Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29001839 . T A CCDS33169.1:NM_002709.2:c.349Ttc>Atc_NP_002700.1:p.117F>I Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
2004-06-22 PHE A:120 A:118 1.0 0.005 E -127.4 132.0 1.0 0.005 0.0 HOH
3.572
CD1
O
1fjm 1 P08129 88.79 0.0 X-RAY
1996-06-20 PHE A:118 A:118 1.0 0.005 E -130.6 129.4 1.0 0.005 0.0 HOH
3.692
CD1
O
PHE B:118 B:118 1.0 0.005 E -144.9 126.0 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
2012-09-19 PHE A:119 A:118 0.0 0.0 E -142.0 124.2 0.0 0.0 0.0 HOH
9.288
N
O
PHE B:119 B:118 0.0 0.0 E -136.9 119.4 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
2018-11-21 PHE A:119 A:118 1.0 0.005 E -146.3 125.0 1.0 0.005 0.0 HOH
3.932
CD1
O
6g0j 1 P62136 88.79 0.0 X-RAY
2018-11-21 PHE A:119 A:118 1.0 0.005 E -142.5 125.3 1.0 0.005 0.0 HOH
3.995
CD1
O
3egg 1 P62136 89.26 0.0 X-RAY
2010-03-23 PHE A:117 A:118 0.0 0.0 E -146.7 127.4 0.0 0.0 0.0 GOL
GOL
HOH
9.156
8.092
4.839
N
O
O
O3
C3
O
PHE B:117 B:118 1.0 0.005 E -151.7 126.1 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
2010-03-23 PHE A:117 A:118 0.0 0.0 E -150.1 126.9 0.0 0.0 0.0 GOL
GOL
HOH
9.093
8.100
3.737
N
O
CD2
O3
C1
O
PHE B:117 B:118 1.0 0.005 E -150.4 126.8 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
2010-03-23 PHE A:117 A:118 0.0 0.0 E -148.4 127.4 0.0 0.0 0.0 HOH
3.695
CD2
O
PHE B:117 B:118 0.0 0.0 E -149.0 124.0 0.0 0.0 0.0 HOH
3.780
CD2
O
6ghm 1 P62136 89.26 0.0 X-RAY
2019-02-27 PHE A:117 A:118 1.0 0.005 E -141.4 128.6 1.0 0.005 0.0 EDO
HOH
7.950
3.741
O
CD1
O2
O
PHE B:117 B:118 0.0 0.0 E -142.7 121.8 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
2019-05-15 PHE A:127 A:118 0.0 0.0 E -151.0 124.8 0.0 0.0 0.0
PHE B:127 B:118 0.0 0.0 E -151.3 126.8 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
2020-11-18 PHE A:119 A:118 0.0 0.0 E -141.4 125.5 0.0 0.0 0.0 HOH
3.852
CD2
O
5zqv 1 P62137 89.23 0.0 X-RAY
2019-03-13 PHE A:118 A:118 0.0 0.0 E -153.1 131.0 0.0 0.0 0.0
PHE B:118 B:118 2.0 0.01 E -133.6 129.4 NA NA NA
PHE C:118 C:118 0.0 0.0 E -136.7 135.1 0.0 0.0 0.0
PHE D:118 D:118 0.0 0.0 E -146.1 128.3 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
2015-03-25 PHE D:118 D:118 0.0 0.0 E -143.3 126.2 NA NA NA
PHE F:118 F:118 0.0 0.0 E -143.2 126.2 NA NA NA
PHE H:118 H:118 0.0 0.0 E -143.3 126.2 NA NA NA
PHE J:118 J:118 0.0 0.0 E -143.3 126.3 0.0 0.0 0.0
PHE N:118 N:118 0.0 0.0 E -143.0 126.3 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
2002-05-22 PHE A:118 A:118 0.0 0.0 E -138.6 129.2 0.0 0.0 0.0 HOH
3.836
