Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241814576 . T A CCDS2543.1:NM_000030.2:c.731aTc>aAc_NP_000021.1:p.244I>N Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ILE A:244 A:244 4.0 0.023 H -59.4 -26.7 4.0 0.023 0.0 HOH
 4.501
 O
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ILE A:244 A:244 4.0 0.023 H -63.6 -29.5 4.0 0.023 0.0 HOH
 4.751
 O
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ILE A:244 A:244 2.0 0.011 H -67.1 -31.6 2.0 0.011 0.0 HOH
 9.067
 CG1
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ILE A:244 A:244 5.0 0.029 H -63.7 -37.9 5.0 0.029 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ILE A:246 A:244 2.0 0.011 H -64.7 -30.1 2.0 0.011 0.0 HOH
 4.693
 CG2
 O
ILE C:246 C:244 0.0 0.0 H -62.7 -34.0 0.0 0.0 0.0 BTB
HOH
 6.988
3.392
 O
CG2
 C7
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ILE A:244 A:244 7.0 0.04 H -64.0 -34.2 7.0 0.04 0.0 HOH
 6.855
 O
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ILE A:246 A:244 1.0 0.006 H -65.9 -29.1 1.0 0.006 0.0 BTB
HOH
 6.763
4.023
 C
CG2
 C6
O
ILE B:246 C:244 1.0 0.006 H -65.1 -33.9 1.0 0.006 0.0 BTB
BME
HOH
 6.829
7.483
4.818
 O
CD1
O
 C6
C1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ILE A:246 A:244 1.0 0.006 H -68.6 -33.5 1.0 0.006 0.0
ILE B:246 B:244 2.0 0.011 H -70.6 -32.6 2.0 0.011 0.0
ILE C:246 C:244 2.0 0.011 H -70.3 -34.7 NA NA NA
ILE D:246 D:244 1.0 0.006 H -71.2 -32.5 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ILE A:244 A:244 3.0 0.017 H -73.8 -25.2 3.0 0.017 0.0 HOH
 4.815
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ILE A:255 A:244 3.0 0.017 H -68.2 -24.6 3.0 0.017 0.0 BTB
HOH
 6.958
3.510
 C
CG2
 C5
O
ILE B:255 B:244 1.0 0.006 H -70.1 -25.0 1.0 0.006 0.0 BTB
HOH
 6.895
3.410
 C
CG2
 C6
O
ILE C:255 E:244 3.0 0.017 H -67.1 -24.3 NA NA NA
ILE D:255 G:244 2.0 0.011 H -73.0 -24.9 NA NA NA
ILE E:255 M:244 2.0 0.011 H -70.8 -23.7 NA NA NA
ILE F:255 N:244 3.0 0.017 H -69.9 -27.0 NA NA NA
ILE G:255 S:244 1.0 0.006 H -69.7 -28.1 NA NA NA
ILE H:255 T:244 3.0 0.017 H -66.6 -28.3 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ILE A:246 A:244 2.0 0.011 H -71.4 -26.1 2.0 0.011 0.0
ILE B:246 C:244 2.0 0.011 H -74.1 -29.2 2.0 0.011 0.0 HOH
 9.378
 CG1
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ILE A:244 A:244 4.0 0.023 H -67.9 -28.0 4.0 0.023 0.0 HOH
 4.752
 O
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ILE A:244 A:244 2.0 0.011 H -68.9 -32.2 2.0 0.011 0.0 HOH
 5.065
 O
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ILE A:239 A:244 1.0 0.006 H -72.7 -27.1 1.0 0.006 0.0 HOH
 2.870
 HG22
 O
ILE B:239 B:244 0.0 0.0 H -72.2 -27.1 0.0 0.0 0.0 HOH
 3.001
 HG22
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ILE A:239 A:244 1.0 0.006 H -71.9 -27.2 1.0 0.006 0.0 HOH
 2.923
 HG22
 O
ILE B:239 B:244 1.0 0.006 H -70.2 -29.4 1.0 0.006 0.0 HOH
 3.356
 HG22
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ILE A:244 A:244 0.0 0.0 H -68.1 -28.7 0.0 0.0 0.0 BTB
HOH
 6.811
4.732
 C
O
 C7
O
ILE B:244 B:244 1.0 0.006 H -70.2 -26.5 1.0 0.006 0.0 BTB
GOL
HOH
 6.960
9.031
3.781
 C
N
CG2
 C8
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ILE A:244 A:244 1.0 0.006 H -65.8 -23.5