Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 241815371 | . | G | A | CCDS2543.1:NM_000030.2:c.796Gtc>Atc_NP_000021.1:p.266V>I | Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1h0c | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2003-06-12 | VAL | A:266 | A:266 | 6.0 | 0.039 | H | -37.9 | -58.1 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLP AOA HOH |
9.712 9.849 3.473 |
CG2 CG2 N |
O1P N1 O |
|
| 5og0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-09-27 | VAL | A:266 | A:266 | 6.0 | 0.039 | H | -45.4 | -55.1 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLP HOH |
9.705 3.312 |
N N |
O2P O |
|
| 6rv0 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | VAL | A:266 | A:266 | 4.0 | 0.026 | H | -45.6 | -53.3 | 0.0 | 0.0 | 0.026 |
A:P21549:0.026 |
PMP HOH |
9.689 7.940 |
N CB |
O2P O |
|
| 6rv1 | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | VAL | A:266 | A:266 | 4.0 | 0.026 | H | -42.4 | -50.1 | 0.0 | 0.0 | 0.026 |
A:P21549:0.026 |
PLP |
9.707 |
N |
O2P |
|
| 3r9a | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2011-05-11 | VAL | A:268 | A:266 | 6.0 | 0.039 | H | -49.2 | -47.6 | 0.0 | 0.0 | 0.039 |
C:P21549:0.039 |
HOH |
3.573 |
N |
O |
|
| VAL | C:268 | C:266 | 8.0 | 0.052 | H | -37.0 | -56.6 | 0.0 | 0.0 | 0.052 |
A:P21549:0.052 |
HOH |
3.492 |
N |
O |
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| 5ofy | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-27 | VAL | A:266 | A:266 | 6.0 | 0.039 | H | -48.3 | -54.4 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLP DIO HOH |
9.428 9.403 3.460 |
N CG2 N |
O3P O1 O |
|
| 4kyo | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2014-11-19 | VAL | A:268 | A:266 | 7.0 | 0.045 | H | -41.6 | -55.3 | 0.0 | 0.0 | 0.045 |
B:P21549:0.045 |
SO4 BME HOH |
9.606 3.218 5.910 |
N N CG2 |
O4 O1 O |
|
| VAL | B:268 | C:266 | 6.0 | 0.039 | H | -38.9 | -51.6 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
SO4 BME BME HOH |
9.776 7.426 9.392 3.557 |
N C N N |
O2 S2 O1 O |
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| 4i8a | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-05-01 | VAL | A:268 | A:266 | 6.0 | 0.039 | H | -32.3 | -57.3 | 0.0 | 0.0 | 0.039 |
B:P21549:0.039 |
GOL |
9.874 |
CG2 |
C1 |
|
| VAL | B:268 | B:266 | 6.0 | 0.039 | H | -34.7 | -56.8 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
GOL |
8.721 |
CG2 |
O3 |
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| VAL | C:268 | C:266 | 7.0 | 0.045 | H | -30.5 | -57.9 | NA | NA | NA | |||||||||||||
| VAL | D:268 | D:266 | 6.0 | 0.039 | H | -32.9 | -58.9 | NA | NA | NA | |||||||||||||
| 1j04 | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2003-11-11 | VAL | A:266 | A:266 | 5.0 | 0.032 | H | -44.0 | -60.4 | 5.0 | 0.032 | 0.0 |
HOH |
3.450 |
N |
O |
