME
HOH
 6.566
7.905
9.382
2.611
 N
CA
O
O
 O2
C2
S2
O
GLY B:218 C:216 25.0 0.333 S 143.0 -16.4 14.0 0.187 0.146 A:P21549:0.147
 SO4
BME
BME
HOH
 6.723
4.749
8.207
2.641
 N
N
O
O
 O4
O1
C2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 GLY A:218 A:216 33.0 0.44 S 112.0 -6.6 14.0 0.187 0.253 B:P21549:0.253
GLY B:218 B:216 32.0 0.427 S 111.1 -4.3 14.0 0.187 0.24 A:P21549:0.24
GLY C:218 C:216 34.0 0.453 S 111.6 -5.2 NA NA NA
GLY D:218 D:216 33.0 0.44 S 111.8 -6.2 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 GLY A:216 A:216 35.0 0.467 T 127.2 -26.1 35.0 0.467 0.0 HOH
 2.785
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 GLY A:227 A:216 32.0 0.427 T 141.2 -24.3 18.0 0.24 0.187 B:P21549:0.187
 PLP
HOH
 6.025
2.845
 N
N
 O3P
O
GLY B:227 B:216 30.0 0.4 S 141.4 -13.4 15.0 0.2 0.2 A:P21549:0.2
 PLP
HOH
 6.115
2.717
 N
O
 O1P
O
GLY C:227 E:216 30.0 0.4 T 133.8 -18.1 NA NA NA
GLY D:227 G:216 31.0 0.413 S 135.7 -19.0 NA NA NA
GLY E:227 M:216 32.0 0.427 T 137.9 -18.3 NA NA NA
GLY F:227 N:216 33.0 0.44 S 135.9 -15.5 NA NA NA
GLY G:227 S:216 31.0 0.413 T 136.2 -14.8 NA NA NA
GLY H:227 T:216 31.0 0.413 S 136.9 -9.6 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 GLY A:218 A:216 29.0 0.387 T 146.7 -29.5 12.0 0.16 0.227 B:P21549:0.227
 SO4
 6.319
 N
 O1
GLY B:218 C:216 32.0 0.427 T 149.6 -35.9 13.0 0.173 0.254 A:P21549:0.253
 SO4
 6.345
 N
 O1
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 GLY A:216 A:216 31.0 0.413 T 131.6 -18.6 14.0 0.187 0.226 A:P21549:0.227
 PLP
HOH
 6.004
2.677
 N
N
 O3P
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 GLY A:216 A:216 32.0 0.427 T 134.2 -24.0 14.0 0.187 0.24 A:P21549:0.24
 PLP
HOH
 6.178
2.765
 N
O
 O2P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 GLY A:211 A:216 33.0 0.44 S 133.9 -14.5 17.0 0.227 0.213 B:P21549:0.213
 PLP
HOH
 5.158
1.980
 H
H
 O3P
O
GLY B:211 B:216 35.0 0.467 T 127.6 -11.5 15.0 0.2 0.267 A:P21549:0.267
 PLP
HOH
 5.137
1.855
 H
H
 O1P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 GLY A:211 A:216 33.0 0.44 T 135.8 -18.2 17.0 0.227 0.213 B:P21549:0.213
 PLR
HOH
 5.163
1.834
 H
H
 O3P
O
GLY B:211 B:216 35.0 0.467 S 130.3 -10.3 15.0 0.2 0.267 A:P21549:0.267
 PLR
HOH
 5.177
1.907
 H
H
 O1P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 GLY A:216 A:216 32.0 0.427 S 137.3 -21.2 16.0 0.213 0.214 B:P21549:0.213
 PLP
HOH
 5.853
2.799
 N
O
 O3P
O
GLY B:216 B:216 31.0 0.413 S 141.2 -17.3 15.0 0.2 0.213 A:P21549:0.213
 PLP
HOH
 5.895
2.632
 N
O
 O1P
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 GLY A:216 A:216 31.0 0.413 T 136.8 -12.5