Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 37594447 | . | T | A | CCDS1790.1:NM_012413.3:c.619Tgg>Agg_NP_036545.1:p.207W>R | Homo sapiens glutaminyl-peptide cyclotransferase (QPCT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4ywy | 1 | Q16769 | 99.45 | 0.0 |
X-RAY |
2015-08-05 | TRP | A:207 | A:207 | 98.0 | 0.384 | -58.5 | 126.7 | 98.0 | 0.384 | 0.0 |
ZN PBD EDO HOH |
5.914 3.481 3.178 2.777 |
CZ3 CH2 N O |
ZN CAL C2 O |
|||
| TRP | B:207 | B:207 | 95.0 | 0.373 | -60.4 | 133.5 | NA | NA | NA | ||||||||||||||
| TRP | C:207 | C:207 | 98.0 | 0.384 | -53.3 | 126.2 | NA | NA | NA | ||||||||||||||
| 2afm | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 131.0 | 0.514 | -45.8 | 134.9 | 131.0 | 0.514 | 0.0 |
ZN SO4 HOH |
9.349 2.759 3.959 |
CB N CD1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 99.0 | 0.388 | -54.6 | 117.9 | NA | NA | NA | ||||||||||||||
| 2afo | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 128.0 | 0.502 | -43.9 | 137.1 | 128.0 | 0.502 | 0.0 |
ZN SO4 HOH |
9.282 2.643 3.862 |
CB N CD1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 96.0 | 0.376 | -53.7 | 134.6 | NA | NA | NA | ||||||||||||||
| 2afw | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 138.0 | 0.541 | -45.1 | 140.9 | 138.0 | 0.541 | 0.0 |
ZN SO4 AHN HOH |
9.088 2.559 5.800 2.512 |
CB N CD1 NE1 |
ZN O3 N O |
|||
| TRP | B:175 | B:207 | 87.0 | 0.341 | -50.4 | 114.8 | NA | NA | NA | ||||||||||||||
| 2afx | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 131.0 | 0.514 | -48.3 | 137.1 | 131.0 | 0.514 | 0.0 |
ZN SO4 1BN HOH |
8.855 2.801 3.964 2.543 |
CB CB CD1 CZ2 |
ZN O3 C7 O |
|||
| TRP | B:175 | B:207 | 97.0 | 0.38 | -57.5 | 120.3 | NA | NA | NA | ||||||||||||||
| 2afz | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 133.0 | 0.522 | -44.7 | 137.9 | 133.0 | 0.522 | 0.0 |
ZN SO4 NVI HOH |
9.127 2.702 7.012 2.540 |
CB N CD1 NE1 |
ZN O3 C5 O |
|||
| TRP | B:175 | B:207 | 100.0 | 0.392 | -55.7 | 119.6 | NA | NA | NA | ||||||||||||||
| 3pbb | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2011-02-02 | TRP | A:175 | A:207 | 92.0 | 0.361 | -50.1 | 115.6 | 92.0 | 0.361 | 0.0 |
PBD ZN HOH |
3.448 6.467 2.693 |
CH2 CZ3 O |
CAL ZN O |
|||
| TRP | B:175 | B:207 | 90.0 | 0.353 | -55.1 | 116.6 | NA | NA | NA | ||||||||||||||
| 2zef | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 136.0 | 0.533 | -45.5 | 136.0 | 136.0 | 0.533 | 0.0 |
ZN SO4 HOH |
9.100 2.706 2.450 |
CB N NE1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 91.0 | 0.357 | -53.2 | 131.1 | NA | NA | NA | ||||||||||||||
| 2zed | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 132.0 | 0.518 | -47.4 | 134.0 | 132.0 | 0.518 | 0.0 |
ZN SO4 HOH |
9.307 2.816 3.815 |
CB N CE3 |
ZN O3 O |
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| TRP | B:175 | B:207 | 94.0 | 0.369 | -56.1 | 115.5 | NA | NA | NA | ||||||||||||||
| 2afu | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 118.0 | 0.463 | -38.4 | 137.8 | 118.0 | 0.463 | 0.0 |
ZN BGT HOH |
9.072 3.527 3.544 |
CB CD1 N |
ZN C3 O |
|||
| TRP | B:175 | B:207 | 53.0 | 0.208 | -49.6 | 118.4 | NA | NA | NA | ||||||||||||||
| 2zeh | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 128.0 | 0.502 | -45.7 | 134.1 | 128.0 | 0.502 | 0.0 |
ZN SO4 HOH |
9.025 2.797 3.855 |
CB N CD1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 96.0 | 0.376 | -55.7 | 119.4 | NA | NA | NA | ||||||||||||||
