Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241818182 . C A CCDS2543.1:NM_000030.2:c.1123Cgc>Agc_NP_000021.1:p.375R>S Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 ARG A:375 A:375 156.0 0.693 H -58.1 -49.5 156.0 0.693 0.0 GOL
HOH
 4.246
2.668
 NH1
NH1
 O2
O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 ARG A:375 A:375 161.0 0.716 H -57.1 -37.3 161.0 0.716 0.0 HOH
 7.711
 N
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:375 A:375 135.0 0.6 H -43.9 -60.2 135.0 0.6 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 ARG A:375 A:375 156.0 0.693 H -48.5 -54.3 156.0 0.693 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 ARG A:377 A:375 86.0 0.382 H -65.5 -47.8 86.0 0.382 0.0 HOH
 2.664
 NH2
 O
ARG C:377 C:375 86.0 0.382 H -58.8 -47.1 86.0 0.382 0.0 HOH
 2.580
 O
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 ARG A:375 A:375 165.0 0.733 H -48.6 -42.3 165.0 0.733 0.0 HOH
 5.619
 CD
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 ARG A:377 A:375 96.0 0.427 H -62.1 -48.4 96.0 0.427 0.0 HOH
 2.693
 O
 O
ARG B:377 C:375 134.0 0.596 H -61.0 -44.4 134.0 0.596 0.0 HOH
 2.614
 NH2
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 ARG A:377 A:375 105.0 0.467 H -55.8 -46.8 105.0 0.467 0.0
ARG B:377 B:375 108.0 0.48 H -56.4 -46.2 108.0 0.48 0.0
ARG C:377 C:375 96.0 0.427 H -57.3 -45.6 NA NA NA
ARG D:377 D:375 85.0 0.378 H -57.7 -44.6 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 ARG A:375 A:375 162.0 0.72 H -49.7 -48.1 162.0 0.72 0.0 GOL
HOH
 4.253
3.151
 NH1
O
 O2
O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 ARG A:386 A:375 153.0 0.68 H -61.5 -51.3 153.0 0.68 0.0 HOH
 2.871
 NH1
 O
ARG B:386 B:375 151.0 0.671 H -61.3 -47.0 151.0 0.671 0.0 HOH
 2.812
 NH1
 O
ARG C:386 E:375 159.0 0.707 H -62.0 -50.8 NA NA NA
ARG D:386 G:375 156.0 0.693 H -60.4 -48.9 NA NA NA
ARG E:386 M:375 152.0 0.676 H -64.7 -47.1 NA NA NA
ARG F:386 N:375 161.0 0.716 H -67.4 -42.4 NA NA NA
ARG G:386 S:375 158.0 0.702 H -60.6 -48.9 NA NA NA
ARG H:386 T:375 153.0 0.68 H -66.8 -47.9 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 ARG A:377 A:375 101.0 0.449 H -63.5 -46.0 101.0 0.449 0.0
ARG B:377 C:375 103.0 0.458 H -63.4 -47.6 103.0 0.458 0.0 HOH
 9.087
 N
 O
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 ARG A:375 A:375 155.0 0.689 H -55.9 -43.6 155.0 0.689 0.0 HOH
 6.990
 NE
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 ARG A:375 A:375 131.0 0.582 H -62.1 -44.9 131.0 0.582 0.0 HOH
 5.704
 N
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 ARG A:370 A:375 69.0 0.307 H -63.9 -44.0 69.0 0.307 0.0 HOH
 1.777
 HH21
 O
ARG B:370 B:375 150.0 0.667 H -61.4 -44.0 150.0 0.667 0.0 HOH
 2.812
 HH11
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 ARG A:370 A:375 89.0 0.396 H -62.7 -45.0 89.0 0.396 0.0 HOH
 1.961
 HE
 O
ARG B:370 B:375 122.0 0.542 H -62.9 -44.1 122.0 0.542 0.0 HOH
 1.873
 HH22
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 ARG A:375 A:375 121.0 0.538 H -63.8 -45.0 121.0 0.538 0.0 HOH
 2.696
 NH1
 O
ARG B:375 B:375 88.0 0.391 H -63.4 -44.4 88.0 0.391 0.0 HOH
 2.647
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 ARG A:375 A:375 144.0 0.64 H -55.4 -51.7