Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 98264555 . A C CCDS2032.1:NM_001862.2:c.374cAg>cCg_NP_001853.2:p.125Q>P Homo sapiens cytochrome c oxidase subunit 5B (COX5B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2y69 6 P00428 82.95 1e-81 X-RAY
 2011-02-23 HIS F:125 F:94 86.0 0.441 86.3 121.5 86.0 0.441 0.0 HOH
 2.751
 O
 O
HIS S:125 S:94 98.0 0.503 107.9 -175.1 NA NA NA
5z62 6 P10606 100.0 3e-71 EM
 2019-02-27 GLN F:94 F:125 78.0 0.433 -121.4 125.4 78.0 0.433 0.0
7o37 18 P19536 85.86 2e-64 EM
 2021-10-13 HIS BA:95 f:95 154.0 0.79 -137.2 -2.2 154.0 0.79 0.0
7o3c 18 P19536 85.86 2e-64 EM
 2021-10-13 HIS BA:95 f:95 135.0 0.692 -129.9 21.5 135.0 0.692 0.0
7o3e 16 P19536 85.86 2e-64 EM
 2021-10-13 HIS V:95 f:95 158.0 0.81 -142.8 2.4 158.0 0.81 0.0
5j4z 67 W5PW27 86.73 2e-64 EM
 2016-09-21 HIS DC:94 BP:94 61.0 NA S 50.4 -135.8 61.0 NA NA
5j7y 67 W5PW27 86.73 2e-64 EM
 2016-09-21 HIS DC:94 BP:94 60.0 NA S 50.4 -135.8 60.0 NA NA
1occ 6 P00428 85.71 5e-64 X-RAY
 1996-12-07 HIS F:94 F:94 37.0 0.19 -81.7 114.5 24.0 0.123 0.067 A:P00396:0.031
C:P00415:0.051
HIS S:94 S:94 40.0 0.205 -81.8 114.5 25.0 0.128 0.077 N:P00396:0.041
P:P00415:0.062
1oco 6 P00428 85.71 5e-64 X-RAY
 1999-07-22 HIS F:94 F:94 36.0 0.185 -74.5 131.9 22.0 0.113 0.072 A:P00396:0.036
C:P00415:0.056
HIS S:94 S:94 37.0 0.19 -73.7 132.1 22.0 0.113 0.077 P:P00415:0.062
N:P00396:0.041
1ocr 6 P00428 85.71 5e-64 X-RAY
 1999-07-29 HIS F:94 F:94 21.0 0.108 -74.5 163.8 9.0 0.046 0.062 A:P00396:0.021
C:P00415:0.051
HIS S:94 S:94 20.0 0.103 -73.2 163.5 8.0 0.041 0.062 N:P00396:0.026
P:P00415:0.056
1ocz 6 P00428 85.71 5e-64 X-RAY
 1999-07-22 HIS F:94 F:94 37.0 0.19 -67.7 164.0 26.0 0.133 0.057 A:P00396:0.031
C:P00415:0.046
HIS S:94 S:94 38.0 0.195 -66.9 165.1 25.0 0.128 0.067 P:P00415:0.051
N:P00396:0.036
1v54 6 P00428 85.71 5e-64 X-RAY
 2003-12-23 HIS F:94 F:94 96.0 0.492 49.4 175.0 96.0 0.492 0.0 HOH
 6.154
 O
 O
HIS S:94 S:94 114.0 0.585 13.2 -169.6 113.0 0.579 0.006 P:P00415:0.005
 HOH
 7.237
 CD2
 O
1v55 6 P00428 85.71 5e-64 X-RAY
 2003-12-23 HIS F:94 F:94 105.0 0.538 49.8 171.5 105.0 0.538 0.0 HOH
 2.723
 O
 O
HIS S:94 S:94 123.0 0.631 15.5 -174.5 123.0 0.631 0.0 HOH
 2.998
 O
 O
2dyr 6 P00428 85.71 5e-64 X-RAY
 2007-04-03 HIS F:94 F:94 95.0 0.487 59.6 173.7 95.0 0.487 0.0 HOH