| 2zeo | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 133.0 | 0.522 | -48.9 | 135.7 | 133.0 | 0.522 | 0.0 |
ZN SO4 HOH |
9.357 2.698 4.072 |
CB N NE1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 82.0 | 0.322 | -52.4 | 127.0 | NA | NA | NA | ||||||||||||||
| 2zee | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 130.0 | 0.51 | -46.7 | 134.9 | 130.0 | 0.51 | 0.0 |
ZN SO4 HOH |
9.342 2.713 2.947 |
CB N NE1 |
ZN O3 O |
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| TRP | B:175 | B:207 | 86.0 | 0.337 | -56.7 | 117.8 | NA | NA | NA | ||||||||||||||
| 3pbe | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2011-02-02 | PHE | A:175 | A:207 | 77.0 | 0.367 | -49.2 | 128.4 | 77.0 | 0.367 | 0.0 |
ZN SO4 HOH |
6.282 2.750 3.241 |
CE1 N CE1 |
ZN O3 O |
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| PHE | B:175 | B:207 | 86.0 | 0.41 | -65.4 | 112.4 | NA | NA | NA | ||||||||||||||
| 2zem | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 133.0 | 0.522 | -50.3 | 135.4 | 133.0 | 0.522 | 0.0 |
ZN SO4 HOH |
9.144 2.509 3.586 |
CB N CD1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 90.0 | 0.353 | -55.6 | 118.2 | NA | NA | NA | ||||||||||||||
| 2zen | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 129.0 | 0.506 | -46.7 | 135.5 | 129.0 | 0.506 | 0.0 |
ZN SO4 HOH |
9.141 2.711 4.057 |
CB N CD1 |
ZN O3 O |
|||
| TRP | B:175 | B:207 | 87.0 | 0.341 | -54.3 | 118.1 | NA | NA | NA | ||||||||||||||
| 2zel | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 130.0 | 0.51 | -51.3 | 132.1 | 130.0 | 0.51 | 0.0 |
ZN SO4 HOH |
9.045 2.877 3.910 |
CB N CD1 |
ZN O3 O |
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| TRP | B:175 | B:207 | 92.0 | 0.361 | -58.4 | 119.0 | NA | NA | NA | ||||||||||||||
| 2zeg | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 94.0 | 0.369 | -52.8 | 130.6 | 94.0 | 0.369 | 0.0 |
ZN SO4 IMD HOH |
5.941 2.952 4.146 3.169 |
CZ3 N CZ3 CE3 |
ZN O3 C2 O |
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| TRP | B:175 | B:207 | 96.0 | 0.376 | -51.8 | 121.0 | NA | NA | NA | ||||||||||||||
| 2zep | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2008-04-22 | TRP | A:175 | A:207 | 128.0 | 0.502 | -47.4 | 135.8 | 128.0 | 0.502 | 0.0 |
ZN SO4 HOH |
9.351 2.717 3.954 |
CB N CD1 |
ZN O3 O |
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| TRP | B:175 | B:207 | 81.0 | 0.318 | -55.8 | 130.3 | NA | NA | NA | ||||||||||||||
| 7cm0 | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2021-12-22 | TRP | A:173 | A:207 | 101.0 | 0.396 | -70.3 | 123.8 | 101.0 | 0.396 | 0.0 |
G5R ZN HOH |
4.328 6.444 8.404 |
NE1 CZ3 CH2 |
C15 ZN O |
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| TRP | B:173 | B:207 | 110.0 | 0.431 | -68.8 | 119.0 | NA | NA | NA | ||||||||||||||
| TRP | C:173 | C:207 | 107.0 | 0.42 | -70.4 | 121.0 | NA | NA | NA | ||||||||||||||
| TRP | D:173 | D:207 | 103.0 | 0.404 | -67.9 | 122.4 | NA | NA | NA | ||||||||||||||
| 2afs | 1 | Q16769 | 99.7 | 0.0 |
X-RAY |
2005-08-23 | TRP | A:175 | A:207 | 130.0 | 0.51 | -48.8 | 135.8 | 130.0 | 0.51 | 0.0 |
ZN SO4 HOH |
9.315 2.809 3.623 |
CB N CD1 |
ZN O3 O |
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| TRP | B:175 | B:207 | 92.0 | 0.361 | -55.8 | 123.9 | NA | NA | NA | ||||||||||||||
| 6yi1 | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2020-07-01 | TRP | A:175 | A:207 | 69.0 | 0.271 | -52.1 | 120.6 | 69.0 | 0.271 | 0.0 |
ZN ORT PHE 66N HOH |