CD1
O
PHE B:118 B:118 1.0 0.005 E -137.3 121.3 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
2001-08-15 PHE A:118 A:118 1.0 0.005 E -141.0 124.7 1.0 0.005 0.0 HOH
3.813
CD1
O
2bcd 1 P36873 89.06 0.0 X-RAY
2006-01-17 PHE A:118 A:118 1.0 0.005 E -141.0 124.5 1.0 0.005 0.0 HOH
3.428
CD1
O
2bdx 1 P36873 89.06 0.0 X-RAY
2006-01-17 PHE A:118 A:118 0.0 0.0 E -146.0 123.7 0.0 0.0 0.0 HOH
3.587
CD1
O
4ut2 1 P36873 89.06 0.0 X-RAY
2015-07-22 PHE A:118 A:118 1.0 0.005 E -145.6 122.8 1.0 0.005 0.0 HOH
3.596
CD1
O
PHE B:118 B:118 0.0 0.0 E -145.7 122.0 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
2015-07-22 PHE A:118 A:118 1.0 0.005 E -148.9 125.2 1.0 0.005 0.0 HOH
3.988
CD2
O
4ut3 2 P36873 89.06 0.0 X-RAY
2015-07-22 PHE B:118 B:118 1.0 0.005 E -149.0 126.3 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
2007-07-17 PHE A:124 A:118 1.0 0.005 E -134.5 127.7 1.0 0.005 0.0 HOH
4.755
O
O
PHE C:124 B:118 1.0 0.005 E -133.7 126.4 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
2007-07-17 PHE A:124 A:118 1.0 0.005 E -142.6 120.9 1.0 0.005 0.0 HOH
3.789
CD1
O
PHE C:124 B:118 1.0 0.005 E -135.8 126.3 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
2020-09-30 PHE A:117 D:117 0.0 0.0 E -157.4 121.0 0.0 0.0 0.0 HOH
2.995
HD1
O
PHE B:117 A:117 0.0 0.0 E -151.4 123.2 NA NA NA
PHE C:117 F:117 0.0 0.0 E -158.7 121.0 NA NA NA
PHE D:117 I:117 0.0 0.0 E -146.9 121.6 NA NA NA
PHE E:117 L:117 0.0 0.0 E -143.4 123.3 NA NA NA
PHE F:117 O:117 0.0 0.0 E -148.4 120.5 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
2012-10-31 PHE A:117 A:118 1.0 0.005 E -143.7 127.0 1.0 0.005 0.0 GOL
GOL
HOH
4.638
6.809
2.810
N
H
HD2
H12
H31
O
PHE C:117 C:118 1.0 0.005 E -147.9 123.9 NA NA NA
PHE E:117 E:118 1.0 0.005 E -144.0 125.9 NA NA NA
PHE G:117 G:118 0.0 0.0 E -146.8 126.6 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
2020-09-30 PHE A:117 A:118 1.0 0.005 E -147.8 126.7 1.0 0.005 0.0 HOH
2.840
HD1
O
PHE C:117 B:118 0.0 0.0 E -148.9 125.9 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
2019-09-18 PHE A:123 A:118 1.0 0.005 E -141.8 130.9 1.0 0.005 0.0 HOH
4.734
O
O
PHE B:123 B:118 0.0 0.0 E -142.8 131.3 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
2019-09-18 PHE A:123 A:118 0.0 0.0 E -136.1 126.8 0.0 0.0 0.0 CL
HOH
5.475
8.352
N
N
CL
O
3n5u 1 P62136 92.0 0.0 X-RAY
2010-08-11 PHE A:118 A:118 0.0 0.0 E -155.6 120.0 0.0 0.0 0.0
PHE B:118 B:118 0.0 0.0 E -155.6 120.0 0.0 0.0 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 PHE A:117 A:118 1.0 0.005 E -152.6 125.1 1.0 0.005 0.0 HOH