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| 5luc | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2017-09-20 | VAL | A:277 | A:266 | 5.0 | 0.032 | H | -43.4 | -57.3 | 0.0 | 0.0 | 0.032 |
B:P21549:0.032 |
PLP HOH |
9.720 3.391 |
N N |
O1P O |
|
| VAL | B:277 | B:266 | 4.0 | 0.026 | H | -40.7 | -54.4 | 0.0 | 0.0 | 0.026 |
A:P21549:0.026 |
PLP HOH |
9.742 3.254 |
N N |
O3P O |
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| VAL | C:277 | E:266 | 3.0 | 0.019 | H | -45.3 | -52.3 | NA | NA | NA | |||||||||||||
| VAL | D:277 | G:266 | 4.0 | 0.026 | H | -44.2 | -52.1 | NA | NA | NA | |||||||||||||
| VAL | E:277 | M:266 | 5.0 | 0.032 | H | -40.4 | -58.9 | NA | NA | NA | |||||||||||||
| VAL | F:277 | N:266 | 5.0 | 0.032 | H | -41.5 | -56.7 | NA | NA | NA | |||||||||||||
| VAL | G:277 | S:266 | 6.0 | 0.039 | H | -41.6 | -59.9 | NA | NA | NA | |||||||||||||
| VAL | H:277 | T:266 | 5.0 | 0.032 | H | -43.0 | -55.6 | NA | NA | NA | |||||||||||||
| 4kxk | 1 | P21549 | 99.49 | 0.0 |
X-RAY |
2014-11-19 | VAL | A:268 | A:266 | 5.0 | 0.032 | H | -46.5 | -47.3 | 0.0 | 0.0 | 0.032 |
B:P21549:0.032 |
SO4 |
9.506 |
N |
O1 |
|
| VAL | B:268 | C:266 | 6.0 | 0.039 | H | -47.7 | -46.0 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
SO4 |
9.656 |
N |
O1 |
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| 4cbr | 1 | P21549 | 99.23 | 0.0 |
X-RAY |
2014-07-09 | VAL | A:266 | A:266 | 6.0 | 0.039 | H | -36.8 | -51.1 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLP HOH |
9.909 3.470 |
N N |
O3P O |
|
| 4cbs | 1 | P21549 | 98.72 | 0.0 |
X-RAY |
2014-07-09 | VAL | A:266 | A:266 | 4.0 | 0.026 | H | -33.1 | -53.9 | 0.0 | 0.0 | 0.026 |
A:P21549:0.026 |
PLP HOH |
9.746 6.083 |
CG2 CG2 |
O1P O |
|
| 5f9s | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2016-12-21 | VAL | A:261 | A:266 | 4.0 | 0.026 | H | -45.9 | -52.7 | 0.0 | 0.0 | 0.026 |
B:P21549:0.026 |
PLP HOH |
8.936 3.297 |
H N |
O1P O |
|
| VAL | B:261 | B:266 | 6.0 | 0.039 | H | -41.8 | -54.3 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLP HOH |
8.851 3.410 |
H N |
O3P O |
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| 5hhy | 1 | P21549 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:261 | A:266 | 3.0 | 0.019 | H | -47.9 | -50.6 | 0.0 | 0.0 | 0.019 |
B:P21549:0.019 |
PLR HOH |
8.991 3.326 |
H N |
O1P O |
|
| VAL | B:261 | B:266 | 6.0 | 0.039 | H | -42.4 | -54.6 | 0.0 | 0.0 | 0.039 |
A:P21549:0.039 |
PLR HOH |
8.940 3.375 |
H N |
O3P O |
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| 2yob | 1 | P21549 | 99.74 | 0.0 |
X-RAY |
2013-10-30 | VAL | A:266 | A:266 | 7.0 | 0.045 | H | -44.0 | -51.3 | 0.0 | 0.0 | 0.045 |
B:P21549:0.045 |
PLP HOH |
9.494 3.392 |
N N |
O1P O |
|
| VAL | B:266 | B:266 | 8.0 | 0.052 | H | -42.8 | -55.4 | 0.0 | 0.0 | 0.052 |
A:P21549:0.052 |
PLP HOH |
9.593 3.304 |
N N |
O3P O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p21549-f1 | 1 | P21549 | 100.0 | 0.0 | VAL | A:266 | A:266 | 4.0 | 0.026 | H | -42.7 | -54.3 | |