Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 27016101 . T A CCDS1729.1:NM_001809.3:c.377gTg>gAg_NP_001800.1:p.126V>E Homo sapiens centromere protein A (CENPA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3an2 1 P49450 100.0 2e-98 X-RAY
 2011-07-20 VAL A:129 A:126 35.0 0.226 T -79.4 41.2 3.0 0.019 0.207 B:B2R4R0:0.206
VAL E:129 E:126 33.0 0.213 T -77.4 36.1 3.0 0.019 0.194 F:B2R4R0:0.194
3wtp 1 P49450 100.0 2e-98 X-RAY
 2014-12-03 VAL A:129 A:126 34.0 0.219 H -62.1 -44.6 2.0 0.013 0.206 B:P62805:0.206
6l49 1 P49450 100.0 2e-98 EM
 2019-12-04 VAL A:129 A:126 36.0 0.232 H -89.3 -19.3 2.0 0.013 0.219 B:P62805:0.219
VAL E:129 E:126 39.0 0.252 H -95.8 -7.9 1.0 0.006 0.246 F:P62805:0.245
7d20 1 P49450 100.0 2e-98 EM
 2021-02-10 VAL A:129 A:126 33.0 0.213 H -50.8 -31.2 0.0 0.0 0.213 F:P62805:0.213
VAL B:129 E:126 29.0 0.187 H -67.7 -44.3 0.0 0.0 0.187 C:P62805:0.187
3r45 1 P49450 100.0 2e-98 X-RAY
 2011-04-06 VAL A:142 A:126 38.0 0.245 H -66.7 -55.7 3.0 0.019 0.226 B:P62805:0.226
 SO4
HOH
 9.609
4.776
 N
C
 O2
O
3nqu 1 P49450 100.0 2e-98 X-RAY
 2010-08-25 VAL A:126 A:126 33.0 0.213 H -62.8 -42.6 2.0 0.013 0.2 B:P62805:0.2
 HOH
 3.653
 CG1
 O
6c0w 1 P49450 100.0 2e-98 EM
 2018-01-17 VAL A:126 A:126 35.0 0.226 H -75.7 -38.8 1.0 0.006 0.22 B:P62805:0.219
VAL E:126 E:126 37.0 0.239 H -69.6 -42.8 2.0 0.013 0.226 F:P62805:0.226
6se0 1 P49450 100.0 2e-98 EM
 2019-08-14 VAL A:126 A:126 46.0 0.297 H -72.1 -30.5 3.0 0.019 0.278 B:P62805:0.277
VAL E:126 E:126 37.0 0.239 H -69.9 -32.5 2.0 0.013 0.226 F:P62805:0.226
6se6 1 P49450 100.0 2e-98 EM
 2019-08-14 VAL A:126 A:126 28.0 0.181 H -67.8 -39.9 0.0 0.0 0.181 B:P62805:0.181
VAL E:126 E:126 28.0 0.181 H -69.8 -38.7 3.0 0.019 0.162 F:P62805:0.161
6see 1 P49450 100.0 2e-98 EM
 2019-08-14 VAL A:126 A:126 29.0 0.187 H -68.7 -42.1 1.0 0.006 0.181 B:P62805:0.181
VAL E:126 E:126 26.0 0.168 H -68.5 -38.7 0.0 0.0 0.168 F:P62805:0.168
6sef 1 P49450 100.0 2e-98 EM
 2019-08-14 VAL A:126 A:126 34.0 0.219 H -71.2 -30.1 5.0 0.032 0.187 B:P62805:0.187
VAL E:126 E:126 32.0 0.206 H -71.1 -28.9 13.0 0.084 0.122 F:P62805:0.123
6seg 1 P49450 100.0 2e-98 EM
 2019-08-14 VAL A:126 A:126 33.0 0.213 H -68.5 -40.5 2.0 0.013 0.2 B:P62805:0.2
VAL E:126 E:126 32.0 0.206 H -68.4 -37.5 7.0 0.045 0.161 F:P62805:0.161
6tem 1 P49450 100.0 2e-98 EM
 2020-04-08 VAL A:126 A:126 30.0 0.194 H -62.7 -49.0 0.0 0.0 0.194 B:P62799:0.194
VAL E:126 E:126 29.0 0.187 H -60.4 -44.8 0.0 0.0 0.187 F:P62799:0.187
6buz 1 P49450 100.0 3e-98 EM
 2017-12-20 VAL A:146 A:126 42.0 0.271 H -81.6 -56.1 3.0 0.019 0.252 B:P62805:0.252
VAL E:146 E:126 41.0 0.265 H -81.5 -56.1 4.0 0.026 0.239 F:P62805:0.239
6e0c 1 P49450 100.0 3e-98 EM
 2019-05-22 VAL A:144 A:126 32.0 0.206 H -69.8 -39.2 2.0 0.013 0.193 B:P62805:0.194
VAL E:144 E:126 33.0 0.213 H -69.0 -39.2 3.0 0.019 0.194 F:P62805:0.194
6e0p 1 P49450 100.0 3e-98 EM
 2019-05-22 VAL A:144 A:126 35.0 0.226 H -67.4 -38.4 3.0 0.019 0.207 B:P62805:0.206
VAL E:144 E:126 35.0 0.226 H -67.4 -38.4 3.0 0.019 0.207 F:P62805:0.206
6o1d 1 P49450 100.0 3e-98 EM
 2019-05-22 VAL A:144 A:126 29.0 0.187 H -67.0 -40.3 0.0 0.0 0.187 B:P62805:0.187
VAL E:144 E:126 32.0 0.206 H -67.4 -37.0 2.0 0.013 0.193 F:P62805:0.194
6muo 1 P49450 100.0 3e-70 EM
 2019-07-24 VAL A:89 A:126 45.0 0.29 H -108.1 -36.9 4.0 0.026 0.264 B:P62805:0.265
VAL E:89 E:126 41.0 0.265 H -98.0 -38.8 3.0 0.019 0.246 F:P62805:0.245
6mup 1 P49450 100.0 3e-70 EM
 2019-07-24 VAL A:89 A:126 36.0 0.232 H -65.3 -32.3 0.0 0.0 0.232 B:P62805:0.232
VAL E:89 E:126 32.0 0.206 H -71.1 -36.8 1.0 0.006 0.2 F:P62805:0.2
3nqj 1 P49450 100.0 1e-53 X-RAY
 2010-08-25 VAL A:68 A:126 33.0 0.213 H -74.9 -40.4 3.0 0.019 0.194 B:P62805:0.194
 HOH
 5.257
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49450-f1 1 P49450 100.0 9e-99 VAL A:126 A:126 30.0 0.194 H -68.1 -42.2