Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29004681 . G A CCDS33169.1:NM_002709.2:c.493Gat>Aat_NP_002700.1:p.165D>N Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
2004-06-22 ASP A:168 A:166 47.0 0.313 T 41.4 28.0 47.0 0.313 0.0 HOH
2.989
OD2
O
1fjm 1 P08129 88.79 0.0 X-RAY
1996-06-20 ASP A:166 A:166 53.0 0.353 T 40.9 45.0 53.0 0.353 0.0 HOH
3.190
N
O
ASP B:166 B:166 56.0 0.373 T 46.7 34.5 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
2012-09-19 ASP A:167 A:166 64.0 0.427 T 48.5 42.5 60.0 0.4 0.027 C:None:0.027
HOH
9.281
O
O
ASP B:167 B:166 58.0 0.387 T 56.8 25.2 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
2018-11-21 ASP A:167 A:166 47.0 0.313 T 49.3 44.1 47.0 0.313 0.0 HOH
3.395
N
O
6g0j 1 P62136 88.79 0.0 X-RAY
2018-11-21 ASP A:167 A:166 50.0 0.333 T 52.7 39.6 50.0 0.333 0.0 HOH
2.945
OD2
O
3egg 1 P62136 89.26 0.0 X-RAY
2010-03-23 ASP A:165 A:166 50.0 0.333 T 50.4 40.7 50.0 0.333 0.0 GOL
HOH
9.579
2.465
OD2
OD1
O1
O
ASP B:165 B:166 42.0 0.28 T 44.7 39.6 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
2010-03-23 ASP A:165 A:166 49.0 0.327 T 46.8 37.9 46.0 0.307 0.02 C:O35274:0.02
GOL
GOL
HOH
9.693
9.589
2.454
OD2
N
OD1
O1
O1
O
ASP B:165 B:166 48.0 0.32 T 46.6 38.9 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
2010-03-23 ASP A:165 A:166 48.0 0.32 T 50.9 35.3 48.0 0.32 0.0 HOH
2.563
O
O
ASP B:165 B:166 52.0 0.347 T 44.0 38.7 52.0 0.347 0.0 HOH
2.554
O
O
6ghm 1 P62136 89.26 0.0 X-RAY
2019-02-27 ASP A:165 A:166 55.0 0.367 T 49.4 37.4 39.0 0.26 0.107 D:Q13625:0.107
EDO
GOL
HOH
9.940
3.166
3.192
N
OD2
N
O1
O3
O
ASP B:165 B:166 52.0 0.347 T 51.5 35.0 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
2019-05-15 ASP A:175 A:166 54.0 0.36 T 45.6 39.7 42.0 0.28 0.08 D:Q8WUF5:0.08
ASP B:175 B:166 50.0 0.333 T 44.9 39.0 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
2020-11-18 ASP A:167 A:166 51.0 0.34 T 49.6 41.1 51.0 0.34 0.0 HOH
2.513
O
O
5zqv 1 P62137 89.23 0.0 X-RAY
2019-03-13 ASP A:166 A:166 52.0 0.347 T 56.4 35.9 26.0 0.173 0.174 E:Q16821:0.173
ASP B:166 B:166 51.0 0.34 T 58.3 35.9 NA NA NA
ASP C:166 C:166 66.0 0.44 T 57.3 33.0 34.0 0.227 0.213 H:Q16821:0.213
ASP D:166 D:166 57.0 0.38 T 55.4 32.4 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
2015-03-25 ASP D:166 D:166 59.0 0.393 T 43.2 40.6 NA NA NA
ASP F:166 F:166 59.0 0.393 T 43.2 40.7 NA NA NA
ASP H:166 H:166 57.0 0.38 T 43.2 40.7 NA NA NA
ASP J:166 J:166 59.0 0.393 T 43.2 40.6 34.0 0.227 0.166 K:Q5SWA1:0.167
ASP N:166 N:166 58.0 0.387 T 43.2 40.6 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
