Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241814572 . G A CCDS2543.1:NM_000030.2:c.727Gac>Aac_NP_000021.1:p.243D>N Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ASP A:243 A:243 11.0 0.073 -70.8 110.2 2.0 0.013 0.06 A:P21549:0.06
 GOL
HOH
 9.901
2.796
 CG
OD2
 O2
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ASP A:243 A:243 19.0 0.127 -71.5 121.1 3.0 0.02 0.107 A:P21549:0.107
 HOH
 6.424
 N
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:243 A:243 13.0 0.087 -65.8 120.7 5.0 0.033 0.054 A:P21549:0.053
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:243 A:243 23.0 0.153 -59.6 116.2 12.0 0.08 0.073 A:P21549:0.073
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ASP A:245 A:243 16.0 0.107 -64.1 116.1 6.0 0.04 0.067 C:P21549:0.067
 HOH
 2.907
 OD2
 O
ASP C:245 C:243 14.0 0.093 -61.1 116.7 4.0 0.027 0.066 A:P21549:0.067
 BTB
HOH
 5.498
3.215
 OD1
OD1
 O3
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ASP A:243 A:243 20.0 0.133 -65.5 117.0 12.0 0.08 0.053 A:P21549:0.053
 HOH
 5.936
 OD1
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ASP A:245 A:243 15.0 0.1 -64.1 111.7 6.0 0.04 0.06 B:P21549:0.06
 BTB
HOH
 4.994
3.227
 OD1
OD2
 C6
O
ASP B:245 C:243 14.0 0.093 -66.9 114.2 6.0 0.04 0.053 A:P21549:0.053
 BTB
BME
HOH
 5.744
6.401
3.106
 OD1
N
OD2
 C4
S2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ASP A:245 A:243 23.0 0.153 -64.8 119.7 9.0 0.06 0.093 B:P21549:0.093
ASP B:245 B:243 24.0 0.16 -63.5 119.8 10.0 0.067 0.093 A:P21549:0.093
ASP C:245 C:243 24.0 0.16 -65.6 120.0 NA NA NA
ASP D:245 D:243 23.0 0.153 -64.1 119.3 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ASP A:243 A:243 21.0 0.14 -60.9 128.1 21.0 0.14 0.0 HOH
 2.923
 OD2
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ASP A:254 A:243 17.0 0.113 -68.7 119.6 6.0 0.04 0.073 B:P21549:0.073
 BTB
HOH
 5.232
2.877
 OD1
OD2
 C6
O
ASP B:254 B:243 16.0 0.107 -61.5 120.3 6.0 0.04 0.067 A:P21549:0.067
 BTB
HOH
 5.219
2.794
 OD1
OD2
 C6
O
ASP C:254 E:243 18.0 0.12 -66.5 118.7 NA NA NA
ASP D:254 G:243 17.0 0.113 -65.3 121.1 NA NA NA
ASP E:254 M:243 18.0 0.12 -65.8 120.3 NA NA NA
ASP F:254 N:243 20.0 0.133 -62.8 121.1 NA NA NA
ASP G:254 S:243 18.0 0.12 -65.4 121.3 NA NA NA
ASP H:254 T:243 17.0 0.113 -70.0 120.4 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ASP A:245 A:243 16.0 0.107 -62.2 115.2 8.0 0.053 0.054 B:P21549:0.053
ASP B:245 C:243 15.0 0.1 -55.5 122.1 6.0 0.04 0.06 A:P21549:0.06
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ASP A:243 A:243 18.0 0.12 -67.6 120.5 5.0 0.033 0.087 A:P21549:0.087
 HOH
 5.956
 N
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ASP A:243 A:243 20.0 0.133 -71.9 124.8 7.0 0.047 0.086 A:P21549:0.087
 HOH
 6.139
 OD2
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ASP A:238 A:243 12.0 0.08 -66.4 121.5 4.0 0.027 0.053 B:P21549:0.053
 HOH
 2.706
 OD2
 O
ASP B:238 B:243 15.0 0.1 -65.5 122.4 6.0 0.04 0.06 A:P21549:0.06
 HOH
 2.718
 OD2
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ASP A:238 A:243 14.0 0.093 -66.4 120.5 5.0 0.033 0.06 B:P21549:0.06
 HOH
 2.765
 OD2
 O
ASP B:238 B:243 15.0 0.1 -67.3 120.9 6.0 0.04 0.06 A:P21549:0.06
 HOH
 2.882
 OD2
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ASP A:243 A:243 16.0 0.107 -62.3 119.2 5.0 0.033 0.074 B:P21549:0.073
 BTB
HOH
 4.740
3.143
 OD1
OD1
 O8
O
ASP B:243 B:243 15.0 0.1 -67.4 120.4 6.0 0.04 0.06 A:P21549:0.06
 BTB
GOL
HOH
 4.585
5.516
2.908
 OD1
OD2
OD2
 O8
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ASP A:243 A:243 17.0 0.113 -63.8 118.0