Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 37594498 . G A CCDS1790.1:NM_012413.3:c.670Gca>Aca_NP_036545.1:p.224A>T Homo sapiens glutaminyl-peptide cyclotransferase (QPCT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ywy 1 Q16769 99.45 0.0 X-RAY
 2015-08-05 ALA A:224 A:224 36.0 0.313 H -58.6 -31.3 36.0 0.313 0.0 EDO
EDO
EDO
SO4
HOH
 6.202
8.421
6.563
9.857
3.434
 CB
N
N
CB
O
 O1
O1
O1
O4
O
ALA B:224 B:224 37.0 0.322 H -53.1 -36.8 NA NA NA
ALA C:224 C:224 37.0 0.322 H -56.7 -34.6 NA NA NA
2afm 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 40.0 0.348 H -65.7 -24.3 40.0 0.348 0.0 HOH
 3.141
 O
 O
ALA B:192 B:224 37.0 0.322 H -68.1 -19.9 NA NA NA
2afo 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 37.0 0.322 H -70.3 -22.4 37.0 0.322 0.0 HOH
 3.296
 O
 O
ALA B:192 B:224 38.0 0.33 H -66.3 -25.4 NA NA NA
2afw 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 39.0 0.339 H -66.4 -24.2 39.0 0.339 0.0 HOH
 3.175
 O
 O
ALA B:192 B:224 38.0 0.33 H -69.6 -20.1 NA NA NA
2afx 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 38.0 0.33 H -66.9 -25.8 38.0 0.33 0.0 HOH
 3.115
 O
 O
ALA B:192 B:224 37.0 0.322 H -69.6 -20.8 NA NA NA
2afz 1 Q16769 100.0 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 40.0 0.348 H -65.2 -26.3 40.0 0.348 0.0 HOH
 3.258
 O
 O
ALA B:192 B:224 37.0 0.322 H -66.8 -21.8 NA NA NA
3pbb 1 Q16769 100.0 0.0 X-RAY
 2011-02-02 ALA A:192 A:224 38.0 0.33 H -63.3 -30.4 38.0 0.33 0.0 HOH
 2.875
 O
 O
ALA B:192 B:224 40.0 0.348 H -56.2 -21.2 NA NA NA
2zef 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 40.0 0.348 H -67.7 -23.6 40.0 0.348 0.0 HOH
 3.317
 O
 O
ALA B:192 B:224 38.0 0.33 H -69.9 -18.2 NA NA NA
2zed 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 41.0 0.357 H -67.0 -25.4 41.0 0.357 0.0 HOH
 3.570
 O
 O
ALA B:192 B:224 39.0 0.339 H -66.8 -17.6 NA NA NA
2afu 1 Q16769 99.7 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 37.0 0.322 H -65.6 -25.0 37.0 0.322 0.0 HOH
 4.101
 O
 O
ALA B:192 B:224 37.0 0.322 H -65.2 -26.0 NA NA NA
2zeh 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 38.0 0.33 H -63.1 -27.5 38.0 0.33 0.0 HOH
 3.389
 O
 O
ALA B:192 B:224 38.0 0.33 H -69.3 -18.4 NA NA NA
2zeo 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 41.0 0.357 H -64.8 -27.4 41.0 0.357 0.0 HOH
 3.077
 O
 O
ALA B:192 B:224 39.0 0.339 H -67.7 -20.5 NA NA NA
2zee 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 40.0 0.348 H -64.2 -26.3 40.0 0.348 0.0 HOH
 3.383
 O
 O
ALA B:192 B:224 39.0 0.339 H -67.5 -14.2 NA NA NA
3pbe 1 Q16769 99.7 0.0 X-RAY
 2011-02-02 ALA A:192 A:224 40.0 0.348 H -64.9 -24.0 40.0 0.348 0.0 HOH
 3.362
 O
 O
ALA B:192 B:224 39.0 0.339 H -63.9 -17.4 NA NA NA
2zem 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 39.0 0.339 H -70.3 -21.5 39.0 0.339 0.0 HOH
 3.720
 O
 O
ALA B:192 B:224 41.0 0.357 H -63.5 -18.1 NA NA NA
2zen 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 41.0 0.357 H -66.9 -22.0 41.0 0.357 0.0 HOH
 3.282
 O
 O
ALA B:192 B:224 38.0 0.33 H -69.0 -20.1 NA NA NA
