Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 241815354 | . | A | C | CCDS2543.1:NM_000030.2:c.779tAc>tCc_NP_000021.1:p.260Y>S | Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1h0c | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2003-06-12 | TYR | A:260 | A:260 | 130.0 | 0.565 | -58.1 | 119.8 | 35.0 | 0.152 | 0.413 |
A:P21549:0.413 |
PLP AOA GOL HOH |
2.921 3.809 6.814 3.558 |
OH OH O CD1 |
O1P C1 C3 O |
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| 5og0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-09-27 | TYR | A:260 | A:260 | 137.0 | 0.596 | -56.4 | 117.0 | 37.0 | 0.161 | 0.435 |
A:P21549:0.435 |
PLP HOH |
2.555 5.162 |
OH CZ |
O3P O |
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| 6rv0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | TYR | A:260 | A:260 | 137.0 | 0.596 | -59.4 | 112.5 | 43.0 | 0.187 | 0.409 |
A:P21549:0.409 |
PMP HOH |
2.213 7.965 |
OH OH |
O1P O |
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| 6rv1 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | TYR | A:260 | A:260 | 132.0 | 0.574 | -50.8 | 121.9 | 63.0 | 0.274 | 0.3 |
A:P21549:0.3 |
PLP |
2.121 |
OH |
O3P |
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| 3r9a | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2011-05-11 | TYR | A:262 | A:260 | 133.0 | 0.578 | -55.2 | 129.5 | 26.0 | 0.113 | 0.465 |
C:P21549:0.465 |
HOH |
3.101 |
OH |
O |
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| TYR | C:262 | C:260 | 133.0 | 0.578 | -59.0 | 127.2 | 31.0 | 0.135 | 0.443 |
A:P21549:0.443 |
BTB HOH |
4.896 2.557 |
O O |
O8 O |
|||||||||
| 5ofy | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-27 | TYR | A:260 | A:260 | 128.0 | 0.557 | -52.7 | 133.3 | 34.0 | 0.148 | 0.409 |
A:P21549:0.409 |
PLP DIO HOH |
2.332 3.870 3.671 |
OH CD1 CE1 |
O1P C1 O |
||
| 4kyo | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2014-11-19 | TYR | A:262 | A:260 | 134.0 | 0.583 | -58.3 | 129.5 | 37.0 | 0.161 | 0.422 |
B:P21549:0.422 |
SO4 BTB BME HOH |
2.613 6.099 5.804 2.968 |
OH O CB N |
O2 O4 O1 O |
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| TYR | B:262 | C:260 | 134.0 | 0.583 | -65.0 | 129.9 | 39.0 | 0.17 | 0.413 |
A:P21549:0.413 |
SO4 BME BTB HOH |
2.602 7.162 4.382 2.935 |
OH CB O N |
O1 O1 O6 O |
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| 4i8a | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:262 | A:260 | 141.0 | 0.613 | -51.4 | 129.9 | 26.0 | 0.113 | 0.5 |
B:P21549:0.5 |
GOL |
3.591 |
CD1 |
C1 |
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| TYR | B:262 | B:260 | 138.0 | 0.6 | -52.6 | 129.9 | 27.0 | 0.117 | 0.483 |
A:P21549:0.483 |
GOL GOL |
3.724 5.418 |
CD1 O |
C2 O3 |
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| TYR | C:262 | C:260 | 142.0 | 0.617 | -51.0 | 130.0 | NA | NA | NA | ||||||||||||||
| TYR | D:262 | D:260 | 138.0 | 0.6 | -50.9 | 129.1 | NA | NA | NA | ||||||||||||||
| 1j04 | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2003-11-11 | TYR | A:260 | A:260 | 132.0 | 0.574 | -77.2 | 128.6 | 132.0 | 0.574 | 0.0 |
HOH |
3.709 |
CD1 |
O |