 5.691
 O
 O
HIS S:94 S:94 106.0 0.544 25.0 -170.7 106.0 0.544 0.0 HOH
 7.222
 O
 O
2dys 6 P00428 85.71 5e-64 X-RAY
 2007-04-03 HIS F:94 F:94 102.0 0.523 48.8 175.4 102.0 0.523 0.0 HOH
 2.557
 O
 O
HIS S:94 S:94 122.0 0.626 16.6 -170.0 122.0 0.626 0.0 HOH
 2.936
 N
 O
2eij 6 P00428 85.71 5e-64 X-RAY
 2007-05-29 HIS F:94 F:94 96.0 0.492 51.6 173.5 96.0 0.492 0.0 HOH
 3.497
 O
 O
HIS S:94 S:94 119.0 0.61 16.4 -169.9 119.0 0.61 0.0 HOH
 2.900
 O
 O
2eik 6 P00428 85.71 5e-64 X-RAY
 2007-05-29 HIS F:94 F:94 94.0 0.482 54.5 170.4 94.0 0.482 0.0 HOH
 2.657
 O
 O
HIS S:94 S:94 124.0 0.636 24.2 -176.9 124.0 0.636 0.0 HOH
 2.841
 O
 O
2eil 6 P00428 85.71 5e-64 X-RAY
 2007-05-29 HIS F:94 F:94 94.0 0.482 51.9 177.3 94.0 0.482 0.0 HOH
 2.718
 O
 O
HIS S:94 S:94 118.0 0.605 16.3 -167.2 118.0 0.605 0.0 HOH
 2.593
 O
 O
2eim 6 P00428 85.71 5e-64 X-RAY
 2007-05-29 HIS F:94 F:94 94.0 0.482 47.9 173.4 94.0 0.482 0.0 HOH
 3.694
 CB
 O
HIS S:94 S:94 127.0 0.651 21.7 -174.3 127.0 0.651 0.0 HOH
 2.885
 O
 O
2ein 6 P00428 85.71 5e-64 X-RAY
 2007-05-29 HIS F:94 F:94 94.0 0.482 29.5 -178.2 94.0 0.482 0.0 HOH
 7.221
 O
 O
HIS S:94 S:94 131.0 0.672 10.5 -169.5 131.0 0.672 0.0 HOH
 4.000
 NE2
 O
2occ 6 P00428 85.71 5e-64 X-RAY
 1999-01-13 HIS F:94 F:94 41.0 0.21 -86.5 179.8 29.0 0.149 0.061 A:P00396:0.026
C:P00415:0.046
HIS S:94 S:94 40.0 0.205 -84.8 179.9 NA NA NA
2ybb 25 P00428 85.71 5e-64 EM
 2011-10-19 HIS Y:94 Q:94 38.0 0.195 -81.7 114.5 24.0 0.123 0.072 V:P00415:0.056
T:P00396:0.036
2zxw 6 P00428 85.71 5e-64 X-RAY
 2009-02-24 HIS F:94 F:94 99.0 0.508 89.1 159.2 99.0 0.508 0.0 HOH
 2.445
 O
 O
HIS S:94 S:94 103.0 0.528 81.4 -174.5 NA NA NA
3abk 6 P00428 85.71 5e-64 X-RAY
 2010-03-09 HIS F:94 F:94 90.0 0.462 140.8 160.7 90.0 0.462 0.0 HOH
 3.025
 N
 O
HIS S:94 S:94 101.0 0.518 102.9 175.8 NA NA NA
3abl 6 P00428 85.71 5e-64 X-RAY
 2010-01-19 HIS F:94 F:94 103.0 0.528 86.9 135.6 103.0 0.528 0.0 HOH
 2.422
 CE1
 O
HIS S:94 S:94 107.0 0.549 126.8 -148.8 NA NA NA
3abm 6 P00428 85.71 5e-64 X-RAY
 2010-01-19 HIS F:94 F:94 104.0 0.533 59.2 134.6 104.0 0.533 0.0 HOH
 8.048
 C
 O
HIS S:94 S:94 105.0 0.538 125.4 -142.9 NA NA NA
3ag1 6 P00428 85.71 5e-64 X-RAY
 2010-04-28 HIS F:94 F:94 89.0 0.456 135.3 -173.6 89.0 0.456 0.0 HOH
 2.479
 O
 O
HIS S:94 S:94 95.0 0.487 108.4 -172.9 NA NA NA
