Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241814597 . G A CCDS2543.1:NM_000030.2:c.752tGg>tAg_NP_000021.1:p.251W>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 TRP A:251 A:251 0.0 0.0 T -72.8 9.4 0.0 0.0 0.0 HOH
 2.876
 O
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 TRP A:251 A:251 1.0 0.004 T -70.6 12.8 1.0 0.004 0.0 HOH
 2.847
 O
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:251 A:251 0.0 0.0 H -67.7 -11.7 0.0 0.0 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:251 A:251 15.0 0.059 T -71.6 1.9 15.0 0.059 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 TRP A:253 A:251 0.0 0.0 T -84.4 4.6 0.0 0.0 0.0 HOH
 2.727
 O
 O
TRP C:253 C:251 0.0 0.0 T -83.3 7.3 0.0 0.0 0.0 BTB
HOH
 7.051
2.707
 N
O
 O8
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 TRP A:251 A:251 1.0 0.004 T -75.7 13.7 1.0 0.004 0.0 HOH
 3.874
 NE1
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 TRP A:253 A:251 1.0 0.004 T -75.5 3.8 1.0 0.004 0.0 BTB
HOH
 8.314
2.641
 N
O
 O4
O
TRP B:253 C:251 0.0 0.0 T -82.4 2.9 0.0 0.0 0.0 BTB
BME
HOH
 6.895
3.294
2.679
 N
NE1
O
 O6
O1
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 TRP A:253 A:251 1.0 0.004 T -77.3 5.7 1.0 0.004 0.0
TRP B:253 B:251 0.0 0.0 T -76.4 5.8 0.0 0.0 0.0
TRP C:253 C:251 1.0 0.004 T -77.5 7.1 NA NA NA
TRP D:253 D:251 1.0 0.004 T -76.8 5.7 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 TRP A:251 A:251 1.0 0.004 T -81.6 15.1 1.0 0.004 0.0 HOH
 2.705
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 TRP A:262 A:251 0.0 0.0 T -82.7 11.2 0.0 0.0 0.0 BTB
HOH
 8.121
2.780
 N
O
 O3
O
TRP B:262 B:251 0.0 0.0 T -80.8 6.7 0.0 0.0 0.0 BTB
HOH
 8.082
2.809
 N
O
 O4
O
TRP C:262 E:251 0.0 0.0 T -84.4 8.5 NA NA NA
TRP D:262 G:251 0.0 0.0 T -83.2 10.4 NA NA NA
TRP E:262 M:251 0.0 0.0 T -78.1 9.4 NA NA NA
TRP F:262 N:251 0.0 0.0 T -85.0 10.5 NA NA NA
TRP G:262 S:251 0.0 0.0 T -81.1 7.7 NA NA NA
TRP H:262 T:251 0.0 0.0 T -79.5 8.9 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 TRP A:253 A:251 2.0 0.008 T -84.3 11.0 2.0 0.008 0.0
TRP B:253 C:251 1.0 0.004 T -86.1 8.3 1.0 0.004 0.0 HOH
 7.731
 O
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 TRP A:251 A:251 0.0 0.0 T -78.1 2.6 0.0 0.0 0.0 HOH
 2.735
 NE1
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 TRP A:251 A:251 1.0 0.004 T -84.5 6.5 1.0 0.004 0.0 HOH
 2.938
 O
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 TRP A:246 A:251 0.0 0.0 T -85.2 11.4 0.0 0.0 0.0 HOH
 2.388
 HE1
 O
TRP B:246 B:251 0.0 0.0 T -83.9 11.2 0.0 0.0 0.0 HOH
 2.346
 HE1
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 TRP A:246 A:251 0.0 0.0 T -86.3 9.3 0.0 0.0 0.0 HOH
 2.351
 HE1
 O
TRP B:246 B:251 0.0 0.0 T -82.6 11.5 0.0 0.0 0.0 HOH
 2.250
 HE1
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 TRP A:251 A:251 1.0 0.004 T -80.9 11.4 1.0 0.004 0.0 BTB
HOH
 8.305
2.738
 N
O
 C1
O
TRP B:251 B:251 1.0 0.004 T -83.6 13.9 1.0 0.004 0.0 SO4
BTB
HOH
 7.021
8.047
2.854
 C
N
O
 O3
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 TRP A:251 A:251 0.0 0.0 T -81.4 2.1