2zel 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 39.0 0.339 H -66.5 -23.8 39.0 0.339 0.0 HOH
 3.629
 O
 O
ALA B:192 B:224 38.0 0.33 H -64.4 -16.3 NA NA NA
2zeg 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 39.0 0.339 H -67.3 -21.1 39.0 0.339 0.0 HOH
 3.850
 O
 O
ALA B:192 B:224 37.0 0.322 H -63.0 -18.0 NA NA NA
2zep 1 Q16769 99.7 0.0 X-RAY
 2008-04-22 ALA A:192 A:224 42.0 0.365 H -67.4 -21.6 42.0 0.365 0.0 HOH
 3.334
 O
 O
ALA B:192 B:224 38.0 0.33 H -67.1 -20.2 NA NA NA
7cm0 1 Q16769 100.0 0.0 X-RAY
 2021-12-22 ALA A:190 A:224 38.0 0.33 H -68.4 -15.8 38.0 0.33 0.0 HOH
 6.369
 C
 O
ALA B:190 B:224 28.0 0.243 H -71.7 -10.3 NA NA NA
ALA C:190 C:224 28.0 0.243 H -72.7 -23.1 NA NA NA
ALA D:190 D:224 34.0 0.296 H -70.6 -19.3 NA NA NA
2afs 1 Q16769 99.7 0.0 X-RAY
 2005-08-23 ALA A:192 A:224 38.0 0.33 H -69.0 -22.2 38.0 0.33 0.0 HOH
 3.611
 O
 O
ALA B:192 B:224 39.0 0.339 H -65.1 -18.8 NA NA NA
6yi1 1 Q16769 100.0 0.0 X-RAY
 2020-07-01 ALA A:192 A:224 38.0 0.33 H -61.9 -25.2 38.0 0.33 0.0 GOL
HOH
 9.111
2.911
 N
O
 C2
O
ALA B:192 B:224 38.0 0.33 H -67.7 -22.6 NA NA NA
6yjy 1 Q16769 100.0 0.0 X-RAY
 2020-07-01 ALA A:192 A:224 40.0 0.348 H -64.3 -26.0 40.0 0.348 0.0 HOH
 3.019
 O
 O
ALA B:192 B:224 38.0 0.33 H -67.3 -20.4 NA NA NA
4yu9 1 Q16769 99.39 0.0 X-RAY
 2015-08-05 ALA A:192 A:224 37.0 0.322 H -66.7 -31.1 37.0 0.322 0.0 SO4
SO4
EDO
HOH
 6.506
9.638
5.999
3.414
 CB
CB
CB
O
 O4
O4
O1
O
ALA B:192 B:224 35.0 0.304 H -61.4 -34.4 NA NA NA
ALA C:192 C:224 35.0 0.304 H -59.1 -32.9 NA NA NA
6gbx 1 Q16769 99.39 0.0 X-RAY
 2018-09-19 ALA A:192 A:224 37.0 0.322 H -63.1 -30.5 37.0 0.322 0.0 SO4
EDO
EDO
HOH
 9.876
8.644
6.293
2.649
 CB
N
CB
O
 O1
O1
O2
O
ALA B:192 B:224 37.0 0.322 H -60.8 -32.0 NA NA NA
ALA C:192 C:224 38.0 0.33 H -61.3 -31.0 NA NA NA
7d8e 1 Q16769 99.39 0.0 X-RAY
 2021-12-08 ALA A:192 A:224 38.0 0.33 H -64.0 -28.6 38.0 0.33 0.0 EDO
SO4
HOH
 6.316
9.838
3.525
 CB
CB
O
 O2
O3
O
ALA B:192 B:224 36.0 0.313 H -66.9 -28.3 NA NA NA
ALA C:192 C:224 39.0 0.339 H -63.3 -29.2 NA NA NA
7coz 1 Q16769 99.39 0.0 X-RAY
 2021-01-13 ALA A:190 A:224 37.0 0.322 H -59.2 -31.9 37.0 0.322 0.0 SO4
EDO
HOH
 9.638
6.803
3.503
 CB
N
O
 O4
O1
O
ALA B:190 B:224 33.0 0.287 H -61.8 -30.0 NA NA NA
ALA C:190 C:224 35.0 0.304 H -62.2 -30.2 NA NA NA
7cp0 1 Q16769 99.39 0.0 X-RAY
 2021-01-13 ALA A:190 A:224 36.0 0.313 H -60.5 -31.5 36.0 0.313 0.0 SO4
EDO
EDO
HOH
 9.703
8.535
6.086
3.346
 CB
N
CB
O
 O2
O1
O1
O
ALA B:190 B:224 37.0 0.322 H -56.3 -33.5 NA NA NA
ALA C:190 C:224 35.0 0.304 H -58.5 -31.7 NA NA NA
3si0 1 Q16769 100.0 0.0 X-RAY
 2011-06-29 ALA A:193 A:224 39.0 0.339 H -82.2 -21.4 39.0 0.339 0.0 HOH
 2.915
 O
 O
3si2 1 B2RX76 86.24 0.0 X-RAY
 2011-06-29 ALA A:190 A:225 23.0 0.2 H -70.6 -29.2 23.0 0.2 0.0 HOH
 3.589
 CB
 O
3si1 1 Q9CYK2 85.93 0.0 X-RAY
 2011-06-29 ALA A:190 A:225 20.0 0.174 H -60.3 -51.6 20.0 0.174 0.0 HOH
 9.251
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16769-f1 1 Q16769 100.0 0.0 ALA A:224 A:224 40.0 0.348 H -64.0 -34.3