2002-05-22 ASP A:166 A:166 48.0 0.32 T 43.5 42.4 48.0 0.32 0.0 HOH
3.214
N
O
ASP B:166 B:166 56.0 0.373 T 50.5 36.6 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
2001-08-15 ASP A:166 A:166 50.0 0.333 T 46.5 41.5 50.0 0.333 0.0 BME
HOH
7.342
3.257
OD2
OD1
S2
O
2bcd 1 P36873 89.06 0.0 X-RAY
2006-01-17 ASP A:166 A:166 49.0 0.327 T 56.1 47.3 49.0 0.327 0.0 HOH
3.390
N
O
2bdx 1 P36873 89.06 0.0 X-RAY
2006-01-17 ASP A:166 A:166 42.0 0.28 T 49.2 44.7 42.0 0.28 0.0 HOH
7.677
OD2
O
4ut2 1 P36873 89.06 0.0 X-RAY
2015-07-22 ASP A:166 A:166 55.0 0.367 T 49.9 40.3 55.0 0.367 0.0 HOH
3.128
N
O
ASP B:166 B:166 52.0 0.347 T 50.1 40.6 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
2015-07-22 ASP A:166 A:166 46.0 0.307 T 46.4 38.4 46.0 0.307 0.0 HOH
3.622
N
O
4ut3 2 P36873 89.06 0.0 X-RAY
2015-07-22 ASP B:166 B:166 45.0 0.3 T 46.1 38.6 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
2007-07-17 ASP A:172 A:166 55.0 0.367 T 43.8 40.8 15.0 0.1 0.267 B:Q9DCL8:0.267
HOH
3.321
N
O
ASP C:172 B:166 58.0 0.387 T 44.1 42.7 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
2007-07-17 ASP A:172 A:166 62.0 0.413 T 46.3 41.1 12.0 0.08 0.333 B:Q9DCL8:0.333
HOH
3.303
N
O
ASP C:172 B:166 59.0 0.393 T 48.7 41.6 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
2020-09-30 ASP A:165 D:165 54.0 0.36 T 54.3 33.3 54.0 0.36 0.0 HOH
2.281
OD2
O
ASP B:165 A:165 57.0 0.38 T 51.9 39.7 NA NA NA
ASP C:165 F:165 57.0 0.38 T 47.8 41.7 NA NA NA
ASP D:165 I:165 53.0 0.353 T 51.4 38.5 NA NA NA
ASP E:165 L:165 52.0 0.347 T 54.4 40.4 NA NA NA
ASP F:165 O:165 57.0 0.38 T 50.7 37.9 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
2012-10-31 ASP A:165 A:166 53.0 0.353 T 47.9 40.1 42.0 0.28 0.073 B:Q12972:0.073
GOL
GOL
HOH
6.329
8.852
2.868
H
H
O
HO3
HO1
O
ASP C:165 C:166 57.0 0.38 T 50.8 40.7 NA NA NA
ASP E:165 E:166 55.0 0.367 T 48.4 40.3 NA NA NA
ASP G:165 G:166 57.0 0.38 T 41.8 44.5 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
2020-09-30 ASP A:165 A:166 50.0 0.333 T 50.8 37.7 50.0 0.333 0.0 HOH
2.961
O
O
ASP C:165 B:166 52.0 0.347 T 47.6 40.9 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
2019-09-18 ASP A:171 A:166 54.0 0.36 T 51.7 37.4 54.0 0.36 0.0 MPD
HOH
9.209
9.943
O
N
C5
O
ASP B:171 B:166 61.0 0.407 T 50.8 38.4 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
2019-09-18 ASP A:171 A:166 45.0 0.3 T 56.3 37.3 45.0 0.3 0.0 HOH
9.800
OD1
O
3n5u 1 P62136 92.0 0.0 X-RAY
2010-08-11 ASP A:166 A:166 49.0 0.327 T 54.9 27.1 49.0 0.327 0.0
ASP B:166 B:166 47.0 0.313 T 55.4 27.5 47.0 0.313 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 ASP A:165 A:166 60.0 0.4 T 52.7 35.7 59.0 0.393 0.007 B:Q4VY12:0.007