3ag2 6 P00428 85.71 5e-64 X-RAY
 2010-04-28 HIS F:94 F:94 54.0 0.277 -160.4 166.0 54.0 0.277 0.0 EDO
HOH
 9.901
5.505
 CE1
CE1
 O1
O
HIS S:94 S:94 144.0 0.738 101.4 -128.5 NA NA NA
3ag3 6 P00428 85.71 5e-64 X-RAY
 2010-04-28 HIS F:94 F:94 99.0 0.508 128.8 160.7 99.0 0.508 0.0 HOH
 7.689
 O
 O
HIS S:94 S:94 108.0 0.554 98.8 -179.7 NA NA NA
3ag4 6 P00428 85.71 5e-64 X-RAY
 2010-04-28 HIS F:94 F:94 103.0 0.528 96.2 155.7 103.0 0.528 0.0 HOH
 3.189
 ND1
 O
HIS S:94 S:94 113.0 0.579 118.2 -170.3 NA NA NA
3asn 6 P00428 85.71 5e-64 X-RAY
 2011-08-03 HIS F:94 F:94 96.0 0.492 84.9 153.9 96.0 0.492 0.0 HOH
 2.520
 O
 O
HIS S:94 S:94 105.0 0.538 -30.0 -139.1 NA NA NA
3aso 6 P00428 85.71 5e-64 X-RAY
 2011-08-03 HIS F:94 F:94 93.0 0.477 80.5 155.3 93.0 0.477 0.0 HOH
 2.709
 O
 O
HIS S:94 S:94 108.0 0.554 -34.1 -141.7 NA NA NA
3wg7 6 P00428 85.71 5e-64 X-RAY
 2014-04-30 HIS F:94 F:94 103.0 0.528 110.4 163.7 103.0 0.528 0.0 HOH
 3.117
 O
 O
HIS S:94 S:94 124.0 0.636 105.8 -176.9 NA NA NA
3x2q 6 P00428 85.71 5e-64 X-RAY
 2015-06-10 HIS F:94 F:94 112.0 0.574 102.8 177.4 112.0 0.574 0.0 HOH
 2.303
 O
 O
HIS S:94 S:94 120.0 0.615 117.9 -143.9 NA NA NA
5b1a 6 P00428 85.71 5e-64 X-RAY
 2016-09-14 HIS F:94 F:94 101.0 0.518 135.5 164.8 101.0 0.518 0.0 HOH
 2.535
 CE1
 O
HIS S:94 S:94 116.0 0.595 100.7 -167.5 NA NA NA
5b1b 6 P00428 85.71 5e-64 X-RAY
 2016-09-14 HIS F:94 F:94 90.0 0.462 141.2 163.5 90.0 0.462 0.0 HOH
 2.314
 ND1
 O
HIS S:94 S:94 116.0 0.595 -105.7 -109.2 NA NA NA
5b3s 6 P00428 85.71 5e-64 X-RAY
 2017-03-22 HIS F:94 F:94 187.0 0.959 103.9 360.0 187.0 0.959 0.0 HOH
 2.497
 O
 O
HIS S:94 S:94 206.0 1.0 -29.1 360.0 NA NA NA
5gpn 39 P00428 85.71 5e-64 EM
 2017-04-05 HIS ZA:94 3:94 43.0 NA -81.7 114.4 43.0 NA NA
5gup 65 ? 85.71 5e-64 EM
 2017-03-29 HIS ZB:94 Ap:94 39.0 0.2 -81.5 114.4 25.0 0.128 0.072 WB:None:0.051
UB:None:0.036
5iy5 6 P00428 85.71 5e-64 X-RAY
 2017-01-11 HIS F:94 F:94 68.0 0.349 -45.8 -59.0 68.0 0.349 0.0 HOH
 2.056
 O
 O
HIS S:94 S:94 78.0 0.4 B 47.9 -173.0 NA NA NA
5luf 17 P00428 85.71 5e-64 EM
 2016-11-30 HIS BA:94 3:94 38.0 0.195 -81.7 114.5 24.0 0.123 0.072 W:P00396:0.036
Y:P00415:0.056
5w97 6 P00428 85.71 5e-64 X-RAY
 2017-08-09 HIS F:94 F:94 196.0 1.0 S 41.8 27.4 196.0 1.0 0.0 HOH
 3.392
 N
 O
HIS S:94 f:94 134.0 0.687 -62.9 84.3 134.0 0.687 0.0 HOH
