Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241817515 . T A CCDS2543.1:NM_000030.2:c.1019aTa>aAa_NP_000021.1:p.340I>K Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ILE A:340 A:340 46.0 0.263 H -73.2 -31.7 46.0 0.263 0.0 GOL
GOL
HOH
 4.456
8.351
3.372
 CG2
O
N
 O3
O2
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ILE A:340 A:340 46.0 0.263 H -78.2 -38.9 46.0 0.263 0.0 HOH
 3.363
 CB
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ILE A:340 A:340 40.0 0.229 H -59.2 -46.2 40.0 0.229 0.0 HOH
 3.014
 CB
 O
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ILE A:340 A:340 67.0 0.383 H -55.6 -49.7 67.0 0.383 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ILE A:342 A:340 41.0 0.234 H -78.4 -42.1 41.0 0.234 0.0 HOH
 3.408
 CB
 O
ILE C:342 C:340 42.0 0.24 H -76.2 -45.4 42.0 0.24 0.0 HOH
 2.576
 O
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ILE A:340 A:340 43.0 0.246 H -71.5 -46.8 43.0 0.246 0.0 HOH
 8.637
 CD1
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ILE A:342 A:340 42.0 0.24 H -75.9 -43.7 42.0 0.24 0.0 BME
HOH
 7.981
3.521
 CG2
N
 S2
O
ILE B:342 C:340 45.0 0.257 H -77.7 -41.0 45.0 0.257 0.0 BME
HOH
 9.366
2.752
 CG2
O
 S2
O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ILE A:342 A:340 47.0 0.269 H -73.3 -40.1 47.0 0.269 0.0 GOL
 4.696
 CG1
 O1
ILE B:342 B:340 46.0 0.263 H -72.9 -39.9 46.0 0.263 0.0
ILE C:342 C:340 46.0 0.263 H -71.9 -40.3 NA NA NA
ILE D:342 D:340 47.0 0.269 H -73.8 -39.9 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ILE A:340 A:340 47.0 0.269 H -73.3 -41.7 47.0 0.269 0.0 GOL
HOH
 7.806
3.999
 O
CD1
 C2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ILE A:351 A:340 44.0 0.251 H -73.6 -37.8 44.0 0.251 0.0 HOH
 2.977
 O
 O
ILE B:351 B:340 45.0 0.257 H -74.8 -39.1 45.0 0.257 0.0 HOH
 3.046
 O
 O
ILE C:351 E:340 45.0 0.257 H -71.3 -39.3 NA NA NA
ILE D:351 G:340 45.0 0.257 H -77.0 -36.0 NA NA NA
ILE E:351 M:340 46.0 0.263 H -80.2 -40.1 NA NA NA
ILE F:351 N:340 43.0 0.246 H -75.5 -35.8 NA NA NA
ILE G:351 S:340 45.0 0.257 H -77.0 -41.8 NA NA NA
ILE H:351 T:340 47.0 0.269 H -80.0 -36.0 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ILE A:342 A:340 42.0 0.24 H -70.1 -43.4 42.0 0.24 0.0
ILE B:342 C:340 41.0 0.234 H -72.5 -38.6 41.0 0.234 0.0 HOH
 4.636
 CG1
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 MET A:340 A:340 47.0 0.254 H -66.5 -51.6 44.0 0.238 0.016 A:P21549:0.016
 HOH
 3.069
 N
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 MET A:340 A:340 43.0 0.232 H -75.4 -47.8 42.0 0.227 0.005 A:P21549:0.005
 HOH
 3.526
 CB
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ILE A:335 A:340 43.0 0.246 H -75.2 -39.6 36.0 0.206 0.04 B:P21549:0.04
 HOH
 2.770
 HB
 O
ILE B:335 B:340 38.0 0.217 H -75.8 -41.5 38.0 0.217 0.0 HOH
 2.609
 HB
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ILE A:335 A:340 45.0 0.257 H -74.9 -42.4 32.0 0.183 0.074 B:P21549:0.074
 HOH
 2.821
 HB
 O
ILE B:335 B:340 40.0 0.229 H -77.5 -39.8 40.0 0.229 0.0 HOH
 2.536
 O
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 MET A:340 A:340 45.0 0.243 H -75.6 -50.3 43.0 0.232 0.011 B:P21549:0.011
 GOL
HOH
 3.342
3.305
 CB
CE
 O2
O
MET B:340 B:340 44.0 0.238 H -72.7 -49.7 44.0 0.238 0.0 GOL
HOH
 3.500
3.537
 CE
CB
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ILE A:340 A:340 39.0 0.223 H -73.2 -42.5