HOH
2.689
O
O
ASP C:165 B:166 53.0 0.353 T 47.7 41.7 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 ASP A:165 A:166 50.0 0.333 T 55.6 34.8 49.0 0.327 0.006 B:Q4VY12:0.007
HOH
2.604
HA
O
ASP C:165 B:166 49.0 0.327 T 50.9 38.9 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
2008-11-04 ASP A:165 A:166 62.0 0.413 T 44.7 42.1 62.0 0.413 0.0 GOL
HOH
9.879
2.694
N
OD2
O1
O
ASP B:165 B:166 49.0 0.327 T 47.8 43.0 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
2008-11-04 ASP A:165 A:166 57.0 0.38 T 47.0 42.1 57.0 0.38 0.0 GOL
HOH
9.895
2.686
N
OD1
O1
O
ASP B:165 B:166 51.0 0.34 T 47.5 45.0 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
2014-03-26 ASP A:165 A:166 57.0 0.38 T 47.8 39.3 57.0 0.38 0.0 HOH
2.662
OD1
O
ASP B:165 B:166 55.0 0.367 T 47.1 41.0 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
2014-03-26 ASP A:165 A:166 59.0 0.393 T 40.5 45.6 34.0 0.227 0.166 B:O55000:0.167
GOL
HOH
9.912
3.041
N
O
O3
O
4mp0 1 P62136 92.57 0.0 X-RAY
2014-03-26 ASP A:165 A:166 58.0 0.387 T 49.6 39.5 30.0 0.2 0.187 C:O55000:0.187
GOL
HOH
9.659
2.664
N
O
O3
O
ASP B:165 C:166 70.0 0.467 T 50.1 39.9 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
2015-07-01 ASP A:165 A:166 53.0 0.353 T 51.7 37.1 23.0 0.153 0.2 B:O75807:0.2
GOL
HOH
9.860
3.213
N
N
O3
O
ASP C:165 C:166 55.0 0.367 T 52.2 36.5 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
2016-10-05 ASP A:165 A:166 52.0 0.347 T 53.3 35.8 29.0 0.193 0.154 B:Q69YH5:0.153
HOH
3.369
N
O
ASP C:165 C:166 51.0 0.34 T 53.5 35.9 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
2017-11-29 ASP A:165 A:166 57.0 0.38 T 55.0 35.1 57.0 0.38 0.0 DMS
HOH
9.644
2.978
N
O
O
O
ASP B:165 B:166 50.0 0.333 T 53.4 38.2 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
2019-01-23 ASP A:165 A:166 53.0 0.353 T 51.8 39.2 11.0 0.073 0.28 B:Q05C46:0.28
HOH
2.998
N
O
ASP C:165 C:166 60.0 0.4 T 54.9 36.1 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
2019-01-23 ASP A:165 A:166 55.0 0.367 T 52.0 34.5 55.0 0.367 0.0 HOH
2.719
O
O
6zee 1 P62136 92.57 0.0 X-RAY
2020-09-30 ASP A:165 P:166 56.0 0.373 T 52.6 36.4 56.0 0.373 0.0 EDO
HOH
9.326
2.937
OD2
OD2
H12
O
ASP B:165 Q:166 45.0 0.3 T 54.8 38.3 45.0 0.3 0.0 HOH
6.110
O
O
ASP C:165 B:166 55.0 0.367 T 49.5 39.4 55.0 0.367 0.0 HOH
3.117
H
O
ASP D:165 A:166 50.0 0.333 T 51.5 41.0 50.0 0.333 0.0 EDO
HOH
8.699
2.967
H
H
H22
O
ASP E:165 I:166 46.0 0.307 T 49.8 39.7 46.0 0.307 0.0 HOH
2.978
H
O
ASP F:165 K:166 49.0 0.327 T 46.9 41.5 49.0 0.327 0.0 EDO
HOH
8.986
2.668
H
OD1
H22
O
6zef 1 P62136 92.57 0.0 X-RAY
