Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241814602 . T A CCDS2543.1:NM_000030.2:c.757Tgt>Agt_NP_000021.1:p.253C>S Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 CYS A:253 A:253 23.0 0.17 -84.6 -13.3 23.0 0.17 0.0 HOH
 3.449
 N
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 CYS A:253 A:253 17.0 0.126 -99.2 16.9 17.0 0.126 0.0 HOH
 3.628
 CA
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:253 A:253 28.0 0.207 -72.7 -40.1 28.0 0.207 0.0 HOH
 7.340
 CB
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 CYS A:253 A:253 38.0 0.281 -75.8 -34.0 38.0 0.281 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 CYS A:255 A:253 28.0 0.207 -93.1 -11.4 28.0 0.207 0.0 HOH
 2.745
 O
 O
CYS C:255 C:253 20.0 0.148 -102.9 -2.1 20.0 0.148 0.0 BTB
HOH
 9.372
3.249
 C
O
 C5
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 CYS A:253 A:253 27.0 0.2 -74.1 -42.7 27.0 0.2 0.0 HOH
 1.885
 N
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 CYS A:255 A:253 22.0 0.163 -104.2 -6.0 22.0 0.163 0.0 BTB
HOH
 8.113
3.396
 C
N
 O1
O
CYS B:255 C:253 23.0 0.17 -103.2 -3.2 23.0 0.17 0.0 BTB
HOH
 7.370
2.569
 C
O
 O8
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 CYS A:255 A:253 24.0 0.178 -89.6 -3.6 24.0 0.178 0.0
CYS B:255 B:253 25.0 0.185 -88.8 -8.0 25.0 0.185 0.0
CYS C:255 C:253 24.0 0.178 -90.0 -4.4 NA NA NA
CYS D:255 D:253 25.0 0.185 -88.3 -4.3 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 CYS A:253 A:253 18.0 0.133 -99.3 -8.3 18.0 0.133 0.0 HOH
 2.591
 O
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 CYS A:264 A:253 21.0 0.156 -88.9 -11.1 21.0 0.156 0.0 BTB
HOH
 7.958
2.884
 C
O
 O4
O
CYS B:264 B:253 19.0 0.141 -87.8 -11.3 19.0 0.141 0.0 BTB
HOH
 8.075
2.761
 C
O
 O1
O
CYS C:264 E:253 21.0 0.156 -90.5 -12.4 NA NA NA
CYS D:264 G:253 19.0 0.141 -90.9 -16.0 NA NA NA
CYS E:264 M:253 19.0 0.141 -92.4 -8.9 NA NA NA
CYS F:264 N:253 19.0 0.141 -93.2 -5.2 NA NA NA
CYS G:264 S:253 20.0 0.148 -93.0 -6.0 NA NA NA
CYS H:264 T:253 20.0 0.148 -87.3 -10.9 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 CYS A:255 A:253 23.0 0.17 -97.8 -11.0 23.0 0.17 0.0
CYS B:255 C:253 22.0 0.163 -99.6 -9.8 22.0 0.163 0.0 HOH
 6.774
 CB
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 CYS A:253 A:253 19.0 0.141 -89.1 3.3 19.0 0.141 0.0 HOH
 3.360
 SG
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 CYS A:253 A:253 21.0 0.156 -86.2 -2.3 21.0 0.156 0.0 HOH
 2.341
 O
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 CYS A:248 A:253 19.0 0.141 -97.5 -12.6 19.0 0.141 0.0 HOH
 2.723
 O
 O
CYS B:248 B:253 25.0 0.185 -99.8 -3.7 25.0 0.185 0.0 HOH
 2.877
 HB3
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 CYS A:248 A:253 19.0 0.141 -98.5 -10.1 19.0 0.141 0.0 HOH
 2.760
 O
 O
CYS B:248 B:253 23.0 0.17 -101.4 -2.4 23.0 0.17 0.0 HOH
 2.837
 HB3
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 CYS A:253 A:253 27.0 0.2 -96.6 -9.3 27.0 0.2 0.0 BTB
HOH
 8.046
2.669
 C
O
 O4
O
CYS B:253 B:253 28.0 0.207 -91.0 -6.9 28.0 0.207 0.0 SO4
BTB
HOH
 7.666
8.068
2.980
 N
C
O
 O3
O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 CYS A:253 A:253 13.0 0.096 -100.8 0.4