6.858 3.403 3.430 6.327 2.693 |
CZ3 CH2 NE1 NE1 O |
ZN N4 CB N11 O |
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| TRP | B:175 | B:207 | 47.0 | 0.184 | -53.9 | 125.8 | NA | NA | NA | ||||||||||||||
| 6yjy | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2020-07-01 | TRP | A:175 | A:207 | 135.0 | 0.529 | -53.6 | 138.7 | 135.0 | 0.529 | 0.0 |
SO4 LEU HOH |
2.959 3.451 4.164 |
N CE3 C |
O3 CD2 O |
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| TRP | B:175 | B:207 | 48.0 | 0.188 | -57.7 | 123.7 | NA | NA | NA | ||||||||||||||
| 4yu9 | 1 | Q16769 | 99.39 | 0.0 |
X-RAY |
2015-08-05 | TRP | A:175 | A:207 | 100.0 | 0.392 | -62.4 | 131.9 | 100.0 | 0.392 | 0.0 |
ZN HOH |
6.281 2.971 |
CZ3 NE1 |
ZN O |
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| TRP | B:175 | B:207 | 97.0 | 0.38 | -61.8 | 130.6 | NA | NA | NA | ||||||||||||||
| TRP | C:175 | C:207 | 96.0 | 0.376 | -51.1 | 134.7 | NA | NA | NA | ||||||||||||||
| 6gbx | 1 | Q16769 | 99.39 | 0.0 |
X-RAY |
2018-09-19 | TRP | A:175 | A:207 | 98.0 | 0.384 | -50.5 | 128.2 | 98.0 | 0.384 | 0.0 |
ZN S77 HOH |
6.266 3.288 2.783 |
CZ3 CB O |
ZN C12 O |
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| TRP | B:175 | B:207 | 100.0 | 0.392 | -53.6 | 127.4 | NA | NA | NA | ||||||||||||||
| TRP | C:175 | C:207 | 101.0 | 0.396 | -55.8 | 128.3 | NA | NA | NA | ||||||||||||||
| 7d8e | 1 | Q16769 | 99.39 | 0.0 |
X-RAY |
2021-12-08 | TRP | A:175 | A:207 | 112.0 | 0.439 | -53.0 | 118.5 | 112.0 | 0.439 | 0.0 |
ZN GYO HOH |
6.394 3.162 3.680 |
CZ3 CE3 CE3 |
ZN C15 O |
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| TRP | B:175 | B:207 | 113.0 | 0.443 | -52.9 | 126.4 | NA | NA | NA | ||||||||||||||
| TRP | C:175 | C:207 | 115.0 | 0.451 | -54.1 | 117.7 | NA | NA | NA | ||||||||||||||
| 7coz | 1 | Q16769 | 99.39 | 0.0 |
X-RAY |
2021-01-13 | TRP | A:173 | A:207 | 105.0 | 0.412 | -52.6 | 126.3 | 105.0 | 0.412 | 0.0 |
ZN Q39 EDO HOH |
6.511 3.257 3.133 2.995 |
CZ3 CH2 N NE1 |
ZN C4 O1 O |
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| TRP | B:173 | B:207 | 103.0 | 0.404 | -54.4 | 127.5 | NA | NA | NA | ||||||||||||||
| TRP | C:173 | C:207 | 104.0 | 0.408 | -58.3 | 128.2 | NA | NA | NA | ||||||||||||||
| 7cp0 | 1 | Q16769 | 99.39 | 0.0 |
X-RAY |
2021-01-13 | TRP | A:173 | A:207 | 102.0 | 0.4 | -55.6 | 127.0 | 102.0 | 0.4 | 0.0 |
ZN EDO HOH |
6.389 3.723 2.946 |
CZ3 CE3 NE1 |
ZN O2 O |
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| TRP | B:173 | B:207 | 101.0 | 0.396 | -48.1 | 130.5 | NA | NA | NA | ||||||||||||||
| TRP | C:173 | C:207 | 99.0 | 0.388 | -53.8 | 129.3 | NA | NA | NA | ||||||||||||||
| 3si0 | 1 | Q16769 | 100.0 | 0.0 |
X-RAY |
2011-06-29 | TRP | A:176 | A:207 | 80.0 | 0.314 | -68.9 | 111.8 | 80.0 | 0.314 | 0.0 |
ZN IMD HOH |
6.126 3.987 2.755 |
CZ3 CZ3 O |
ZN C2 O |
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| 3si2 | 1 | B2RX76 | 86.24 | 0.0 |
X-RAY |
2011-06-29 | TRP | A:173 | A:208 | 81.0 | 0.318 | -57.6 | 129.1 | 81.0 | 0.318 | 0.0 |
ZN PBD HOH |
6.016 3.453 2.917 |
CZ3 CH2 NE1 |
ZN CAL O |
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| 3si1 | 1 | Q9CYK2 | 85.93 | 0.0 |
X-RAY |
2011-06-29 | TRP | A:173 | A:208 | 109.0 | 0.427 | -50.1 | 125.2 | 109.0 | 0.427 | 0.0 |
ZN HOH |
6.347 3.515 |
CZ3 CZ3 |
ZN O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q16769-f1 | 1 | Q16769 | 100.0 | 0.0 | TRP | A:207 | A:207 | 88.0 | 0.345 | -50.0 | 116.4 | ||