 4.434
 O
 O
5wau 6 P00428 85.71 5e-64 X-RAY
 2017-08-09 HIS F:94 F:94 141.0 0.723 S 69.7 -63.7 141.0 0.723 0.0 HOH
 4.683
 N
 O
HIS S:94 f:94 146.0 0.749 T -74.2 71.0 146.0 0.749 0.0 HOH
 2.639
 O
 O
5x19 6 P00428 85.71 5e-64 X-RAY
 2017-08-09 HIS F:94 F:94 102.0 0.523 15.7 -120.5 102.0 0.523 0.0 HOH
 3.840
 O
 O
HIS S:94 S:94 73.0 0.374 -42.5 -64.0 NA NA NA
5x1b 6 P00428 85.71 5e-64 X-RAY
 2017-08-09 HIS F:94 F:94 80.0 0.41 29.1 -124.5 80.0 0.41 0.0 HOH
 2.668
 O
 O
HIS S:94 S:94 85.0 0.436 18.5 -104.4 NA NA NA
5x1f 6 P00428 85.71 5e-64 X-RAY
 2017-08-09 HIS F:94 F:94 124.0 0.636 B 93.3 -150.1 124.0 0.636 0.0 HOH
 3.219
 CE1
 O
HIS S:94 S:94 51.0 0.262 -110.4 -136.7 NA NA NA
5xth 50 P00428 85.71 5e-64 EM
 2017-09-13 HIS YA:94 2:94 39.0 0.2 -81.7 114.5 25.0 0.128 0.072 TA:P00396:0.036
VA:P00415:0.056
5xti 50 P00428 85.71 5e-64 EM
 2017-09-13 HIS YA:94 2:94 39.0 0.2 -81.6 114.5 24.0 0.123 0.077 TA:P00396:0.036
VA:P00415:0.056
HIS AE:94 B2:94 38.0 0.195 -81.7 114.5 24.0 0.123 0.072 VD:P00396:0.036
XD:P00415:0.056
5z84 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 50.0 0.256 -147.5 -170.6 50.0 0.256 0.0 HOH
 2.309
 CD2
 O
HIS S:94 S:94 113.0 0.579 131.6 -135.4 NA NA NA
5z85 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 93.0 0.477 131.3 164.5 93.0 0.477 0.0 HOH
 2.804
 NE2
 O
HIS S:94 S:94 83.0 0.426 152.5 -136.0 NA NA NA
5z86 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 102.0 0.523 119.0 117.3 102.0 0.523 0.0 HOH
 3.128
 CE1
 O
HIS S:94 S:94 108.0 0.554 98.2 140.8 NA NA NA
5zco 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 91.0 0.467 139.8 154.2 91.0 0.467 0.0 EDO
HOH
 6.567
2.333
 O
O
 C1
O
HIS S:94 S:94 112.0 0.574 116.6 140.0 NA NA NA
5zcp 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 100.0 0.513 140.4 151.5 100.0 0.513 0.0 EDO
HOH
 6.499
2.482
 O
NE2
 C1
O
HIS S:94 S:94 108.0 0.554 111.3 144.9 NA NA NA
5zcq 6 P00428 85.71 5e-64 X-RAY
 2018-08-15 HIS F:94 F:94 107.0 0.549 128.8 143.9 107.0 0.549 0.0 EDO
EDO
HOH
 6.531
6.209
3.848
 O
O
O
 O1
O1
O
HIS S:94 S:94 93.0 0.477 43.1 -160.3 NA NA NA
6j8m 6 P00428 85.71 5e-64 X-RAY
 2019-06-26 HIS F:94 F:94 95.0 0.487 119.7 152.8 95.0 0.487 0.0 HOH
 2.578
 NE2
 O
HIS S:94 S:94 92.0 0.472 -73.4 -178.6 NA NA NA
6juw 6 P00428 85.71 5e-64 X-RAY
