Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241814583 . G A CCDS2543.1:NM_000030.2:c.738tgG>tgA_NP_000021.1:p.246W>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 TRP A:246 A:246 81.0 0.318 H -75.9 -46.4 52.0 0.204 0.114 A:P21549:0.114
 GOL
HOH
 4.031
3.869
 CZ2
CD2
 C1
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 TRP A:246 A:246 86.0 0.337 H -62.4 -48.9 55.0 0.216 0.121 A:P21549:0.122
 HOH
 4.702
 N
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:246 A:246 88.0 0.345 H -66.5 -52.3 55.0 0.216 0.129 A:P21549:0.129
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:246 A:246 101.0 0.396 H -68.4 -59.2 72.0 0.282 0.114 A:P21549:0.114
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 TRP A:248 A:246 86.0 0.337 H -65.0 -51.3 59.0 0.231 0.106 C:P21549:0.106
 HOH
 2.762
 O
 O
TRP C:248 C:246 109.0 0.427 H -66.2 -49.8 80.0 0.314 0.113 A:P21549:0.114
 BTB
HOH
 3.069
3.011
 O
NE1
 O8
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 TRP A:246 A:246 88.0 0.345 H -64.7 -53.5 59.0 0.231 0.114 A:P21549:0.114
 HOH
 2.934
 CE2
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 TRP A:248 A:246 87.0 0.341 H -60.9 -48.5 61.0 0.239 0.102 B:P21549:0.102
 BTB
HOH
 3.529
2.911
 NE1
O
 C6
O
TRP B:248 C:246 93.0 0.365 H -68.5 -47.8 66.0 0.259 0.106 A:P21549:0.106
 BTB
BME
HOH
 3.098
7.427
3.293
 CA
C
NE1
 C6
C1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 TRP A:248 A:246 101.0 0.396 H -59.6 -46.0 73.0 0.286 0.11 B:P21549:0.11
TRP B:248 B:246 103.0 0.404 H -60.5 -44.8 75.0 0.294 0.11 A:P21549:0.11
 GOL
 3.904
 CH2
 C3
TRP C:248 C:246 106.0 0.416 H -60.1 -45.5 NA NA NA
TRP D:248 D:246 99.0 0.388 H -59.2 -45.0 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 TRP A:246 A:246 82.0 0.322 H -69.1 -49.4 82.0 0.322 0.0 HOH
 3.634
 NE1
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 TRP A:257 A:246 91.0 0.357 H -68.8 -48.0 62.0 0.243 0.114 B:P21549:0.114
 BTB
HOH
 3.320
3.060
 CZ2
O
 C8
O
TRP B:257 B:246 95.0 0.373 H -69.4 -45.5 64.0 0.251 0.122 A:P21549:0.122
 BTB
HOH
 3.469
3.027
 CZ2
O
 C8
O
TRP C:257 E:246 90.0 0.353 H -67.8 -49.1 NA NA NA
TRP D:257 G:246 94.0 0.369 H -71.7 -45.6 NA NA NA
TRP E:257 M:246 94.0 0.369 H -71.0 -44.6 NA NA NA
TRP F:257 N:246 95.0 0.373 H -70.6 -48.9 NA NA NA
TRP G:257 S:246 90.0 0.353 H -69.1 -49.1 NA NA NA
TRP H:257 T:246 93.0 0.365 H -67.3 -47.5 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 TRP A:248 A:246 87.0 0.341 H -70.1 -41.8 64.0 0.251 0.09 B:P21549:0.09
TRP B:248 C:246 88.0 0.345 H -62.1 -50.0 65.0 0.255 0.09 A:P21549:0.09
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 TRP A:246 A:246 82.0 0.322 H -70.5 -51.1 49.0 0.192 0.13 A:P21549:0.129
 HOH
 3.594
 CH2
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 TRP A:246 A:246 87.0 0.341 H -68.1 -42.6 55.0 0.216 0.125 A:P21549:0.125
 HOH
 3.629
 NE1
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 TRP A:241 A:246 106.0 0.416 H -61.3 -46.6 74.0 0.29 0.126 B:P21549:0.125
 HOH
 2.294
 HE1
 O
TRP B:241 B:246 104.0 0.408 H -65.3 -46.1 71.0 0.278 0.13 A:P21549:0.129
 HOH
 2.064
 HE1
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 TRP A:241 A:246 106.0 0.416 H -64.0 -47.6 74.0 0.29 0.126 B:P21549:0.125
 PLR
HOH
 9.981
2.368
 HZ3
HE1
 H5A1
O
TRP B:241 B:246 105.0 0.412 H -66.4 -45.2 71.0 0.278 0.134 A:P21549:0.133
 HOH
 2.207
 HE1
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 TRP A:246 A:246 88.0 0.345 H -69.8 -44.5 55.0 0.216 0.129 B:P21549:0.129
 BTB
HOH
 2.905
2.810
 NE1
O
 O8
O
TRP B:246 B:246 85.0 0.333 H -69.4 -44.1 56.0 0.22 0.113 A:P21549:0.114
 BTB
GOL
HOH
 3.298
3.388
2.791
 NE1
NE1
O
 O8
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 TRP A:246 A:246 89.0 0.349 H -68.9 -42.1