Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241815358 . T A CCDS2543.1:NM_000030.2:c.783caT>caA_NP_000021.1:p.261H>Q Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 HIS A:261 A:261 10.0 0.051 -110.8 -73.0 0.0 0.0 0.051 A:P21549:0.051
 PLP
AOA
GOL
HOH
 5.298
7.238
7.902
2.710
 O
O
O
N
 O3P
C1
O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 HIS A:261 A:261 10.0 0.051 -104.6 -66.7 0.0 0.0 0.051 A:P21549:0.051
 PLP
HOH
 5.424
4.068
 O
CE1
 O3P
O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:261 A:261 11.0 0.056 -96.6 -84.9 0.0 0.0 0.056 A:P21549:0.056
 PMP
 4.958
 O
 O1P
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 HIS A:261 A:261 9.0 0.046 -108.0 -76.1 0.0 0.0 0.046 A:P21549:0.046
 PLP
 4.911
 O
 O3P
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 HIS A:263 A:261 10.0 0.051 -121.6 -66.6 0.0 0.0 0.051 C:P21549:0.051
 HOH
 2.784
 O
 O
HIS C:263 C:261 10.0 0.051 -118.3 -62.8 1.0 0.005 0.046 A:P21549:0.046
 BTB
HOH
 4.277
2.784
 CB
N
 O8
O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 HIS A:261 A:261 10.0 0.051 -123.6 -74.6 0.0 0.0 0.051 A:P21549:0.051
 PLP
DIO
HOH
 5.072
7.246
6.171
 O
N
ND1
 O1P
C1
O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 HIS A:263 A:261 8.0 0.041 -124.1 -62.6 3.0 0.015 0.026 B:P21549:0.026
 SO4
BTB
BME
HOH
 5.184
6.324
9.113
2.793
 O
CB
N
O
 O3
O4
O1
O
HIS B:263 C:261 8.0 0.041 -124.1 -63.2 2.0 0.01 0.031 A:P21549:0.031
 SO4
BTB
BME
HOH
 5.014
4.059
4.307
2.710
 O
CB
CE1
N
 O3
O6
S2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 HIS A:263 A:261 10.0 0.051 -124.2 -54.5 0.0 0.0 0.051 B:P21549:0.051
 GOL
 6.837
 N
 O1
HIS B:263 B:261 8.0 0.041 -125.3 -55.0 0.0 0.0 0.041 A:P21549:0.041
 GOL
GOL
 7.112
7.542
 N
N
 C2
O3
HIS C:263 C:261 10.0 0.051 -125.8 -54.7 NA NA NA
HIS D:263 D:261 10.0 0.051 -123.5 -53.0 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 HIS A:261 A:261 12.0 0.062 -116.0 -77.2 12.0 0.062 0.0 HOH
 3.024
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 HIS A:272 A:261 9.0 0.046 -113.6 -72.9 0.0 0.0 0.046 B:P21549:0.046
 BTB
PLP
HOH
 5.966
5.274
2.840
 CB
O
N
 O3
O2P
O
HIS B:272 B:261 10.0 0.051 -121.5 -71.4 1.0 0.005 0.046 A:P21549:0.046
 PLP
BTB
HOH
 5.339
5.909
2.846
 O
CB
N
 O2P
O4
O
HIS C:272 E:261 10.0 0.051 -117.9 -71.6 NA NA NA
HIS D:272 G:261 10.0 0.051 -122.3 -71.1 NA NA NA
HIS E:272 M:261 9.0 0.046 -120.8 -72.2 NA NA NA
HIS F:272 N:261 9.0 0.046 -119.0 -68.0 NA NA NA
HIS G:272 S:261 10.0 0.051 -119.1 -70.9 NA NA NA
HIS H:272 T:261 9.0 0.046 -122.1 -72.9 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 HIS A:263 A:261 11.0 0.056 -130.3 -67.5 4.0 0.021 0.035 B:P21549:0.036
 SO4
HOH
 4.780
9.392
 O
O
 O2
O
HIS B:263 C:261 11.0 0.056 -118.7 -65.6 3.0 0.015 0.041 A:P21549:0.041
 SO4
BME
HOH
 4.771
7.752
9.937
 O
O
N
 O2
S2
O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 HIS A:261 A:261 10.0 0.051 -126.1 -69.0 0.0 0.0 0.051 A:P21549:0.051
 PLP
GOL
HOH
 5.156
7.109
2.794
 O
N
N
 O2P
O3
O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 HIS A:261 A:261 10.0 0.051 -126.8 -65.8 0.0 0.0 0.051 A:P21549:0.051
 PLP
HOH
 5.462
2.766
 O
N
 O1P
O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 HIS A:256 A:261 8.0 0.041 -114.6 -70.3 0.0 0.0 0.041 B:P21549:0.041
 PLP
HOH
 5.376
2.020
 O
H
 O2P
O
HIS B:256 B:261 10.0 0.051 -115.5 -68.3 0.0 0.0 0.051 A:P21549:0.051
 PLP
HOH
 5.317
1.836
 O
H
 O2P
O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 HIS A:256 A:261 9.0 0.046 -114.1 -66.4 0.0 0.0 0.046 B:P21549:0.046
 PLR
HOH
 5.412
2.016
 O
H
 O2P
O
HIS B:256 B:261 10.0 0.051 -116.3 -68.4 0.0 0.0 0.051 A:P21549:0.051
 PLR
HOH
 5.250
1.906
 O
H
 O2P
O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 HIS A:261 A:261 10.0 0.051 -118.3 -69.9 0.0 0.0 0.051 B:P21549:0.051
 BTB
PLP
HOH
 6.046
5.347
2.659
 CB
O
N
 O1
O2P
O
HIS B:261 B:261 9.0 0.046 -116.0 -67.2 0.0 0.0 0.046 A:P21549:0.046
 PLP
BTB
GOL
HOH
 5.271
5.788
8.525
2.836
 O
CB
CD2
N
 O2P
O1
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 HIS A:261 A:261 11.0 0.056 -118.7 -62.9