Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 37586850 . A C CCDS1790.1:NM_012413.3:c.395aAa>aCa_NP_036545.1:p.132K>T Homo sapiens glutaminyl-peptide cyclotransferase (QPCT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ywy 1 Q16769 99.45 0.0 X-RAY
 2015-08-05 LYS A:132 A:132 50.0 0.25 S -64.2 -34.7 50.0 0.25 0.0 EDO
EDO
HOH
 5.808
6.146
2.668
 O
N
O
 C2
O2
O
LYS B:132 B:132 50.0 0.25 S -67.8 -40.4 NA NA NA
LYS C:132 C:132 49.0 0.245 S -64.6 -41.1 NA NA NA
2afm 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 51.0 0.255 S -67.7 -37.0 51.0 0.255 0.0 HOH
 2.815
 O
 O
LYS B:100 B:132 69.0 0.345 S -52.4 -43.4 NA NA NA
2afo 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 52.0 0.26 S -58.2 -48.1 52.0 0.26 0.0 HOH
 2.715
 O
 O
LYS B:100 B:132 64.0 0.32 S -49.7 -38.7 NA NA NA
2afw 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 50.0 0.25 S -67.4 -36.2 50.0 0.25 0.0 HOH
 2.862
 O
 O
LYS B:100 B:132 68.0 0.34 S -54.8 -42.1 NA NA NA
2afx 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 52.0 0.26 S -70.2 -34.4 52.0 0.26 0.0 HOH
 2.888
 O
 O
LYS B:100 B:132 71.0 0.355 S -70.1 -38.7 NA NA NA
2afz 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 49.0 0.245 S -68.7 -36.2 49.0 0.245 0.0 HOH
 2.860
 O
 O
LYS B:100 B:132 63.0 0.315 S -63.9 -37.6 NA NA NA
3pbb 1 Q16769 100.0 0.0 X-RAY
 2011-02-02 LYS A:100 A:132 65.0 0.325 S -34.0 -48.5 65.0 0.325 0.0 HOH
 2.475
 NZ
 O
LYS B:100 B:132 73.0 0.365 S -67.4 -44.5 NA NA NA
2zef 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 49.0 0.245 S -66.4 -37.6 49.0 0.245 0.0 HOH
 2.866
 O
 O
LYS B:100 B:132 62.0 0.31 S -53.9 -45.4 NA NA NA
2zed 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 51.0 0.255 S -70.9 -37.4 51.0 0.255 0.0 HOH
 2.897
 O
 O
LYS B:100 B:132 69.0 0.345 S -59.1 -41.9 NA NA NA
2afu 1 Q16769 99.7 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 52.0 0.26 S -31.3 -48.1 52.0 0.26 0.0 HOH
 2.783
 O
 O
LYS B:100 B:132 61.0 0.305 S -33.9 -39.7 NA NA NA
2zeh 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 49.0 0.245 S -67.9 -39.7 49.0 0.245 0.0 HOH
 2.879
 O
 O
LYS B:100 B:132 66.0 0.33 S -56.4 -40.7 NA NA NA
2zeo 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 50.0 0.25 S -68.6 -38.4 50.0 0.25 0.0 HOH
 2.883
 O
 O
LYS B:100 B:132 69.0 0.345 S -61.7 -44.3 NA NA NA
2zee 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 50.0 0.25 S -57.3 -43.6 50.0 0.25 0.0 HOH
 2.692
 NZ
 O
LYS B:100 B:132 69.0 0.345 S -57.9 -40.9 NA NA NA
3pbe 1 Q16769 99.7 0.0 X-RAY
 2011-02-02 LYS A:100 A:132 45.0 0.225 S -64.5 -42.9 45.0 0.225 0.0 HOH
 2.853
 O
 O
LYS B:100 B:132 63.0 0.315 S -62.8 -46.5 NA NA NA
2zem 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 52.0 0.26 S -52.7 -44.3 52.0 0.26 0.0 HOH
 2.661
 NZ
 O
LYS B:100 B:132 66.0 0.33 S -51.0 -44.5 NA NA NA
2zen 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 50.0 0.25 S -71.3 -38.3 50.0 0.25 0.0 HOH
 2.878
 O
 O
LYS B:100 B:132 67.0 0.335 S -60.2 -46.1 NA NA NA