 2020-03-25 HIS F:94 F:94 42.0 0.215 -157.6 -179.9 42.0 0.215 0.0 EDO
EDO
HOH
 9.957
2.621
3.735
 CE1
NE2
ND1
 O2
O2
O
HIS S:94 S:94 81.0 0.415 -169.6 139.9 81.0 0.415 0.0 EDO
HOH
 5.709
2.852
 O
CB
 C2
O
6jy3 6 P00428 85.71 5e-64 X-RAY
 2019-09-18 HIS F:94 NA:NA DO NA DO DO DO NA NA NA
6jy4 6 P00428 85.71 5e-64 X-RAY
 2019-09-18 HIS F:94 NA:NA DO NA DO DO DO NA NA NA
6nkn 6 P00428 85.71 5e-64 X-RAY
 2019-03-20 HIS F:94 F:94 65.0 0.333 52.6 -169.8 65.0 0.333 0.0 HOH
 2.548
 O
 O
HIS S:94 S:94 130.0 0.667 109.5 -141.9 130.0 0.667 0.0 HOH
 3.021
 NE2
 O
6nmf 6 P00428 85.71 5e-64 X-RAY
 2019-03-13 HIS F:94 F:94 81.0 0.415 135.2 175.1 81.0 0.415 0.0 HOH
 6.899
 CB
 O
HIS S:94 S:94 123.0 0.631 -64.9 -71.7 123.0 0.631 0.0 HOH
 2.260
 O
 O
6nmp 6 P00428 85.71 5e-64 X-RAY
 2019-03-13 HIS F:94 F:94 110.0 0.564 122.8 161.1 110.0 0.564 0.0 HOH
 2.561
 N
 O
HIS S:94 S:94 129.0 0.662 72.7 -176.3 129.0 0.662 0.0 HOH
 2.244
 O
 O
7coh 6 P00428 85.71 5e-64 X-RAY
 2021-04-07 HIS F:94 NA:NA DO NA DO DO DO NA NA NA
HIS S:94 NA:NA DO NA DO DO DO NA NA NA
7ev7 6 P00428 85.71 5e-64 X-RAY
 2021-07-14 HIS F:94 F:94 187.0 0.959 41.4 360.0 187.0 0.959 0.0 HOH
 2.249
 O
 O
HIS S:94 S:94 172.0 0.882 37.0 360.0 NA NA NA
5xdq 6 P00428 85.11 9e-61 X-RAY
 2017-07-12 HIS F:94 F:94 210.0 NA 54.1 360.0 210.0 NA NA HOH
 2.764
 ND1
 O
HIS S:94 S:94 189.0 NA 52.4 360.0 NA NA NA
5xdx 6 P00428 85.11 9e-61 X-RAY
 2018-02-07 HIS F:94 F:94 194.0 NA 72.4 360.0 194.0 NA NA EDO
HOH
 4.972
6.309
 OXT
NE2
 C1
O
HIS S:94 S:94 217.0 NA 23.9 360.0 NA NA NA
7cp5 6 P00428 85.11 9e-61 X-RAY
 2021-07-21 HIS F:94 F:94 172.0 NA -156.7 360.0 172.0 NA NA EDO
HOH
 3.403
2.525
 CE1
ND1
 C1
O
HIS S:94 S:94 197.0 NA -7.7 360.0 197.0 NA NA EDO
HOH
 5.621
2.472
 NE2
ND1
 O2
O
7d5w 6 P00428 85.11 9e-61 X-RAY
 2021-07-21 HIS F:94 F:94 173.0 NA -158.8 360.0 172.0 NA NA A:P00396:NA
 EDO
HOH
 3.417
2.416
 CE1
ND1
 C1
O
HIS S:94 S:94 206.0 NA 169.2 360.0 206.0 NA NA EDO
HOH
 4.565
2.399
 O
OXT
 O2
O
7d5x 6 P00428 85.11 9e-61 X-RAY
 2021-07-21 HIS F:94 F:94 177.0 NA 116.3 360.0 177.0 NA NA EDO
HOH
 6.573
2.592
 O
O
 C1
O
HIS S:94 S:94 187.0 NA 73.0 360.0 187.0 NA NA EDO
HOH
 6.526
2.647
 CA
NE2
 C1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p10606-f1 1 P10606 100.0 8e-94 GLN A:125 A:125 47.0 0.261 -118.3 129.5