2020-09-30 ASP A:165 A:166 46.0 0.307 T 55.2 29.6 15.0 0.1 0.207 C:Q4VY12:0.207
EDO
EDO
EDO
HOH
6.255
9.899
8.534
2.865
H
H
H
O
H12
H11
HO1
O
ASP B:165 B:166 53.0 0.353 T 54.1 31.3 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
2016-10-05 ASP A:163 A:166 56.0 0.373 T 51.6 35.0 28.0 0.187 0.186 B:Q69YH5:0.187
GOL
NA
HOH
9.990
7.190
2.559
N
C
OD2
O3
NA
O
5j28 1 P36873 92.57 0.0 X-RAY
2016-10-05 ASP A:163 A:166 61.0 0.407 T 55.1 23.3 58.0 0.387 0.02 C:P46013:0.02
NA
HOH
7.414
3.075
C
N
NA
O
ASP B:163 B:166 54.0 0.36 T 56.2 32.1 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
2019-09-18 ASP A:165 A:166 57.0 0.38 T 47.8 39.9 57.0 0.38 0.0 HOH
2.574
OD1
O
ASP B:165 B:166 51.0 0.34 T 47.9 42.0 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
2019-09-18 ASP A:165 A:166 57.0 0.38 T 47.9 41.7 57.0 0.38 0.0 HOH
2.796
OD2
O
ASP B:165 B:166 46.0 0.307 T 48.7 40.6 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
2019-09-18 ASP A:165 A:166 58.0 0.387 T 47.6 41.5 58.0 0.387 0.0 HOH
2.538
OD1
O
ASP B:165 B:166 56.0 0.373 T 48.1 39.9 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
2019-09-18 ASP A:165 A:166 53.0 0.353 T 50.7 39.1 53.0 0.353 0.0 GOL
GOL
HOH
7.256
9.692
2.864
OD1
N
O
O2
O1
O
ASP B:165 B:166 55.0 0.367 T 48.5 42.9 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
2019-03-13 ASP A:160 A:166 55.0 0.367 T 58.0 45.5 29.0 0.193 0.174 G:Q86XI6:0.173
ASP B:160 B:166 56.0 0.373 T 56.7 42.0 NA NA NA
ASP C:160 C:166 62.0 0.413 T 58.9 37.3 NA NA NA
ASP D:160 D:166 58.0 0.387 T 56.1 42.4 NA NA NA
ASP E:160 E:166 51.0 0.34 T 56.7 43.5 NA NA NA
ASP F:160 F:166 55.0 0.367 T 56.2 40.1 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
2015-03-25 ASP A:161 A:166 55.0 0.367 T 42.6 40.4 34.0 0.227 0.14 B:Q5SWA1:0.14
HOH
2.850
OD2
O
ASP C:161 C:166 50.0 0.333 T 44.9 39.8 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
2015-03-25 ASP A:161 A:166 59.0 0.393 T 45.9 41.4 35.0 0.233 0.16 B:Q5SWA1:0.16
HOH
2.713
O
O
ASP C:161 C:166 52.0 0.347 T 48.8 39.8 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
2015-03-25 ASP A:161 A:166 55.0 0.367 T 48.2 36.3 33.0 0.22 0.147 B:Q5SWA1:0.147
HOH
2.901
H
O
7nzm 2 P62139 92.52 0.0 EM
2021-09-29 ASP B:160 B:166 77.0 0.513 T 46.0 38.1 77.0 0.513 0.0
1u32 1 P36873 90.78 0.0 X-RAY
2004-08-17 ASP A:161 A:166 49.0 0.327 T 49.4 40.7 49.0 0.327 0.0 BME
HOH
7.644
2.964
OD2
OD1
S2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 ASP A:165 A:165 55.0 0.367 T 45.7 39.7
af-p62136-f1 1 P62136 88.79 0.0 ASP A:166 A:166 56.0 0.373 T 43.3 41.4
af-p36873-f1 1 P36873 89.06 0.0 ASP A:166 A:166 52.0 0.347 T 43.2 42.6