2.841
HD2
O
PHE C:117 B:118 0.0 0.0 E -150.9 124.4 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 PHE A:117 A:118 1.0 0.005 E -149.0 125.7 1.0 0.005 0.0 HOH
2.812
HD2
O
PHE C:117 B:118 0.0 0.0 E -150.3 124.0 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
2008-11-04 PHE A:117 A:118 0.0 0.0 E -146.8 125.6 0.0 0.0 0.0 GOL
HOH
7.167
3.670
O
CD2
C3
O
PHE B:117 B:118 0.0 0.0 E -147.9 125.9 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
2008-11-04 PHE A:117 A:118 1.0 0.005 E -150.8 123.6 1.0 0.005 0.0 GOL
NA
HOH
7.597
3.686
4.756
O
CD2
O
O3
NA
O
PHE B:117 B:118 1.0 0.005 E -148.0 125.5 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
2014-03-26 PHE A:117 A:118 1.0 0.005 E -147.8 126.4 1.0 0.005 0.0 HOH
3.700
CD1
O
PHE B:117 B:118 1.0 0.005 E -147.2 128.4 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
2014-03-26 PHE A:117 A:118 0.0 0.0 E -144.6 124.2 0.0 0.0 0.0 GOL
HOH
7.179
3.657
N
CD1
O1
O
4mp0 1 P62136 92.57 0.0 X-RAY
2014-03-26 PHE A:117 A:118 1.0 0.005 E -141.8 125.5 1.0 0.005 0.0 GOL
HOH
7.537
3.759
O
CD1
O1
O
PHE B:117 C:118 0.0 0.0 E -142.7 125.3 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
2015-07-01 PHE A:117 A:118 0.0 0.0 E -139.0 128.1 0.0 0.0 0.0 GOL
HOH
7.539
3.876
N
CD1
O1
O
PHE C:117 C:118 0.0 0.0 E -139.4 127.6 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
2016-10-05 PHE A:117 A:118 1.0 0.005 E -141.1 124.3 1.0 0.005 0.0 HOH
3.723
CD1
O
PHE C:117 C:118 1.0 0.005 E -141.0 124.3 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
2017-11-29 PHE A:117 A:118 1.0 0.005 E -146.5 125.3 1.0 0.005 0.0 DMS
HOH
8.184
3.888
O
CD1
C2
O
PHE B:117 B:118 1.0 0.005 E -143.0 128.9 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
2019-01-23 PHE A:117 A:118 0.0 0.0 E -154.8 123.8 0.0 0.0 0.0 HOH
4.920
O
O
PHE C:117 C:118 1.0 0.005 E -141.0 124.8 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
2019-01-23 PHE A:117 A:118 0.0 0.0 E -148.1 126.7 0.0 0.0 0.0 HOH
3.651
CD2
O
6zee 1 P62136 92.57 0.0 X-RAY
2020-09-30 PHE A:117 P:118 0.0 0.0 E -154.4 124.8 0.0 0.0 0.0 EDO
EDO
HOH
7.776
8.813
2.960
HE2
HD2
HD2
HO2
HO2
O
PHE B:117 Q:118 0.0 0.0 E -154.5 120.7 0.0 0.0 0.0 HOH
4.823
O
O
PHE C:117 B:118 0.0 0.0 E -151.6 122.9 0.0 0.0 0.0 EDO
EDO
HOH
7.417
8.088
3.027
HE2
HA
HD2
H21
HO1
O
PHE D:117 A:118 0.0 0.0 E -147.1 123.6 0.0 0.0 0.0 EDO
EDO
HOH
7.457
6.551
2.542
HE2
H
HD2
HO1
H11
O
PHE E:117 I:118 0.0 0.0 E -150.6 122.3 0.0 0.0 0.0 HOH
2.853
HD2
O
PHE F:117 K:118 1.0 0.005 E -153.7 122.3 1.0 0.005 0.0 EDO