2zel 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 53.0 0.265 S -63.9 -39.7 53.0 0.265 0.0 HOH
 2.909
 O
 O
LYS B:100 B:132 67.0 0.335 S -59.9 -45.6 NA NA NA
2zeg 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 48.0 0.24 S -59.1 -43.3 48.0 0.24 0.0 HOH
 2.806
 O
 O
LYS B:100 B:132 62.0 0.31 S -53.2 -45.7 NA NA NA
2zep 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 LYS A:100 A:132 49.0 0.245 S -59.4 -44.9 49.0 0.245 0.0 HOH
 2.674
 O
 O
LYS B:100 B:132 69.0 0.345 S -52.9 -54.2 NA NA NA
7cm0 1 Q16769 100.0 0.0 X-RAY
 2021-12-22 LYS A:98 A:132 61.0 0.305 S -66.2 -41.0 61.0 0.305 0.0 HOH
 7.895
 CE
 O
LYS B:98 B:132 59.0 0.295 S -66.5 -40.1 NA NA NA
LYS C:98 C:132 57.0 0.285 S -66.4 -40.9 NA NA NA
LYS D:98 D:132 60.0 0.3 S -68.1 -42.3 NA NA NA
2afs 1 Q16769 99.7 0.0 X-RAY
 2005-08-23 LYS A:100 A:132 49.0 0.245 S -55.5 -43.7 49.0 0.245 0.0 HOH
 2.672
 O
 O
LYS B:100 B:132 70.0 0.35 S -40.2 -47.3 NA NA NA
6yi1 1 Q16769 100.0 0.0 X-RAY
 2020-07-01 LYS A:100 A:132 61.0 0.305 S -60.9 -42.1 61.0 0.305 0.0 SO4
SO4
GOL
HOH
 7.448
7.182
2.830
2.988
 N
CD
O
N
 O3
O2
O3
O
LYS B:100 B:132 82.0 0.41 S -56.3 -47.6 NA NA NA
6yjy 1 Q16769 100.0 0.0 X-RAY
 2020-07-01 LYS A:100 A:132 65.0 0.325 S -63.2 -37.6 65.0 0.325 0.0 SO4
SO4
HOH
 7.489
7.079
2.868
 N
CD
O
 O4
O2
O
LYS B:100 B:132 85.0 0.425 S -63.0 -41.5 NA NA NA
4yu9 1 Q16769 99.39 0.0 X-RAY
 2015-08-05 LYS A:100 A:132 47.0 0.235 S -59.2 -38.1 47.0 0.235 0.0 EDO
EDO
HOH
 5.608
6.252
2.804
 CD
N
O
 O2
O1
O
LYS B:100 B:132 50.0 0.25 S -63.5 -36.3 NA NA NA
LYS C:100 C:132 49.0 0.245 S -61.2 -36.7 NA NA NA
6gbx 1 Q16769 99.39 0.0 X-RAY
 2018-09-19 LYS A:100 A:132 52.0 0.26 S -67.6 -36.3 52.0 0.26 0.0 EDO
EDO
HOH
 5.623
6.261
2.648
 O
N
NZ
 C2
O1
O
LYS B:100 B:132 50.0 0.25 S -67.2 -37.7 NA NA NA
LYS C:100 C:132 50.0 0.25 S -68.5 -36.0 NA NA NA
7d8e 1 Q16769 99.39 0.0 X-RAY
 2021-12-08 LYS A:100 A:132 79.0 0.395 S -63.0 -37.3 79.0 0.395 0.0 EDO
SO4
HOH
 7.711
9.364
2.833
 N
CB
O
 O2
O3
O
LYS B:100 B:132 81.0 0.405 S -60.4 -37.7 NA NA NA
LYS C:100 C:132 82.0 0.41 S -68.9 -17.0 NA NA NA
7coz 1 Q16769 99.39 0.0 X-RAY
 2021-01-13 LYS A:98 A:132 50.0 0.25 S -64.3 -32.5 50.0 0.25 0.0 EDO
EDO
HOH
 6.312
3.071
2.841
 N
NZ
NZ
 C1
C2
O
LYS B:98 B:132 52.0 0.26 S -63.8 -35.3 NA NA NA
LYS C:98 C:132 48.0 0.24 S -66.1 -33.6 NA NA NA
7cp0 1 Q16769 99.39 0.0 X-RAY
 2021-01-13 LYS A:98 A:132 51.0 0.255 S -66.8 -35.9 51.0 0.255 0.0 EDO
EDO
EDO
HOH
 5.872
5.799
5.122
2.839
 O
N
N
O
 C2
O1
O1
O
LYS B:98 B:132 52.0 0.26 S -66.7 -33.1 NA NA NA
LYS C:98 C:132 52.0 0.26 S -67.4 -35.0 NA NA NA
3si0 1 Q16769 100.0 0.0 X-RAY
 2011-06-29 LYS A:101 A:132 66.0 0.33 S -70.2 -49.1 66.0 0.33 0.0 HOH
 2.870
 O
 O
3si2 1 B2RX76 86.24 0.0 X-RAY
 2011-06-29 LYS A:98 A:133 48.0 0.24 S -60.8 -39.2 48.0 0.24 0.0 ACT
HOH
 7.367
2.603
 CD
NZ
 CH3
O
3si1 1 Q9CYK2 85.93 0.0 X-RAY
 2011-06-29 LYS A:98 A:133 40.0 0.2 -141.7 40.3 40.0 0.2 0.0 HOH
 8.194
 CE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16769-f1 1 Q16769 100.0 0.0 LYS A:132 A:132 46.0 0.23 S -61.2 -38.1