Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241816970 . G A CCDS2543.1:NM_000030.2:c.863tGg>tAg_NP_000021.1:p.288W>* Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 TRP A:288 A:288 31.0 0.122 H -65.3 -37.6 26.0 0.102 0.02 A:P21549:0.02
 GOL
HOH
 7.743
2.858
 O
NE1
 O3
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 TRP A:288 A:288 21.0 0.082 H -66.5 -36.6 17.0 0.067 0.015 A:P21549:0.016
 HOH
 3.701
 CZ2
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:288 A:288 15.0 0.059 H -71.6 -37.7 12.0 0.047 0.012 A:P21549:0.012
 HOH
 3.550
 CZ2
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 TRP A:288 A:288 32.0 0.125 H -69.2 -42.4 32.0 0.125 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 TRP A:290 A:288 20.0 0.078 H -61.6 -43.1 16.0 0.063 0.015 C:P21549:0.016
 HOH
 2.620
 O
 O
TRP C:290 C:288 17.0 0.067 H -66.5 -33.9 14.0 0.055 0.012 A:P21549:0.012
 HOH
 2.694
 NE1
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 TRP A:288 A:288 11.0 0.043 H -63.8 -36.7 7.0 0.027 0.016 A:P21549:0.016
 HOH
 3.552
 CZ2
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 TRP A:290 A:288 16.0 0.063 H -56.3 -42.4 14.0 0.055 0.008 B:P21549:0.008
 BME
HOH
 7.890
2.731
 CZ3
O
 S2
O
TRP B:290 C:288 12.0 0.047 H -59.4 -39.0 10.0 0.039 0.008 A:P21549:0.008
 HOH
 2.666
 O
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 TRP A:290 A:288 35.0 0.137 H -56.3 -48.4 30.0 0.118 0.019 B:P21549:0.02
TRP B:290 B:288 27.0 0.106 H -55.8 -49.4 23.0 0.09 0.016 A:P21549:0.016
TRP C:290 C:288 33.0 0.129 H -55.6 -48.7 NA NA NA
TRP D:290 D:288 29.0 0.114 H -57.1 -48.6 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 TRP A:288 A:288 14.0 0.055 H -68.2 -37.3 14.0 0.055 0.0 GOL
HOH
 8.488
2.967
 O
NE1
 O3
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 TRP A:299 A:288 17.0 0.067 H -57.3 -46.0 12.0 0.047 0.02 B:P21549:0.02
 HOH
 2.935
 O
 O
TRP B:299 B:288 18.0 0.071 H -58.5 -41.6 14.0 0.055 0.016 A:P21549:0.016
 HOH
 2.897
 NE1
 O
TRP C:299 E:288 15.0 0.059 H -60.1 -43.4 NA NA NA
TRP D:299 G:288 18.0 0.071 H -57.9 -43.8 NA NA NA
TRP E:299 M:288 17.0 0.067 H -55.4 -45.4 NA NA NA
TRP F:299 N:288 13.0 0.051 H -58.7 -41.4 NA NA NA
TRP G:299 S:288 16.0 0.063 H -54.8 -45.3 NA NA NA
TRP H:299 T:288 18.0 0.071 H -59.1 -42.7 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 TRP A:290 A:288 20.0 0.078 H -62.6 -47.0 17.0 0.067 0.011 B:P21549:0.012
 HOH
 3.871
 C
 O
TRP B:290 C:288 16.0 0.063 H -58.9 -51.9 13.0 0.051 0.012 A:P21549:0.012
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 TRP A:288 A:288 16.0 0.063 H -56.8 -41.9 12.0 0.047 0.016 A:P21549:0.016
 HOH
 3.355
 CZ2
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 TRP A:288 A:288 14.0 0.055 H -63.5 -41.9 5.0 0.02 0.035 A:P21549:0.035
 HOH
 3.785
 CZ2
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 TRP A:283 A:288 15.0 0.059 H -56.1 -43.8 13.0 0.051 0.008 B:P21549:0.008
 HOH
 2.269
 HE1
 O
TRP B:283 B:288 16.0 0.063 H -56.9 -43.3 13.0 0.051 0.012 A:P21549:0.012
 HOH
 2.234
 HE1
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 TRP A:283 A:288 16.0 0.063 H -56.8 -41.7 13.0 0.051 0.012 B:P21549:0.012
 HOH
 2.343
 HE1
 O
TRP B:283 B:288 17.0 0.067 H -58.8 -43.0 13.0 0.051 0.016 A:P21549:0.016
 HOH
 2.272
 HE1
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 TRP A:288 A:288 13.0 0.051 H -60.6 -43.8 9.0 0.035 0.016 B:P21549:0.016
 HOH
 2.995
 NE1
 O
TRP B:288 B:288 16.0 0.063 H -54.0 -42.3 13.0 0.051 0.012 A:P21549:0.012
 HOH
 2.834
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 TRP A:288 A:288 17.0 0.067 H -61.0 -41.0