Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 61717842 | . | A | C | CCDS33205.1:NM_003400.3:c.1957Ttg>Gtg_NP_003391.1:p.653L>V | Homo sapiens exportin 1 (XPO1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3gb8 | 1 | O14980 | 100.0 | 0.0 |
X-RAY |
2009-03-31 | LEU | A:653 | A:653 | 6.0 | 0.035 | H | -58.7 | -51.1 | 6.0 | 0.035 | 0.0 | ||||||
3gjx | 3 | Q6P5F9 | 98.04 | 0.0 |
X-RAY |
2009-05-26 | LEU | C:655 | A:653 | 15.0 | 0.088 | H | -55.4 | -44.1 | 15.0 | 0.088 | 0.0 |
HOH |
3.004 |
CD1 |
O |
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LEU | F:655 | D:653 | 14.0 | 0.082 | H | -60.1 | -42.8 | NA | NA | NA | |||||||||||||
3nby | 3 | Q6P5F9 | 98.04 | 0.0 |
X-RAY |
2010-10-27 | LEU | C:655 | A:653 | 7.0 | 0.041 | H | -61.9 | -35.3 | 7.0 | 0.041 | 0.0 | ||||||
LEU | F:655 | D:653 | 11.0 | 0.065 | H | -61.6 | -38.3 | NA | NA | NA | |||||||||||||
3nbz | 1 | Q6P5F9 | 98.04 | 0.0 |
X-RAY |
2010-10-27 | LEU | A:655 | A:653 | 17.0 | 0.1 | H | -69.6 | -43.7 | 17.0 | 0.1 | 0.0 |
HOH |
3.759 |
CD1 |
O |
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LEU | D:655 | D:653 | 16.0 | 0.094 | H | -66.0 | -42.5 | NA | NA | NA | |||||||||||||
3nc0 | 1 | Q6P5F9 | 98.04 | 0.0 |
X-RAY |
2010-10-27 | LEU | A:655 | A:653 | 14.0 | 0.082 | H | -55.9 | -44.1 | 14.0 | 0.082 | 0.0 |
PEG HOH |
9.428 7.714 |
N O |
O4 O |
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LEU | D:655 | D:653 | 13.0 | 0.076 | H | -57.4 | -43.3 | 13.0 | 0.076 | 0.0 |
HOH |
6.577 |
N |
O |
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3nc1 | 2 | Q6P5F9 | 98.04 | 0.0 |
X-RAY |
2010-10-27 | LEU | B:655 | A:653 | 10.0 | 0.059 | H | -69.2 | -10.6 | 10.0 | 0.059 | 0.0 | ||||||
5dis | 1 | O14980 | 100.0 | 0.0 |
X-RAY |
2015-11-04 | LEU | A:649 | A:653 | 10.0 | 0.059 | H | -60.5 | -46.0 | 10.0 | 0.059 | 0.0 | ||||||
6tvo | 2 | O14980 | 99.71 | 0.0 |
X-RAY |
2020-07-08 | LEU | B:667 | A:653 | 9.0 | 0.053 | H | -60.8 | -43.4 | 9.0 | 0.053 | 0.0 | ||||||
7b51 | 2 | O14980 | 99.71 | 0.0 |
X-RAY |
2021-03-10 | LEU | B:667 | A:653 | 11.0 | 0.065 | H | -53.9 | -50.4 | 11.0 | 0.065 | 0.0 |
HOH |
7.165 |
O |
O |
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4bsm | 1 | O14980 | 100.0 | 0.0 |
X-RAY |
2013-07-31 | LEU | A:653 | A:653 | 28.0 | 0.165 | H | -66.2 | -34.4 | 28.0 | 0.165 | 0.0 | ||||||
4bsn | 1 | O14980 | 100.0 | 0.0 |
X-RAY |
2013-07-31 | LEU | A:653 | A:653 | 28.0 | 0.165 | H | -74.2 | -35.6 | 28.0 | 0.165 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-o14980-f1 | 1 | O14980 | 100.0 | 0.0 | LEU | A:653 | A:653 | 10.0 | 0.059 | H | -63.9 | -41.7 |