HOH
6.244
2.912
H
HD2
H11
O
6zef 1 P62136 92.57 0.0 X-RAY
2020-09-30 PHE A:117 A:118 1.0 0.005 E -148.8 124.0 1.0 0.005 0.0 EDO
EDO
EDO
HOH
5.017
7.452
7.904
2.881
H
H
HD1
HD1
H21
O2
H11
O
PHE B:117 B:118 1.0 0.005 E -151.4 123.5 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
2016-10-05 PHE A:115 A:118 1.0 0.005 E -151.3 126.1 1.0 0.005 0.0 GOL
GOL
HOH
7.515
9.063
3.654
O
N
CD1
C1
O3
O
5j28 1 P36873 92.57 0.0 X-RAY
2016-10-05 PHE A:115 A:118 2.0 0.01 E -134.5 126.6 2.0 0.01 0.0 HOH
2.946
CD1
O
PHE B:115 B:118 0.0 0.0 E -158.9 123.7 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
2019-09-18 PHE A:117 A:118 1.0 0.005 E -147.1 127.5 1.0 0.005 0.0 HOH
3.655
CD1
O
PHE B:117 B:118 1.0 0.005 E -146.7 127.3 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
2019-09-18 PHE A:117 A:118 0.0 0.0 E -148.1 127.0 0.0 0.0 0.0 HOH
3.805
CD1
O
PHE B:117 B:118 0.0 0.0 E -147.9 126.7 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
2019-09-18 PHE A:117 A:118 0.0 0.0 E -148.0 127.2 0.0 0.0 0.0 HOH
3.712
CD2
O
PHE B:117 B:118 0.0 0.0 E -147.4 126.6 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
2019-09-18 PHE A:117 A:118 0.0 0.0 E -146.4 125.9 0.0 0.0 0.0 GOL
GOL
HOH
5.574
7.773
3.792
N
O
CD1
C3
O3
O
PHE B:117 B:118 0.0 0.0 E -147.1 126.4 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
2019-03-13 PHE A:112 A:118 0.0 0.0 -167.5 118.7 0.0 0.0 0.0
PHE B:112 B:118 0.0 0.0 E -158.5 113.2 NA NA NA
PHE C:112 C:118 0.0 0.0 E -167.5 119.4 NA NA NA
PHE D:112 D:118 0.0 0.0 E -162.4 118.5 NA NA NA
PHE E:112 E:118 0.0 0.0 E -159.6 120.8 NA NA NA
PHE F:112 F:118 0.0 0.0 E -163.6 123.4 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
2015-03-25 PHE A:113 A:118 0.0 0.0 E -142.8 126.6 0.0 0.0 0.0 HOH
3.701
CD2
O
PHE C:113 C:118 0.0 0.0 E -147.2 123.6 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
2015-03-25 PHE A:113 A:118 0.0 0.0 E -145.9 127.2 0.0 0.0 0.0 HOH
3.693
CD1
O
PHE C:113 C:118 0.0 0.0 E -143.8 126.2 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
2015-03-25 PHE A:113 A:118 0.0 0.0 E -144.0 122.8 0.0 0.0 0.0 HOH
2.945
HD1
O
7nzm 2 P62139 92.52 0.0 EM
2021-09-29 PHE B:112 B:118 0.0 0.0 E -148.7 126.1 0.0 0.0 0.0
1u32 1 P36873 90.78 0.0 X-RAY
2004-08-17 PHE A:113 A:118 1.0 0.005 E -143.0 123.9 1.0 0.005 0.0 HOH
4.052
CD1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 PHE A:117 A:117 0.0 0.0 E -132.2 119.9
af-p62136-f1 1 P62136 88.79 0.0 PHE A:118 A:118 0.0 0.0 E -133.9 120.2
af-p36873-f1 1 P36873 89.06 0.0 PHE A:118 A:118 0.0 0.0 E -137.9 118.9