Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 241818189 . C A CCDS2543.1:NM_000030.2:c.1130aCg>aAg_NP_000021.1:p.377T>K Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1h0c 1 P21549 100.0 0.0 X-RAY
 2003-06-12 THR A:377 A:377 0.0 0.0 H -73.7 -49.4 0.0 0.0 0.0 HOH
 5.192
 CG2
 O
5og0 1 P21549 100.0 0.0 X-RAY
 2017-09-27 THR A:377 A:377 0.0 0.0 H -71.5 -46.6 0.0 0.0 0.0 HOH
 5.963
 CG2
 O
6rv0 1 P21549 100.0 0.0 X-RAY
 2020-04-08 THR A:377 A:377 0.0 0.0 H -79.0 -42.6 0.0 0.0 0.0
6rv1 1 P21549 100.0 0.0 X-RAY
 2020-04-08 THR A:377 A:377 16.0 0.114 H -68.3 -50.4 16.0 0.114 0.0
3r9a 1 P21549 100.0 0.0 X-RAY
 2011-05-11 THR A:379 A:377 1.0 0.007 H -62.5 -47.2 1.0 0.007 0.0 HOH
 3.887
 CG2
 O
THR C:379 C:377 0.0 0.0 H -66.3 -42.3 0.0 0.0 0.0 HOH
 5.348
 O
 O
5ofy 1 P21549 99.74 0.0 X-RAY
 2017-09-27 THR A:377 A:377 0.0 0.0 H -62.4 -43.7 0.0 0.0 0.0 HOH
 9.903
 N
 O
4kyo 1 P21549 99.74 0.0 X-RAY
 2014-11-19 THR A:379 A:377 1.0 0.007 H -58.4 -50.9 1.0 0.007 0.0 BME
HOH
 9.125
5.449
 OG1
O
 S2
O
THR B:379 C:377 3.0 0.021 H -56.7 -51.7 3.0 0.021 0.0 HOH
 3.941
 CG2
 O
4i8a 1 P21549 99.74 0.0 X-RAY
 2013-05-01 THR A:379 A:377 4.0 0.029 H -71.0 -37.8 4.0 0.029 0.0
THR B:379 B:377 1.0 0.007 H -71.6 -39.7 1.0 0.007 0.0
THR C:379 C:377 3.0 0.021 H -71.6 -38.6 NA NA NA
THR D:379 D:377 4.0 0.029 H -70.5 -38.1 NA NA NA
1j04 1 P21549 99.74 0.0 X-RAY
 2003-11-11 THR A:377 A:377 0.0 0.0 H -61.2 -41.3 0.0 0.0 0.0 HOH
 6.661
 N
 O
5luc 1 P21549 99.74 0.0 X-RAY
 2017-09-20 THR A:388 A:377 0.0 0.0 H -59.2 -46.2 0.0 0.0 0.0 HOH
 3.774
 CG2
 O
THR B:388 B:377 1.0 0.007 H -62.8 -46.2 1.0 0.007 0.0 HOH
 3.722
 CG2
 O
THR C:388 E:377 0.0 0.0 H -59.9 -46.6 NA NA NA
THR D:388 G:377 0.0 0.0 H -60.6 -48.1 NA NA NA
THR E:388 M:377 0.0 0.0 H -61.8 -49.4 NA NA NA
THR F:388 N:377 0.0 0.0 H -62.4 -44.8 NA NA NA
THR G:388 S:377 0.0 0.0 H -61.1 -49.2 NA NA NA
THR H:388 T:377 1.0 0.007 H -61.4 -48.9 NA NA NA
4kxk 1 P21549 99.49 0.0 X-RAY
 2014-11-19 THR A:379 A:377 0.0 0.0 H -68.1 -45.5 0.0 0.0 0.0
THR B:379 C:377 0.0 0.0 H -76.9 -39.3 0.0 0.0 0.0
4cbr 1 P21549 99.23 0.0 X-RAY
 2014-07-09 THR A:377 A:377 0.0 0.0 H -73.7 -48.8 0.0 0.0 0.0 HOH
 6.103
 CG2
 O
4cbs 1 P21549 98.72 0.0 X-RAY
 2014-07-09 THR A:377 A:377 2.0 0.014 H -64.4 -44.9 2.0 0.014 0.0 HOH
 5.765
 CB
 O
5f9s 1 P21549 100.0 0.0 X-RAY
 2016-12-21 THR A:372 A:377 0.0 0.0 H -64.2 -49.1 0.0 0.0 0.0 HOH
 2.889
 HB
 O
THR B:372 B:377 0.0 0.0 H -66.3 -45.9 0.0 0.0 0.0 HOH
 2.909
 HG21
 O
5hhy 1 P21549 100.0 0.0 X-RAY
 2017-01-25 THR A:372 A:377 0.0 0.0 H -60.9 -49.0 0.0 0.0 0.0 HOH
 3.032
 HB
 O
THR B:372 B:377 0.0 0.0 H -63.6 -46.9 0.0 0.0 0.0 HOH
 2.970
 HG21
 O
2yob 1 P21549 99.74 0.0 X-RAY
 2013-10-30 THR A:377 A:377 3.0 0.021 H -72.5 -39.7 3.0 0.021 0.0 HOH
 5.547
 O
 O
THR B:377 B:377 0.0 0.0 H -73.1 -30.7 0.0 0.0 0.0 HOH
 5.498
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21549-f1 1 P21549 100.0 0.0 THR A:377 A:377 1.0 0.007 H -64.0 -44.0