Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241818179 . G A CCDS2543.1:NM_000030.2:c.1120Gac>Aac_NP_000021.1:p.374D>N Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ASP A:374 A:374 50.0 0.333 H -65.0 -52.1 50.0 0.333 0.0 GOL
GOL
HOH
 9.744
8.283
2.774
 C
OD1
OD1
 O2
O1
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ASP A:374 A:374 54.0 0.36 H -59.0 -53.2 54.0 0.36 0.0 HOH
 2.690
 OD2
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:374 A:374 59.0 0.393 H -50.1 -63.5 59.0 0.393 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ASP A:374 A:374 56.0 0.373 H -41.6 -62.4 56.0 0.373 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ASP A:376 A:374 60.0 0.4 H -57.0 -42.8 60.0 0.4 0.0 HOH
 2.746
 OD2
 O
ASP C:376 C:374 35.0 0.233 H -60.6 -42.7 35.0 0.233 0.0 HOH
 4.929
 O
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ASP A:374 A:374 42.0 0.28 H -48.8 -62.8 42.0 0.28 0.0 HOH
 9.234
 C
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ASP A:376 A:374 50.0 0.333 H -61.0 -43.8 50.0 0.333 0.0 BME
HOH
 6.976
5.032
 OD1
O
 S2
O
ASP B:376 C:374 61.0 0.407 H -63.6 -43.3 61.0 0.407 0.0 HOH
 2.846
 OD2
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ASP A:376 A:374 62.0 0.413 H -68.0 -47.9 62.0 0.413 0.0
ASP B:376 B:374 49.0 0.327 H -66.3 -48.4 49.0 0.327 0.0
ASP C:376 C:374 59.0 0.393 H -65.9 -48.0 NA NA NA
ASP D:376 D:374 49.0 0.327 H -66.9 -48.3 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ASP A:374 A:374 47.0 0.313 H -72.1 -53.0 47.0 0.313 0.0 GOL
GOL
HOH
 9.152
7.571
2.422
 C
OD1
OD1
 O2
O1
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ASP A:385 A:374 49.0 0.327 H -65.7 -39.1 49.0 0.327 0.0 HOH
 2.787
 OD2
 O
ASP B:385 B:374 49.0 0.327 H -60.1 -41.8 49.0 0.327 0.0 HOH
 2.846
 OD2
 O
ASP C:385 E:374 46.0 0.307 H -59.7 -42.6 NA NA NA
ASP D:385 G:374 48.0 0.32 H -62.1 -42.8 NA NA NA
ASP E:385 M:374 49.0 0.327 H -62.4 -41.0 NA NA NA
ASP F:385 N:374 49.0 0.327 H -60.4 -41.2 NA NA NA
ASP G:385 S:374 49.0 0.327 H -61.3 -43.2 NA NA NA
ASP H:385 T:374 51.0 0.34 H -62.1 -37.2 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ASP A:376 A:374 50.0 0.333 H -62.8 -45.2 50.0 0.333 0.0
ASP B:376 C:374 52.0 0.347 H -67.9 -41.0 52.0 0.347 0.0 HOH
 6.789
 OD2
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ASP A:374 A:374 44.0 0.293 H -63.4 -52.4 44.0 0.293 0.0 HOH
 3.105
 OD2
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ASP A:374 A:374 44.0 0.293 H -72.6 -40.6 44.0 0.293 0.0 HOH
 3.611
 CB
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ASP A:369 A:374 61.0 0.407 H -59.2 -41.6 61.0 0.407 0.0 HOH
 2.725
 O
 O
ASP B:369 B:374 42.0 0.28 H -65.1 -43.2 42.0 0.28 0.0 HOH
 2.562
 OD2
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ASP A:369 A:374 53.0 0.353 H -55.8 -42.6 53.0 0.353 0.0 HOH
 2.764
 OD2
 O
ASP B:369 B:374 42.0 0.28 H -65.6 -41.8 42.0 0.28 0.0 HOH
 2.625
 OD2
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ASP A:374 A:374 41.0 0.273 H -62.7 -42.5 41.0 0.273 0.0 HOH
 4.706
 OD1
 O
ASP B:374 B:374 43.0 0.287 H -58.8 -44.6 43.0 0.287 0.0 HOH
 3.213
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ASP A:374 A:374 43.0 0.287 H -63.2 -47.2