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| 5luc | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-20 | TYR | A:271 | A:260 | 136.0 | 0.591 | -54.5 | 124.3 | 40.0 | 0.174 | 0.417 |
B:P21549:0.417 |
BTB PLP HOH |
6.176 2.678 2.865 |
O OH N |
O3 O2P O |
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| TYR | B:271 | B:260 | 132.0 | 0.574 | -57.2 | 130.2 | 36.0 | 0.157 | 0.417 |
A:P21549:0.417 |
PLP BTB HOH |
2.621 6.107 2.723 |
OH O O |
O1P O4 O |
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| TYR | C:271 | E:260 | 134.0 | 0.583 | -60.0 | 127.3 | NA | NA | NA | ||||||||||||||
| TYR | D:271 | G:260 | 130.0 | 0.565 | -56.8 | 131.0 | NA | NA | NA | ||||||||||||||
| TYR | E:271 | M:260 | 137.0 | 0.596 | -58.5 | 129.5 | NA | NA | NA | ||||||||||||||
| TYR | F:271 | N:260 | 138.0 | 0.6 | -55.6 | 129.9 | NA | NA | NA | ||||||||||||||
| TYR | G:271 | S:260 | 134.0 | 0.583 | -63.3 | 129.1 | NA | NA | NA | ||||||||||||||
| TYR | H:271 | T:260 | 135.0 | 0.587 | -57.2 | 130.6 | NA | NA | NA | ||||||||||||||
| 4kxk | 1 | P21549 | 99.49 | 0.0 |
X-RAY |
2014-11-19 | TYR | A:262 | A:260 | 125.0 | 0.543 | -52.5 | 130.0 | 35.0 | 0.152 | 0.391 |
B:P21549:0.391 |
SO4 HOH |
2.246 5.852 |
OH OH |
O4 O |
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| TYR | B:262 | C:260 | 124.0 | 0.539 | -60.5 | 125.8 | 35.0 | 0.152 | 0.387 |
A:P21549:0.387 |
SO4 BME HOH |
2.481 4.226 6.576 |
OH CE1 CB |
O2 S2 O |
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| 4cbr | 1 | P21549 | 99.23 | 0.0 |
X-RAY |
2014-07-09 | TYR | A:260 | A:260 | 123.0 | 0.535 | -62.6 | 137.9 | 26.0 | 0.113 | 0.422 |
A:P21549:0.422 |
PLP GOL HOH |
2.561 3.579 3.574 |
OH OH CD1 |
O2P C1 O |
||
| 4cbs | 1 | P21549 | 98.72 | 0.0 |
X-RAY |
2014-07-09 | TYR | A:260 | A:260 | 117.0 | 0.509 | -57.1 | 136.4 | 25.0 | 0.109 | 0.4 |
A:P21549:0.4 |
PLP HOH |
2.561 3.662 |
OH C |
O1P O |
||
| 5f9s | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2016-12-21 | TYR | A:255 | A:260 | 130.0 | 0.565 | -58.9 | 128.1 | 32.0 | 0.139 | 0.426 |
B:P21549:0.426 |
PLP HOH |
1.817 2.588 |
HH O |
O2P O |
||
| TYR | B:255 | B:260 | 138.0 | 0.6 | -64.0 | 126.0 | 37.0 | 0.161 | 0.439 |
A:P21549:0.439 |
PLP HOH |
1.838 1.971 |
HH H |
O1P O |
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| 5hhy | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | TYR | A:255 | A:260 | 130.0 | 0.565 | -60.3 | 129.1 | 35.0 | 0.152 | 0.413 |
B:P21549:0.413 |
PLR HOH |
1.920 2.592 |
HH O |
O3P O |
||
| TYR | B:255 | B:260 | 136.0 | 0.591 | -60.9 | 124.9 | 40.0 | 0.174 | 0.417 |
A:P21549:0.417 |
PLR HOH |
1.831 1.904 |
HH H |
O1P O |
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| 2yob | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-10-30 | TYR | A:260 | A:260 | 130.0 | 0.565 | -57.6 | 129.2 | 35.0 | 0.152 | 0.413 |
B:P21549:0.413 |
BTB PLP HOH |
5.327 2.584 2.852 |
O OH N |
O1 O2P O |
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| TYR | B:260 | B:260 | 129.0 | 0.561 | -58.2 | 126.8 | 31.0 | 0.135 | 0.426 |
A:P21549:0.426 |
PLP BTB GOL HOH |
2.704 5.837 9.604 2.848 |
OH O O N |
O1P O1 O3 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p21549-f1 | 1 | P21549 | 100.0 | 0.0 | TYR | A:260 | A:260 | 141.0 | 0.613 | -59.6 | 128.3 | ||